Soluble and insoluble fiber influences on cancer development

Short chain fatty acids in human large intestine, portal, hepatic and venous blood.

1987 • 2,744 citations

Vegetables, Fruit, and Cancer Prevention

1996 • 2,157 citations

Dietary Fiber, Glycemic Load, and Risk of Non—insulin-dependent Diabetes Mellitus in Women

1997 • 1,713 citations

Dietary fibres, fibre analogues, and glucose tolerance: importance of viscosity.

1978 • 1,165 citations

Insulin and colon cancer

1995 • 815 citations

Dietary Factors and Risk of Breast Cancer: Combined Analysis of 12 Case--Control Studies

1990 • 763 citations

Selected Indigestible Oligosaccharides Affect Large Bowel Mass, Cecal and Fecal Short-Chain Fatty Acids, pH and Microflora in Rats ,

1997 • 722 citations

Western diet and Western diseases: Some hormonal and biochemical mechanisms and associations

1990 • 691 citations

Urinary excretion of lignans and isoflavonoid phytoestrogens in Japanese men and women consuming a traditional Japanese diet

1991 • 665 citations

Stimulatory effect of short-chain fatty acids on epithelial cell proliferation in the rat intestine: a possible explanation for trophic effects of fermentable fibre, gut microbes and luminal trophic factors

1987 • 656 citations

Phytoestrogens: epidemiology and a possible role in cancer protection.

1995 • 558 citations

Butyrate production from dietary fibre and protection against large bowel cancer in a rat model.

1993 • 555 citations

Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53‐independent pathway: Implications for the possible role of dietary fibre in the prevention of large‐bowel cancer

1993 • 539 citations

Dietary Intake of Fiber and Decreased Risk of Cancers of the Colon and Rectum: Evidence From the Combined Analysis of 13 Case-Control Studies

1992 • 510 citations

Short-Chain Fatty Acids in the Human Colon: Relation to Gastrointestinal Health and Disease

1996 • 487 citations

Estrogen Excretion Patterns and Plasma Levels in Vegetarian and Omnivorous Women

1982 • 477 citations

Fecal weight, colon cancer risk, and dietary intake of nonstarch polysaccharides (dietary fiber)

1992 • 464 citations

Promoting effect of bile acids in colon carcinogenesis in germ-free and conventional F344 rats.

1977 • 436 citations

Dietary phytoestrogens and cancer: in vitro and in vivo studies

1992 • 435 citations

Digestion and physiological properties of resistant starch in the human large bowel

1996 • 410 citations

COLONIC RESPONSE TO DIETARY FIBRE FROM CARROT, CABBAGE, APPLE, BRAN, AND GUAR GUM

1978 • 404 citations

Metabolic epidemiology of colon cancer:Fecal bile acids and neutral sterols in colon cancer patients and patients with adenomatous polyps

1977 • 404 citations

Role of bile acids in colorectal carcinogenesis

1995 • 351 citations

Role of short-chain fatty acids in the prevention of colorectal cancer

1995 • 349 citations

Dietary fiber, glycemic load, and risk of non-insulin-dependent diabetes mellitus in women

1997 • 344 citations

High-carbohydrate, high-fiber diets increase peripheral insulin sensitivity in healthy young and old adults

1990 • 342 citations

Association of Soy and Fiber Consumption with the Risk of Endometrial Cancer

1997 • 340 citations

The risk of cancer and dysplasia among ulcerative colitis patients with primary sclerosing cholangitis.

1997 • 320 citations

Starch intake and colorectal cancer risk: an international comparison

1994 • 316 citations

Western diet and Western diseases: Some hormonal and biochemical mechanisms and associations

1990 • 301 citations

Health benefits and practical aspects of high-fiber diets

1994 • 278 citations

The relationship between estrogen levels and diets of Caucasian American and Oriental immigrant women

