Clinical Pharmacokinetics of Mirtazapine

Mirtazapine: efficacy and tolerability in comparison with fluoxetine in patients with moderate to severe major depressive disorder. Mirtazapine-Fluoxetine Study Group.

1998 • 159 citations

Efficacy and tolerability of mirtazapine versus citalopram: a double-blind, randomized study in patients with major depressive disorder

1999 • 145 citations

Mirtazapine

1998 • 141 citations

The Selective α2-Adrenoceptor Antagonist Mirtazapine (Org 3770) Enhances Noradrenergic and 5-HT1A-Mediated Serotonergic Neurotransmission

1995 • 116 citations

The α2-adrenoceptor antagonist Org 3770 enhances serotonin transmission in vivo

1994 • 104 citations

A double‐blind multicentre comparison of mirtazapine and amitriptyline in elderly depressed patients

1996 • 98 citations

Org 3770 (mirtazapine) versus trazodone: A placebo controlled trial in depressed elderly patients

1995 • 95 citations

A double-blind comparison of Org 3770, amitriptyline, and placebo in major depression.

1995 • 92 citations

Pharmacokinetics and Biotransformation of Mirtazapine in Human Volunteers

1998 • 92 citations

Psychopharmakotherapie

1996 • 89 citations

The α2-selective adrenoceptor antagonist org 3770 (mirtazapine, Remeron®) enhances noradrenergic and serotonergic transmission

1995 • 83 citations

Mirtazapine is more effective than trazodone: a double-blind controlled study in hospitalized patients with major depression.

1995 • 77 citations

In Vitro and In Vivo Studies on the Disposition of Mirtazapine in Humans

1997 • 76 citations

A double-blind placebo-controlled study of Org 3770 in depressed outpatients

1995 • 73 citations

A multicentre, double‐blind, clomipramine‐controlled efficacy and safety study of org 3770

1995 • 68 citations

Thiothixene Pharmacokinetic Interactions

1991 • 65 citations

Clinically relevant effect sizes in depression

1994 • 65 citations

Mirtazapine is more effective than trazodone

1995 • 64 citations

Org 3770 versus amitriptyline: A 6‐week randomized double‐blind multicentre trial in hospitalized depressed patients

1995 • 59 citations

A double-blind study comparing the efficacy and tolerability of mirtazapine and doxepin in patients with major depression

1995 • 56 citations

Concomitant use of mirtazapine and phenytoin: a drug-drug interaction study in healthy male subjects

2002 • 53 citations

Bioavailability of mirtazapine from Remeron® tablets after single and multiple oral dosing

1995 • 51 citations

Pharmacokinetic dose-proportionality study at steady state of mirtazapine from Remeron® tablets

1995 • 49 citations

Pharmacokinetics of Mirtazapine from Orally Administered Tablets: Influence of Gender, Age and Treatment Regimen

1996 • 47 citations

Actions and Interactions of Psychotropic Drugs on Human Performance and Mood: Single Doses of ORG 3770, Amitriptyline, and Diazepam

1989 • 42 citations

New developments in the treatment of depression.

1999 • 42 citations

Mirtazapine versus selective serotonin reuptake inhibitors.

1999 • 38 citations

A multicentre, double-blind, amitriptyline-controlled study of mirtazapine in patients with major depression

1996 • 36 citations

Mirtazapine pharmacokinetics with two dosage regimens and two pharmaceutical formulations.

1997 • 35 citations

Lack of drug interactions between mirtazapine and risperidone in psychiatric patients: a pilot study

1999 • 35 citations

Single-Dose Pharmacokinetics of Fluphenazine after Fluphenazine Decanoate Administration

1990 • 28 citations

Selection of an antidepressant: mirtazapine.

1997 • 28 citations

The Effects of Mirtazapine on the Interactions between Central Noradrenergic and Serotonergic Systems

1995 • 28 citations

Pharmacokinetics of mirtazapine and lithium in healthy male subjects

2000 • 23 citations

Concomitant use of mirtazapine and cimetidine: a drug-drug interaction study in healthy male subjects

2000 • 22 citations

Pharmacokinetics of mirtazapine from orally administered tablets: influence of a high-fat meal

1997 • 21 citations

Mirtazapine oral single dose kinetics in patients with different degrees of renal failure

1998 • 21 citations

A double-blind study comparing the efficacy and tolerability of mirtazapine and doxepin in patients with major depression

1995 • 21 citations

Influence of hepatic impairment on the pharmacokinetics of single doses of mirtazapine in elderly subjects

1993 • 6 citations

Contributions of the enantiomers of mirtazapine (Org 3770) and of its demethyl metabolite to its neurophamacological profile in rats

1990 • 5 citations

(+)-Mirtazapine and (+)-desmethylmirtazapine levels in rat brain in relation to in vivo blockade of α2 receptors

1996 • 3 citations

Pharmacokinetics of mirtazapine in combination with amitriptyline

1998 • 3 citations

P.1.034 In vivo study in humans on disposition of the enantiomers and metabolites of mirtazapine

1997 • 2 citations

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