Identification of Multiple Transcription Factors, HLF, FTF, and E4BP4, Controlling Hepatitis B Virus Enhancer II

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Firefly luciferase gene: structure and expression in mammalian cells.

1987 • 3,088 citations

HEPATOCELLULAR CARCINOMA AND HEPATITIS B VIRUS

1981 • 2,891 citations

Replication of the genome of a hepatitis B-like virus by reverse transcription of an RNA intermediate

1982 • 1,429 citations

The hepatitis B virus

1985 • 1,219 citations

THE MOLECULAR BIOLOGY OF THE HEPATITIS B VIRUSES

1987 • 1,046 citations

Firefly Luciferase Gene: Structure and Expression in Mammalian Cells

1987 • 924 citations

CCAAT/enhancer binding protein activates the promoter of the serum albumin gene in cultured hepatoma cells.

1989 • 488 citations

The role of envelope proteins in hepatitis B virus assembly.

1991 • 389 citations

Production of hepatitis B virus by a differentiated human hepatoma cell line after transfection with cloned circular HBV DNA

1986 • 350 citations

Replication strategy of human hepatitis B virus

1987 • 314 citations

Fusion of the Leucine Zipper Gene HLF to the E2A Gene in Human Acute B-Lineage Leukemia

1992 • 290 citations

A human hepatitis B viral enhancer element.

1985 • 286 citations

HNF-1, a member of a novel class of dimerizing homeodomain proteins.

1991 • 286 citations

Hepatitis B virus (HBV) particles are produced in a cell culture system by transient expression of transfected HBV DNA.

1987 • 248 citations

Signals regulating hepatitis B surface antigen transcription

1983 • 246 citations

The α₁-Fetoprotein Locus Is Activated by a Nuclear Receptor of the Drosophila FTZ-F1 Family

1996 • 242 citations

Hlf, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic leukemia.

1992 • 234 citations

Stable expression and replication of hepatitis B virus genome in an integrated state in a human hepatoma cell line transfected with the cloned viral DNA.

1987 • 201 citations

Transcriptional regulation of precore and pregenomic RNAs of hepatitis B virus

1992 • 196 citations

Transcriptional repression by a novel member of the bZIP family of transcription factors.

1992 • 182 citations

Production of hepatitis B virus in vitro by transient expression of cloned HBV DNA in a hepatoma cell line.

1987 • 176 citations

A Liver-Specific Enhancer in the Core Promoter Region of Human Hepatitis B Virus

1989 • 168 citations

Hepatitis B virus transcription in the infected liver.

1984 • 167 citations

Members of the nuclear receptor superfamily regulate transcription from the hepatitis B virus nucleocapsid promoter

1997 • 164 citations

Multiple liver-specific factors bind to the hepatitis B virus core/pregenomic promoter: trans-activation and repression by CCAAT/enhancer binding protein.

1990 • 162 citations

Avian retroviral long terminal repeats bind CCAAT/enhancer-binding protein.

1989 • 160 citations

Pivotal role for the NFIL3/E4BP4 transcription factor in interleukin 3-mediated survival of pro-B lymphocytes

1997 • 140 citations

Expression of the hepatitis B virus X gene in mammalian cells.

1987 • 131 citations

Molecular Cloning and Characterization of NF-IL3A, a Transcriptional Activator of the Human Interleukin-3 Promoter

1995 • 129 citations

Liver-specific expression of hepatitis B virus is determined by the combined action of the core gene promoter and the enhancer

1989 • 125 citations

Transcriptional factor C/EBP binds to and transactivates the enhancer element II of the hepatitis B virus

1991 • 115 citations

Hepatitis B virus (HBV) promoters are regulated by the HBV enhancer in a tissue-specific manner

1989 • 115 citations

The genome of hepatitis B virus contains a second enhancer: cooperation of two elements within this enhancer is required for its function

1990 • 114 citations

Cloning and Characterization of a Novel Human Hepatocyte Transcription Factor, hB1F, Which Binds and Activates Enhancer II of Hepatitis B Virus

1998 • 113 citations

Identification of a promoter element located upstream from the hepatitis B virus X gene.

1987 • 103 citations

The human hepatitis B virus enhancer requires trans-acting cellular factor(s) for activity.

1986 • 99 citations

Regulation of hepatitis B virus gene expression by its two enhancers.