1986 • 262 citations

Calcium ameliorates the toxic effect of deoxycholic acid on colonic epithelium

1983 • 253 citations

Breast Cancer

1992 • 249 citations

Whole‐grain consumption and chronic disease: Protective mechanisms

1997 • 244 citations

Dietary fiber, vitamins A, C, and E, and risk of breast cancer: a cohort study

1993 • 224 citations

High-fiber diet reduces serum estrogen concentrations in premenopausal women

1991 • 220 citations

Ten Different Dietary Fibers Have Significantly Different Effects on Serum and Liver Lipids of Cholesterol-Fed Rats

1994 • 214 citations

Vitamins C and E, retinol, beta-carotene and dietary fibre in relation to breast cancer risk: a prospective cohort study

1997 • 197 citations

Effects of Dietary Fiber and Carbohydrate on Glucose and Lipoprotein Metabolism in Diabetic Patients

1991 • 186 citations

Dietary factors and the risk of endometrial cancer

1993 • 177 citations

Effect of fiber from fruits and vegetables on metabolic responses of human subjects II. Calcium, magnesium, iron, and silicon balances

1979 • 177 citations

Modulation of colonic epithelial cell proliferation, histone acetylation, and luminal short chain fatty acids by variation of dietary fiber (wheat bran) in rats.

1992 • 177 citations

Refined Carbohydrate Foods and Disease: Some Implications of Dietary Fibre

1976 • 173 citations

Relationship between colonic luminal pH, cell proliferation, and colon carcinogenesis in 1,2-dimethylhydrazine treated rats fed high fiber diets.

1986 • 172 citations

Butyrate and the colonocyte

1996 • 160 citations

Diet and Risk of Colorectal Adenomas: Macronutrients, Cholesterol, and Fiber

1993 • 157 citations

The effect of dietary fat and fiber on serum estrogen concentrations in premenopausal women under controlled dietary conditions

1994 • 153 citations

Diet and serum sex hormones in healthy men

1984 • 152 citations

Dietary fiber: hyperlipidemia, hypertension, and coronary heart disease.

1986 • 151 citations

Effect of short‐chain fatty acids on calcium absorption by the rat colon

1991 • 149 citations

Different fibers have different regional effects on luminal contents of rat colon

1991 • 144 citations

Nutrition and cancer: A summary of the evidence

1996 • 143 citations

Role of Fat, Animal Protein, and Dietary Fiber in Breast Cancer Etiology: A Case-Control Study2

1986 • 143 citations

Parenteral nutrition supplemented with short-chain fatty acids: effect on the small-bowel mucosa in normal rats

1990 • 138 citations

A Population-based Case-Control Study of Dietary Factors and Endometrial Cancer in Shanghai, People's Republic of China

1993 • 136 citations

Biochemical epidemiology of colon cancer: effect of types of dietary fiber on fecal mutagens, acid, and neutral sterols in healthy subjects.

1989 • 133 citations

Diet Composition Related to Body Fat in a Multivariate Study of 203 Men

1996 • 133 citations

Nutrition and diet in the etiology of endometrial cancer

1986 • 128 citations

Effect of wheat fiber on blood lipids, fecal steroid excretion and serum iron

1975 • 128 citations

Viscosity and fermentability as attributes of dietary fiber responsible for the hypocholesterolemic effect in hamsters.

1993 • 125 citations

Wheat bran suppresses potato starch--potentiated colorectal tumorigenesis at the aberrant crypt stage in a rat model

1996 • 123 citations

Effect of exercise and physical fitness on large intestinal function

1989 • 120 citations

A High Amylose (Amylomaize) Starch Raises Proximal Large Bowel Starch and Increases Colon Length in Pigs , ,

1997 • 119 citations

Effects of Cellulose Added to Diets of Low and High Fiber Content upon the Metabolism of Calcium, Magnesium, Zinc and Phosphorus by Man

1977 • 119 citations

Phytoestrogens: Epidemiology and a Possible Role in Cancer Protection

1995 • 116 citations

Relationships between Viscosity of Hydroxypropyl Methylcellulose and Plasma Cholesterol in Hamsters

1993 • 111 citations

Dietary fiber and distal colorectal adenoma in men.

1997 • 111 citations

Diet and Endometrial Cancer: A Case-Control Study

1993 • 109 citations

Effects of a very low fat, high fiber diet on serum hormones and menstrual function implications for breast cancer prevention

1995 • 102 citations

Medicine and the Law

1984 • 97 citations

Dietary fiber, phytoestrogens, and breast cancer.

