Differential proteolytic activation of factor VIII-von Willebrand factor complex by thrombin.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes.

1987 • 5,066 citations

Silver stain for proteins in polyacrylamide gels: A modified procedure with enhanced uniform sensitivity

1981 • 4,191 citations

Molecular cloning of a cDNA encoding human antihaemophilic factor

1984 • 937 citations

Structure of human factor VIII

1984 • 898 citations

COFACTOR PROTEINS IN THE ASSEMBLY AND EXPRESSION OF BLOOD CLOTTING ENZYME COMPLEXES

1988 • 535 citations

[Changes under the influence of high pressure of certain properties of myosin, actomyosin and actin].

1960 • 499 citations

Complete cDNA and derived amino acid sequence of human factor V.

1987 • 416 citations

Blood coagulation factors V and VIII: structural and functional similarities and their relationship to hemorrhagic and thrombotic disorders

1988 • 405 citations

Synthesis, processing, and secretion of recombinant human factor VIII expressed in mammalian cells.

1988 • 385 citations

The subunit structure of thrombin-activated factor V. Isolation of activated factor V, separation of subunits, and reconstitution of biological activity.

1979 • 356 citations

Association of the factor VIII light chain with von Willebrand factor.

1988 • 223 citations

[18] The coagulant enzyme from Bothrops atrox venom (batroxobin)

1976 • 209 citations

Monoclonal antibodies to porcine factor VIII coagulant and their use in the isolation of active coagulant protein

1982 • 178 citations

Purified human factor VIII procoagulant protein: comparative hemostatic response after infusions into hemophilic and von Willebrand disease dogs.

1985 • 175 citations

Proteolytic requirements for thrombin activation of anti-hemophilic factor (factor VIII).

1988 • 170 citations

The size of human factor VIII heterodimers and the effects produced by thrombin

1986 • 161 citations

Subunit structure of thrombin-activated porcine factor VIII

1989 • 147 citations

An immunogenic region within residues Val1670-Glu1684 of the factor VIII light chain induces antibodies which inhibit binding of factor VIII to von Willebrand factor.

1988 • 136 citations

Thrombocytin, a serine protease from Bothrops atrox venom. 2. Interaction with platelets and plasma-clotting factors

1979 • 122 citations

Human von Willebrand factor: a multivalent protein composed of identical subunits

1986 • 120 citations

Stabilization of thrombin-activated porcine factor VIII:C by factor IXa phospholipid

1984 • 117 citations

Activation of porcine factor VIII:C by thrombin and factor Xa

1985 • 114 citations

Interaction of factor VIII-von Willebrand Factor with phospholipid vesicles

1981 • 104 citations

Thrombocytin, a serine protease from Bothrops atrox venom. 1. Purification and characterization of the enzyme

1979 • 98 citations

Determination of absorption coefficients of purified proteins by conventional ultraviolet spectrophotometry and chromatography combined with multiwavelength detection

1985 • 84 citations

A Simple Method for Preparing Fibrinogen

1966 • 82 citations

Stoichiometry of the porcine factor VIII-von Willebrand factor association.

1987 • 59 citations

Platelets and von Willebrand disease.

1985 • 51 citations

Molecular characterization of commercial porcine factor VIII concentrate

1988 • 45 citations

Degradation of coagulation proteins by an enzyme from Malayan pit viper (Akistrodon rhodostoma) venom

1987 • 27 citations