1992 • 96 citations

Transcription of the hepatitis B surface antigen gene in cultured murine cells initiates within the presurface region

1984 • 96 citations

A novel expression selection approach allows precise mapping of the hepatitis B virus enhancer

1985 • 95 citations

Differential regulation of the pre-C and pregenomic promoters of human hepatitis B virus by members of the nuclear receptor superfamily

1997 • 94 citations

Hepatocyte-Specific Expression of the Hepatitis B Virus Core Promoter Depends on Both Positive and Negative Regulation

1993 • 89 citations

A new enhancer element, ENII, identified in the X gene of hepatitis B virus

1990 • 88 citations

Transcriptional repression by the human bZIP factor E4BP4: definition of a minimal repression domain

1994 • 88 citations

Promoters for synthesis of the pre-C and pregenomic mRNAs of human hepatitis B virus are genetically distinct and differentially regulated

1996 • 86 citations

Transcriptional control elements of hepatitis B surface antigen gene.

1986 • 86 citations

Overlapping initiator and TATA box functions in the basal core promoter of hepatitis B virus

1995 • 83 citations

DNA-binding specificity and trans-activating potential of the leukemia-associated E2A-hepatic leukemia factor fusion protein.

1994 • 71 citations

Avian Retroviral Long Terminal Repeats Bind CCAAT/Enhancer-Binding Protein

1989 • 71 citations

DNA-Binding Specificity of the PAR Basic Leucine Zipper Protein VBP Partially Overlaps Those of the C/EBP and CREB/ATF Families and Is Influenced by Domains That Flank the Core Basic Region

1995 • 68 citations

HNF3 Binds and Activates the Second Enhancer, ENII, of Hepatitis B Virus

1995 • 68 citations

Functional Analysis of Developmentally Regulated Chromatin-Hypersensitive Domains Carrying the α₁-Fetoprotein Gene Promoter and the Albumin/α₁-Fetoprotein Intergenic Enhancer

1993 • 67 citations

Properties of the human hepatitis B virus enhancer: position effects and cell-type nonspecificity

1988 • 67 citations

Identification of a promoter region for 3.6-kilobase mRNA of hepatitis B virus and specific cellular binding protein

1989 • 66 citations

Characterization of functional Sp1 transcription factor binding sites in the hepatitis B virus nucleocapsid promoter

1993 • 63 citations

Characterization of a Functional Hepatocyte Nuclear Factor 3 Binding Site in the Hepatitis B Virus Nucleocapsid Promoter

1995 • 61 citations

DNA-binding and transcriptional regulatory properties of hepatic leukemia factor (HLF) and the t(17;19) acute lymphoblastic leukemia chimera E2A-HLF.

1994 • 59 citations

C/EBP-like proteins binding to the functional box-alpha and box-beta of the second enhancer of hepatitis B virus.

1991 • 52 citations

The Human Hepatitis B Virus Enhancer Requires trans-Acting Cellular Factor(s) for Activity

1986 • 48 citations

Differentiated liver cell specificity of the second enhancer of hepatitis B virus

1993 • 45 citations

Identification of a Promoter Element Located Upstream from the Hepatitis B Virus X Gene

1987 • 44 citations

The Chimeric E2A-HLF Transcription Factor Abrogates p53-Induced Apoptosis in Myeloid Leukemia Cells

1998 • 39 citations

Repression of enhancer II activity by a negative regulatory element in the hepatitis B virus genome

1994 • 39 citations

Protein-protein interaction between the transcriptional repressor E4BP4 and the TBP-binding protein Dr1

1996 • 37 citations

Transcriptional Repression of Human Hepatitis B Virus Genes by a bZIP Family Member, E4BP4

1999 • 34 citations

HNF1 is critical for the liver-specific function of HBV enhancer II

1998 • 33 citations

Transcriptional Repression by a Novel Member of the bZIP Family of Transcription Factors

1992 • 29 citations

Binding of the Ets Factor GA-Binding Protein to an Upstream Site in the Factor IX Promoter Is a Critical Event in Transactivation

1996 • 28 citations

The gene S promoter of hepatitis B virus confers constitutive gene expression

1983 • 25 citations

Characterization of human E4BP4, a phosphorylated bZIP factor

1995 • 23 citations

C/EBP-Like Proteins Binding to the Functional Box-α and Box-β of the Second Enhancer of Hepatitis B Virus

1991 • 22 citations

DNA-Binding and Transcriptional Regulatory Properties of Hepatic Leukemia Factor (HLF) and the t(17;19) Acute Lymphoblastic Leukemia Chimera E2A-HLF

1994 • 15 citations

DNA-Binding Specificity and trans-Activating Potential of the Leukemia-Associated E2A-Hepatic Leukemia Factor Fusion Protein

1994 • 13 citations