1992 • 96 citations

Breast Cancer 4

1981 • 96 citations

Insulin resistance, insulin‐like growth factor I and breast cancer: A hypothesis

1995 • 95 citations

Effect of meat and resistant starch on fecal excretion of apparentN‐nitroso compounds and ammonia from the human large bowel

1997 • 94 citations

Binding of zinc and iron to wheat bread, wheat bran, and their components

1977 • 94 citations

Nutritional and lifestyle habits and water-fiber interaction in colorectal adenoma etiology.

1997 • 93 citations

Diet and the excretion and enterohepatic cycling of estrogens

1987 • 93 citations

Studies on the role of specific dietary fibres in protection against colorectal cancer

1996 • 88 citations

Increased Intestinal Contents Viscosity Reduces Cholesterol Absorption Efficiency in Hamsters Fed Hydroxypropyl Methylcellulose

1996 • 87 citations

High-fiber diets and reduced risk of breast cancer

1994 • 86 citations

Dietary fiber, beta‐carotene and breast cancer: Results from a case‐control study

1990 • 85 citations

Modulation of N-Nitrosomethylurea-Induced Mammary Tumor Promotion by Dietary Fiber and Fat

1991 • 83 citations

Insulin-Like Growth Factors, Insulin-Like Growth Factor Binding Proteins and Ovarian Androgen Production

1994 • 82 citations

Long-Term Effects of Fermentable Fibers on Rat Colonic pH and Epithelial Cell Cycle

1988 • 81 citations

Semipurified dietary fiber and small-bowel morphology in rats

1982 • 79 citations

Dietary fibers differ in their effects on large bowel epithelial proliferation and fecal fermentation-dependent events in rats.

1995 • 78 citations

Dietary fibre, complex carbohydrate and coronary artery disease.

1995 • 72 citations

Effect of fiber from fruits and vegetables on metabolic responses of human subjects III. Zinc, copper, and phosphorus balances

1979 • 72 citations

Comparison of resistant starch with cellulose diet on 1,2- dimethylhydrazine-induced colonic carcinogenesis in rats

1996 • 69 citations

Postprandial serum glucose, insulin, and lipoprotein responses to high- and low-fiber diets

1995 • 69 citations

Hypocholesterolemic Effects of Different Bulk-Forming Hydrophilic Fibers as Adjuncts to Dietary Therapy in Mild to Moderate Hypercholesterolemia

1991 • 68 citations

Regulation of human colonic cell line proliferation and phenotype by sodium butyrate

1996 • 66 citations

Stimulatory Effect of Short-Chain Fatty Acids on Epithelial Cell Proliferation of Isolated and Denervated Jejunal Segment of the Rat

1989 • 66 citations

Extracellular pH regulation in microdomains of colonic crypts: effects of short-chain fatty acids.

1995 • 65 citations

In Vivo Crypt Surface Hyperproliferation Is Decreased by Butyrate and Increased by Deoxycholate in Normal Rat Colon: Associated In Vivo Effects on c‐Fos and c‐Jun Expression

1996 • 64 citations

DIETARY FIBRE, DIABETES, AND HYPERLIPIDÆMIA

1979 • 63 citations

Soy and rye diets inhibit the development of Dunning R3327 prostatic adenocarcinoma in rats

1997 • 62 citations

Fat and fiber intakes in relation to serum estrogen concentration in premenopausal Japanese women

1997 • 61 citations

Dietary fiber and the chemopreventive modelation of colon carcinogenesis

1996 • 60 citations

Alcohol as a cause of cancer.

1995 • 59 citations

Dietary fat and fiber modulate colonic cell proliferation in an interactive site‐specific manner

1993 • 59 citations

Potential synergism between wheat bran and psyllium: enhanced inhibition of colon cancer

1993 • 58 citations

Wheat Bran and Psylium Diets: Effects on N-Methylnitrosourea-Induced Mammary Tumorigenesis in F344 Rats

1996 • 58 citations

In vitro production of short-chain fatty acids by bacterial fermentation of dietary fiber compared with effects of those fibers on hepatic sterol synthesis in rats.

