Modulation of Natural Killer Cell Cytotoxicity in Human Cytomegalovirus Infection: The Role of Endogenous Class I Major Histocompatibility Complex and a Viral Class I Homolog

HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C

1998 • 2,114 citations

Selective rejection of H–2-deficient lymphoma variants suggests alternative immune defence strategy

1986 • 2,102 citations

Severe Herpesvirus Infections in an Adolescent without Natural Killer Cells

1989 • 1,251 citations

Restoration of Viral Immunity in Immunodeficient Humans by the Adoptive Transfer of T Cell Clones

1992 • 1,227 citations

A Common Inhibitory Receptor for Major Histocompatibility Complex Class I Molecules on Human Lymphoid and Myelomonocytic Cells

1997 • 933 citations

Reactivation of Latent Human Cytomegalovirus by Allogeneic Stimulation of Blood Cells from Healthy Donors

1997 • 690 citations

A Novel Immunoglobulin Superfamily Receptor for Cellular and Viral MHC Class I Molecules

1997 • 681 citations

Cytotoxic T Cells in Cytomegalovirus Infection

1982 • 610 citations

The human major histocompatibility complex class Ib molecule HLA‐E binds signal sequence‐derived peptides with primary anchor residues at positions 2 and 9

1997 • 489 citations

Human cytomegalovirus encodes a glycoprotein homologous to MHC class-I antigens

1988 • 470 citations

Serum-free medium for generation and propagation of functional human cytotoxic and helper T cell clones

1984 • 392 citations

A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules.

1997 • 327 citations

The class I MHC homologue of human cytomegalovirus inhibits attack by natural killer cells

1997 • 327 citations

Adoptive transfer studies demonstrating the antiviral effect of natural killer cells in vivo.

1985 • 327 citations

Superantigen-Dependent, Cell-Mediated Cytotoxicity Inhibited by MHC Class I Receptors on T Lymphocytes

1995 • 316 citations

Peptide Specificity in the Recognition of MHC Class I by Natural Killer Cell Clones

1995 • 308 citations

Inhibition of natural killer cells by a cytomegalovirus MHC class I homologue in vivo

1997 • 305 citations

Cloning of novel immunoglobulin superfamily receptors expressed on human myeloid and lymphoid cells: Structural evidence for new stimulatory and inhibitory pathways

1997 • 298 citations

A complex between the MHC class I homologue encoded by human cytomegalovirus and β2 microglobulin

1990 • 246 citations

The effect of the Cmv-1 resistance gene, which is linked to the natural killer cell gene complex, is mediated by natural killer cells.

1992 • 242 citations

Human cytomegalovirus down-regulates HLA class I expression by reducing the stability of class I H chains.

1993 • 215 citations

CD94 and a Novel Associated Protein (94AP) Form a NK Cell Receptor Involved in the Recognition of HLA-A, HLA-B, and HLA-C Allotypes

1996 • 187 citations

Specificity of HLA class I antigen recognition by human NK clones: evidence for clonal heterogeneity, protection by self and non-self alleles, and influence of the target cell type.

1993 • 178 citations

The natural killer gene complex: a genetic basis for understanding natural killer cell function and innate immunity

1997 • 154 citations

The MHC class I homolog encoded by human cytomegalovirus binds endogenous peptides

1995 • 144 citations

Human cytomegalovirus in a SCID-hu mouse: thymic epithelial cells are prominent targets of viral replication.

1993 • 130 citations

Multicolor immunofluorescence and flow cytometry

1991 • 87 citations

Construction and characterization of a human cytomegalovirus mutant with the UL18 (class I homolog) gene deleted

1992 • 81 citations

NK cell recognition of major histocompatibility complex class I molecules

1995 • 40 citations

General role of HLA class I molecules in the protection of target cells from lysis by natural killer cells: evidence that the free heavy chains of class I molecules are not sufficient to mediate the protective effect

1995 • 36 citations

Peptides bound endogenously by HLA‐Cw*0304 expressed in LCL 721. 221 cells include a peptide derived from HLA‐E

1996 • 13 citations