Molecular Dynamics Simulations of Gly-12→Val Mutant of p21 : Dynamic Inhibition Mechanism

A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules

1995 • 12,826 citations

ras GENES

1987 • 3,818 citations

Proteins regulating Ras and its relatives

1993 • 1,930 citations

The Ras-RasGAP Complex: Structural Basis for GTPase Activation and Its Loss in Oncogenic Ras Mutants

1997 • 1,482 citations

Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis.

1990 • 1,077 citations

Molecular Switch for Signal Transduction: Structural Differences Between Active and Inactive Forms of Protooncogenic ras Proteins

1990 • 1,037 citations

Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation

1989 • 881 citations

Protein Data Bank

1984 • 731 citations

Passage of phenotypes of chemically transformed cells via transfection of DNA and chromatin.

1979 • 491 citations

Three-dimensional structures of H-ras p21 mutants: Molecular basis for their inability to function as signal switch molecules

1990 • 395 citations

Gaussian 94 user's reference

1996 • 354 citations

Regulation of Phosphorylation Pathways by p21 GTPases

1996 • 300 citations

Mutational and kinetic analyses of the GTPase-activating protein (GAP)-p21 interaction: the C-terminal domain of GAP is not sufficient for full activity.

1992 • 268 citations

Ras-catalyzed hydrolysis of GTP: a new perspective from model studies.

1996 • 205 citations

Probing the Structure and Mechanism of Ras Protein with an Expanded Genetic Code

1993 • 130 citations

Aluminium fluoride associates with the small guanine nucleotide binding proteins

1997 • 72 citations

Development of MD Engine: High-speed accelerator with parallel processor design for molecular dynamics simulations

1999 • 70 citations

Gaussian 98 Programmer's reference

1998 • 52 citations

Ab Initio Study of the Role of Lysine 16 for the Molecular Switching Mechanism of Ras Protein p21

1999 • 37 citations

A New Function of p120-GTPase-activating Protein

1997 • 15 citations

Time-resolved crystallography on H-ras p21

1992 • 13 citations

The Importance of the Role of Lysine 16 and GAP on the Molecular Switching Mechanism of Ras Protein p21.

1997 • 2 citations