1993 • 56 citations

Dietary Fat and Fiber Alter Rat Colonic Mucosal Lipid Mediators and Cell Proliferation

1993 • 54 citations

Dietary fibers stimulate colonic cell proliferation by different mechanisms at different sites

1994 • 54 citations

Dietary supplementation with pectin and guar gum on 1,2-dimethylhydrazine-induced colon carcinogenesis in rats

1992 • 53 citations

Dietary fiber and risk of breast cancer: A case‐control study in Uruguay

1997 • 52 citations

DIET AND HISTOLOGIC TYPES OF BENIGN BREAST DISEASE DEFINED BY SUBSEQUENT RISK OF BREAST CANCER

1990 • 49 citations

Analysis of bile acids in colon residual liquid or fecal material in patients with colorectal neoplasia and control subjects

1997 • 48 citations

Dietary Fiber in the Prevention of Cardiovascular Disease

1993 • 47 citations

Dietary fat, fiber, and carcinogen alter fecal diacylglycerol composition and mass.

1995 • 45 citations

Metabolic and Morphometric Changes in Small and Large Intestine in Rats Fed High-Fiber Diets

1996 • 42 citations

Glycemic and insulinemic responses after ingestion of ethnic foods by NIDDM and healthy subjects

1992 • 41 citations

Effect of dietary cellulose on cell proliferation and progression of 1,2-dimethylhydrazine-induced colon carcinogenesis in rats.

1989 • 40 citations

Effect of dietary fiber on colonic cell proliferation and its relationship to colon carcinogenesis

1987 • 40 citations

Biochemical epidemiology of colon cancer: Effect of types of dietary fiber on colonic diacylglycerols in women

1994 • 38 citations

Enrichment of an Israeli ethnic food with fibres and their effects on the glycaemic and insulinaemic responses in subjects with non-insulin-dependent diabetes mellitus

1995 • 37 citations

Comparison of the influence of dietary fibre sources with different proportions of soluble and insoluble fibre on Ca, Mg, Fe, Zn, Mn and Cu apparent absorption in rats

1996 • 37 citations

The Influence of Dietary Fiber on Proliferation of Intestinal Mucosal Cells in Miniature Swine May Not Be Mediated Primarily by Fermentation

1992 • 36 citations

Effects of resistant starch‐ and Vitamin a‐supplemented diets on the promotion of precursor lesions of colon cancer in rats

1997 • 35 citations

Growth hormone, insulin-like growth factor-I axis, and insulin secretion in hyperandrogenic adolescents

1995 • 34 citations

Effect of the dietary fibre content of lifelong diet on colonic cellular proliferation in the rat.

1992 • 32 citations

Effects of cereal and vegetable fiber feeding on potential risk factors for colon cancer.

1992 • 32 citations

Cancer risk: possible protective role of high carbohydrate high fiber diets.

1986 • 32 citations

Achieving dietary recommendations: Whole‐grain foods in the food guide pyramid

1994 • 32 citations

Dietary fiber and risk of benign proliferative epithelial disorders of the breast

1995 • 31 citations

The risk of cancer and dysplasia among ulcerative colitis patients with primary sclerosing cholangitis

1998 • 31 citations

Dietary fat and fiber alter rat colonic protein kinase C isozyme expression.

1995 • 28 citations

Effects of Deoxycholic Acid and Butyrate on Mucosal Prostaglandin E2 Release and Cell Proliferation in the Human Sigmoid Colon

1995 • 27 citations

Effect of a dietary fiber (beet fiber) on Dimethylhydrazine‐induced colon cancer in wistar rats

1992 • 25 citations

Dietary guar gum alters colonic microbial fermentation in azoxymethane-treated rats.

1996 • 25 citations

Dietary Fiber: Fact and Fiction

1996 • 25 citations

Tissue hypertrophy and epithelial proliferation rate in the gut of rats fed on bread and haricot beans (Phaseolus vulgaris)

1996 • 25 citations

Antagonistic effects of deoxycholic acid and butyrate on epithelial cell proliferation in the proximal and distal human colon.

