Metal-responsive transcription factor-1 (MTF-1) selects different types of metal response elements at low vs. high zinc concentration

Mapping of RNA by a modification of the Berk-Sharp procedure: the 5′ termini of 15 S β-globin mRNA precursor and mature 10 S β-globin mRNA have identical map coordinates

1979 • 1,286 citations

Characterization of DNA sequences through which cadmium and glucocorticoid hormones induce human metallothionein-IIA gene

1984 • 955 citations

The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain

1989 • 781 citations

A family of human CCAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple cDNAs

1988 • 747 citations

Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes

1992 • 577 citations

The transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expression.

1994 • 489 citations

A 12-base-pair DNA motif that is repeated several times in metallothionein gene promoters confers metal regulation to a heterologous gene.

1984 • 424 citations

Cloned transcription factor MTF-1 activates the mouse metallothionein I promoter.

1993 • 382 citations

Different activation domains stimulate transcription from remote (‘enhancer’) and proximal (‘promoter’) positions.

1992 • 359 citations

Identification of multiple metal regulatory elements in mouse metallothionein-I promoter by assaying synthetic sequences

1985 • 353 citations

Cellular zinc sensors: MTF-1 regulation of gene expression.

2001 • 323 citations

Cloning and characterization of mCtBP2, a co-repressor that associates with basic Kruppel-like factor and other mammalian transcriptional regulators

1998 • 320 citations

A zinc-responsive factor interacts with a metal-regulated enhancer element (MRE) of the mouse metallothionein-I gene.

1988 • 297 citations

Genome-wide characterization of the Zap1p zinc-responsive regulon in yeast

2000 • 293 citations

Transcription factor Sp3 is silenced through SUMO modification by PIAS1

2002 • 261 citations

Embryonic lethality and liver degeneration in mice lacking the metal-responsive transcriptional activator MTF-1

1998 • 257 citations

OVEC, a versatile system to study transcription in mammalian cells and cell-free extracts

1987 • 255 citations

Toxicological aspects of metallothionein.

2000 • 242 citations

Oxidative Stress Activates Metal-responsive Transcription Factor-1 Binding Activity

1996 • 237 citations

Activity of Metal-Responsive Transcription Factor 1 by Toxic Heavy Metals and H₂O₂ In Vitro Is Modulated by Metallothionein

2003 • 235 citations

Building a metal-responsive promoter with synthetic regulatory elements.

1985 • 199 citations

The DNA Binding Activity of Metal Response Element-binding Transcription Factor-1 Is Activated in vivo and in Vitro by Zinc, but Not by Other Transition Metals

1998 • 186 citations

Duplicated heavy metal control sequences of the mouse metallothionein-I gene.

1984 • 167 citations

Metal Response Element (MRE)-Binding Transcription Factor-1 (MTF-1): Structure, Function, and Regulation

2001 • 166 citations

Concentration-dependent transcriptional activation or repression by Krüppel from a single binding site

1991 • 166 citations

Activation of metallothionein gene expression by hypoxia involves metal response elements and metal transcription factor-1.

1999 • 162 citations

Functional domains of the heavy metal-responsive transcription regulator MTF-1

1995 • 155 citations

Amino-terminal domain of NF1 binds to DNA as a dimer and activates adenovirus DNA replication.

1990 • 146 citations

Knockout of 'metal-responsive transcription factor' MTF-1 in Drosophila by homologous recombination reveals its central role in heavy metal homeostasis

2002 • 136 citations

Transcription factor nuclear factor I proteins form stable homo‐ and heterodimers

1994 • 135 citations

Target gene search for the metal-responsive transcription factor MTF-1

2001 • 135 citations

Reversible Activation of Mouse Metal Response Element-Binding Transcription Factor 1 DNA Binding Involves Zinc Interaction with the Zinc Finger Domain

1997 • 127 citations

Transcriptional activity and regulatory protein binding of metal‐responsive elements of the human metallothionein‐IIA gene

1999 • 118 citations

The Activation of the Rat Copper/Zinc Superoxide Dismutase Gene by Hydrogen Peroxide through the Hydrogen Peroxide-responsive Element and by Paraquat and Heat Shock through the Same Heat Shock Element

1999 • 109 citations

Metal-dependent binding of a factor in vivo to the metal-responsive elements of the metallothionein 1 gene promoter.

1987 • 87 citations

Metal-dependent SV40 viruses containing inducible enhancers from the upstream region of metallothionein genes.

1985 • 84 citations

Analysis of multiple forms of nuclear factor I in human and murine cell lines.

1990 • 80 citations

Transition metals modulate DNA-protein interactions of SP1 zinc finger domains with its cognate target site

1991 • 78 citations

Intracompartmental sorting of essential myosin light chains: Molecular dissection and in vivo monitoring by epitope tagging

1991 • 71 citations

Nuclear Factor I (NFI) Isoforms Differentially Activate Simple versus Complex NFI-responsive Promoters

1998 • 64 citations

Structural and functional analyses of DNA bending induced by Sp1 family transcription factors 1 1Edited by T. Richmond

1997 • 55 citations

A Novel Cysteine Cluster in Human Metal-responsive Transcription Factor 1 Is Required for Heavy Metal-induced Transcriptional Activation in Vivo

2004 • 55 citations

Arsenite-inducible RNA-associated protein (AIRAP) protects cells from arsenite toxicity

2001 • 52 citations

CASTing for multicomponent DNA-binding complexes

1993 • 52 citations

Ribosomal Protein S25 mRNA Partners with MTF-1 and La to Provide a p53-mediated Mechanism for Survival or Death

2002 • 49 citations

Cadmium and lead interactions with transcription factor IIIA from Xenopus laevis: a model for zinc finger protein reactions with toxic metal ions and metallothionein

2000 • 42 citations

Testis-Specific and Ubiquitous Proteins Bind to Functionally Important Regions of the Mouse Protamine-1 Promoter1

1994 • 41 citations

Conformational Heterogeneity in the C-terminal Zinc Fingers of Human MTF-1

2001 • 33 citations

Downregulation of Constitutive and Heavy Metal-Induced Metallothionein-I Expression by Nuclear Factor I

2001 • 31 citations

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