DNA-binding and transcriptional regulatory properties of hepatic leukemia factor (HLF) and the t(17;19) acute lymphoblastic leukemia chimera E2A-HLF.

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1987 • 1,792 citations

Scissors-Grip Model for DNA Recognition by a Family of Leucine Zipper Proteins

1989 • 996 citations

Differences and Similarities in DNA-Binding Preferences of MyoD and E2A Protein Complexes Revealed by Binding Site Selection

1990 • 957 citations

Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma

1993 • 884 citations

A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B all

1990 • 726 citations

Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor

1990 • 692 citations

Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.

1993 • 560 citations

Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma

1993 • 551 citations

Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma

1993 • 546 citations

EWS and ATF-1 gene fusion induced by t(12;22) translocation in malignant melanoma of soft parts

1993 • 491 citations

DBP, a liver-enriched transcriptional activator, is expressed late in ontogeny and its tissue specificity is determined posttranscriptionally

1990 • 410 citations

Dimerization specificity of the leucine zipper-containing bZIP motif on DNA binding: prediction and rational design.

1993 • 335 citations

Circadian transcription of the cholesterol 7 alpha hydroxylase gene may involve the liver-enriched bZIP protein DBP.

1993 • 293 citations

Fusion of the Leucine Zipper Gene HLF to the E2A Gene in Human Acute B-Lineage Leukemia

1992 • 290 citations

PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1.

1991 • 280 citations

TEF, a transcription factor expressed specifically in the anterior pituitary during embryogenesis, defines a new class of leucine zipper proteins.

1991 • 246 citations

Hlf, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic leukemia.

1992 • 234 citations

The t(1;19)(q23;p13) results in consistent fusion of E2A and PBX1 coding sequences in acute lymphoblastic leukemias

1991 • 218 citations

Expression of the liver-enriched transcriptional activator protein DBP follows a stringent circadian rhythm

1990 • 218 citations

Oncogenic conversion of transcription factors by chromosomal translocations

1991 • 209 citations

Synergistic activation of the chicken mim-1 gene by v-myb and C/EBP transcription factors.

1993 • 198 citations

The NF-M transcription factor is related to C/EBP beta and plays a role in signal transduction, differentiation and leukemogenesis of avian myelomonocytic cells.

1993 • 195 citations

Transcriptional repression by a novel member of the bZIP family of transcription factors.

1992 • 182 citations

Transcriptional regulation by Fos and Jun in vitro: interaction among multiple activator and regulatory domains.

1991 • 175 citations

A New Transcriptional-Activation Motif Restricted to a Class of Helix-Loop-Helix Proteins Is Functionally Conserved in Both Yeast and Mammalian Cells

1993 • 158 citations

Pbx1 is converted into a transcriptional activator upon acquiring the N-terminal region of E2A in pre-B-cell acute lymphoblastoid leukemia.

1993 • 138 citations

The E2A gene product contains two separable and functionally distinct transcription activation domains.

1993 • 138 citations

Identification of C/EBP basic region residues involved in DNA sequence recognition and half-site spacing preference.

1993 • 119 citations

PBX2 and PBX3, New Homeobox Genes with Extensive Homology to the Human Proto-Oncogene PBX1

1991 • 108 citations

Fusion with E2A alters the transcriptional properties of the homeodomain protein PBX1 in t(1;19) leukemias.

1994 • 94 citations

Chicken vitellogenin gene-binding protein, a leucine zipper transcription factor that binds to an important control element in the chicken vitellogenin II promoter, is related to rat DBP.

1991 • 89 citations

A new transcriptional-activation motif restricted to a class of helix-loop-helix proteins is functionally conserved in both yeast and mammalian cells.

1993 • 72 citations

Two types of genomic rearrangements create alternative E2A-HLF fusion proteins in t(17;19)-ALL

1994 • 65 citations

Synergy between transcription factors DBP and C/EBP compensates for a haemophilia B Leyden factor IX mutation

1993 • 52 citations

The C/EBP family of transcriptional activators is functionally important for Ig VH promoter activity in vivo and in vitro.

1992 • 38 citations

Identification of C/EBP Basic Region Residues Involved in DNA Sequence Recognition and Half-Site Spacing Preference

1993 • 38 citations

Role of the Liver-Enriched Transcription Factor DBP in Expression of the Cytochrome P450 CYP2C6 Gene

1992 • 36 citations

Transcriptional Repression by a Novel Member of the bZIP Family of Transcription Factors

1992 • 29 citations

30 Dangerous Liaisons: Fos and Jun, Oncogenic Transcription Factors

1992 • 25 citations

Transcriptional Regulation by Fos and Jun In Vitro: Interaction among Multiple Activator and Regulatory Domains

1991 • 24 citations

Role of the liver-enriched transcription factor DBP in expression of the cytochrome P450 CYP2C6 gene.

1992 • 24 citations

Chicken Vitellogenin Gene-Binding Protein, a Leucine Zipper Transcription Factor That Binds to an Important Control Element in the Chicken Vitellogenin II Promoter, Is Related to Rat DBP

1991 • 22 citations

Transcriptional Regulation

2017 • 18 citations

1 Transcriptional Regulation: Elegance in Design and Discovery

1992 • 8 citations

Deleted Work

1955 • 0 citations