1994 • 24 citations

Effect of reduced rate of carbohydrate absorption on carbohydrate and lipid metabolism.

1995 • 23 citations

Time-lag effect of dietary fiber and fat intake ratio on Japanese colon cancer mortality.

1996 • 23 citations

Evaluation in rats of the dose-response relationship among colonic mucosal growth, colonic fermentation, and dietary fiber

1996 • 22 citations

Intra-Caecal Short Chain Fatty Acids Are Altered by Dietary Pectin in the Rat

1984 • 22 citations

Biliary control of beta-glucuronidase activity in the luminal contents of the rat ileum, cecum, and rectum.

1982 • 21 citations

Cancer Prevention: The Roles of Diet and Chemoprevention

1997 • 21 citations

Is there a causal connection between bile acids and colorectal cancer?

1996 • 20 citations

Retention of Iron by Rat Intestine in Vivo as Affected by Dietary Fiber, Ascorbate and Citrate

1986 • 20 citations

Dissociation of colonic apical Na/H exchange activity from bulk cytoplasmic pH

1996 • 19 citations

The Cholesterol Controversy

1996 • 18 citations

Suppression of a a carcinogen (1,2-dimethylhydrazine dihydrochloride)-induced increase in mitotic activity in the colonic crypts of rats by addition of dietary cellulose.

1989 • 18 citations

Fiber supplementation results in expanded proliferative zones in rat gastric mucosa

1987 • 17 citations

Effects of wheat bran and energy restriction on onset of puberty, cell proliferation and development of mammary tissue in female rats

1992 • 17 citations

Cellulose and pectin alter intestinal β-glucuronidase (EC 3.2.1.31) in the rat

1985 • 15 citations

Effects of Cottonseed Dietary Fiber on Metabolic Parameters in Diabetic Rats and Non-Insulin-Dependent Diabetic Humans

1988 • 14 citations

Hypocholesterolemic effects of different bulk-forming hydrophilic fibers as adjuncts to dietary therapy in mild to moderate hypercholesterolemia

1991 • 14 citations

Effects of High‐fiber diets on pathological changes in DMH‐induced rat colon cancer

1993 • 14 citations

Effects of oat rye fractions on biliary and faecal bile acid profiles in Syrian golden hamsters (Mesocricetus auratus)

1993 • 13 citations

Transforming growth factor alpha distribution in rectal crypts as a biomarker of decreased colon cancer risk in patients consuming cellulose.

1997 • 12 citations

Alcohol as a Cause of Cancer

1995 • 11 citations

Quantitative contribution of factors regulating rat colonic crypt epithelium: role of parenteral and enteral feeding, caloric intake, dietary cellulose level and the colon carcinogen DMH

1990 • 11 citations

A community-based feasibility study using wheat bran fiber supplementation to lower colon cancer risk

1991 • 10 citations

The effects of dietary fiber from lagenaria scineraria (yugao-melon) on colonic carcinogenesis in mice

1995 • 9 citations

DECREASED ABSORPTION OF CALCIUM, MAGNESIUM, ZINC AND PHOSPHORUS BY HUMANS DUE TO INCREASED FIBER AND PHOSPHORUS CONSUMPTION AS WHEAT BREAD

2009 • 7 citations

Preparation of a dietary fiber mixture derived from different sources and its metabolic effects in rats.

1993 • 7 citations

Stool weight and faecal pH in two South African populations with a dissimilar colon cancer risk.

1994 • 6 citations

Optimal diet for reducing the risk of arteriosclerosis.

1995 • 6 citations

Type of dietary fiber, not fat, alters phospholipase D and ornithine decarboxylase activities in the rat large intestine

1997 • 3 citations

EFFECTS OF DIETARY FIBRE ON DIMETHYLHYDRAZINE‐INDUCED CHANGES IN PROSTANOID CONCENTRATIONS IN RAT COLONIC MUCOSA

1995 • 2 citations

The ion exchange properties of human post‐mortem caecal and colonic mucus: The effect of sodium butyrate

1992 • 2 citations