Identification of phosphorylated 422(aP2) protein as pp15, the 15-kilodalton target of the insulin receptor tyrosine kinase in 3T3-L1 adipocytes.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

The Reliability of Molecular Weight Determinations by Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis

1969 • 20,498 citations

A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids

1984 • 3,959 citations

PROTEIN-TYROSINE KINASES

1985 • 2,198 citations

After Insulin Binds

1987 • 687 citations

Insulin stimulates tyrosine phosphorylation of the insulin receptor in a cell-free system

1982 • 680 citations

Insulin rapidly stimulates tyrosine phosphorylation of a Mr-185,000 protein in intact cells

1985 • 665 citations

Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin.

1987 • 648 citations

Evidence for the involvement of vicinal sulfhydryl groups in insulin-activated hexose transport by 3T3-L1 adipocytes.

1985 • 512 citations

A cascade of tyrosine autophosphorylation in the beta-subunit activates the phosphotransferase of the insulin receptor.

1988 • 467 citations

The insulin-mimetic effects of vanadate in isolated rat adipocytes. Dissociation from effects of vanadate as a (Na+-K+)ATPase inhibitor.

1980 • 392 citations

A novel mechanism for the insulin-like effect of vanadate on glycogen synthase in rat adipocytes.

1984 • 351 citations

Expression of specific mRNAs during adipose differentiation: identification of an mRNA encoding a homologue of myelin P2 protein.

1984 • 329 citations

Evidence for an increase in transcription of specific mRNAs during differentiation of 3T3-L1 preadipocytes.

1985 • 292 citations

Insulin activates a tyrosine-specific protein kinase in extracts of 3T3-L1 adipocytes and human placenta.

1982 • 287 citations

Insulin-stimulated tyrosine phosphorylation of the insulin receptor in detergent extracts of human placental membranes. Comparison to epidermal growth factor-stimulated phosphorylation.

1982 • 254 citations

The three-dimensional structure of P2 myelin protein.

1988 • 221 citations

Identification of a polypeptide growth inhibitor from bovine mammary gland. Sequence homology to fatty acid- and retinoid-binding proteins.

1987 • 201 citations

Insulin receptor is an insulin-dependent tyrosine protein kinase: copurification of insulin-binding activity and protein kinase activity to homogeneity from human placenta.

1984 • 201 citations

Cloning of a cDNA encoding rat intestinal fatty acid binding protein.

1984 • 198 citations

Characterization of the insulin receptor kinase purified from human placental membranes.

1983 • 196 citations

Tyrosine phosphorylation of common and specific sets of cellular proteins rapidly induced by insulin, insulin-like growth factor I, and epidermal growth factor in an intact cell.

1987 • 195 citations

Identification of insulin receptor tyrosine residues autophosphorylated in vitro.

1987 • 182 citations

Insulin-activated tyrosine phosphorylation of a 15-kilodalton protein in intact 3T3-L1 adipocytes.

1987 • 181 citations

Developmentally regulated mRNAs in 3T3-adipocytes: analysis of transcriptional control.

1985 • 170 citations

A mild procedure for the rapid release of cytoplasmic enzymes from cultured animal cells

1979 • 144 citations

The primary structure of bovine cellular retinoic acid-binding protein.

1985 • 124 citations

The complete amino acid sequence of the P2 protein in bovine peripheral nerve myelin

1980 • 122 citations

Rat heart fatty acid-binding protein is highly homologous to the murine adipocyte 422 protein and the P2 protein of peripheral nerve myelin.

1986 • 111 citations

Effect of vanadate on the cellular accumulation of pp15, an apparent product of insulin receptor tyrosine kinase action.

1988 • 103 citations

Tissue specific expression of p422 protein, a putative lipid carrier, in mouse adipocytes

1985 • 98 citations

Insulin rapidly stimulates phosphorylation of a 46-kDa membrane protein on tyrosine residues as well as phosphorylation of several soluble proteins in intact fat cells.

1987 • 97 citations

Effect of phenylarsine oxide on insulin-dependent protein phosphorylation and glucose transport in 3T3-L1 adipocytes.

1987 • 79 citations

A close structural relationship of rat liver Z-protein to cellular retinoid binding proteins and peripheral nerve myellin P2 protein

1982 • 77 citations

Regulation of insulin receptor metabolism. Differentiation-induced alteration of receptor synthesis and degradation.

1981 • 76 citations

Insulin-dependent phosphorylation of the insulin receptor-protein kinase and activation of glucose transport in 3T3-L1 adipocytes.

1986 • 76 citations

Homogeneous functional insulin receptor from 3T3-L1 adipocytes. Purification using N alpha B1-(biotinyl-epsilon-aminocaproyl)insulin and avidin-sepharose.

1985 • 69 citations

Kinetic evidence for activating and non-activating components of autophosphorylation of the insulin receptor protein kinase

1986 • 65 citations

Cloning and sequencing of a full length cDNA corresponding to human cellular retinol-binding protein

1985 • 48 citations

Insulin and insulin-like growth factor 1 stimulate the phosphorylation on tyrosine of a 160 kDa cytosolic protein in 3T3-L1 adipocytes

1988 • 48 citations