Destruction of U2, U4, or U6 small nuclear RNA blocks Trans splicing in trypanosome cells

A catalogue of splice junction sequences

1982 • 3,861 citations

SPLICING OF MESSENGER RNA PRECURSORS

1986 • 1,233 citations

Capping of eucaryotic mRNAs

1976 • 1,141 citations

Splicing of Messenger RNA Precursors

1987 • 919 citations

Splicing of Messenger RNA Precursors

1984 • 874 citations

PRE-mRNA SPLICING

1986 • 673 citations

U2 as well as U1 small nuclear ribonucleoproteins are involved in premessenger RNA splicing

1985 • 568 citations

5′-Terminal structure and mRNA stability

1977 • 542 citations

Evidence for Trans splicing in trypanosomes

1986 • 486 citations

5'-terminal cap structure in eucaryotic messenger ribonucleic acids

1980 • 463 citations

Multiple factors including the small nuclear ribonucleoproteins U1 and U2 are necessary for Pre-mRNA splicing in vitro

1985 • 442 citations

DISCONTINUOUS TRANSCRIPTION AND ANTIGENIC VARIATION IN TRYPANOSOMES

1986 • 418 citations

The 5′ terminus of the RNA moiety of U1 small nuclear ribonucleoprotein particles is required for the splicing of messenger RNA precursors

1984 • 404 citations

Identification of a novel Y branch structure as an intermediate in trypanosome mRNA processing: Evidence for Trans splicing

1986 • 354 citations

An RNA Processing Activity That Debranches RNA Lariats

1985 • 300 citations

Transcripts coding for variant surface glycoproteins of Trypanosoma brucei have a short, identical exon at their 5′ end

1982 • 243 citations

Pre-mRNA splicing in vitro requires intact U4/U6 small nuclear ribonucleoprotein

1986 • 222 citations

Trans splicing involves a novel form of small nuclear ribonucleoprotein particles

1988 • 210 citations

Apparent discontinuous transcription of Trypanosoma brucei variant surface antigen genes

1984 • 193 citations

U1, U2, and U4/U6 small nuclear ribonucleoproteins are required for in vitro splicing but not polyadenylation

1986 • 192 citations

RNA splicing is required to make the messenger RNA for a variant surface antigen in trypanosomes

1982 • 183 citations

Trypanosome mRNAs have unusual "cap 4" structures acquired by addition of a spliced leader.

1987 • 179 citations

Importance of 5'-terminal blocking structure to stabilize mRNA in eukaryotic protein synthesis.

1977 • 179 citations

Identification of a small rna containing the trypanosome spliced leader: A donor of shared 5′ sequences of trypanosomatid mRNAs?

1984 • 176 citations

Calmodulin genes in trypanosomes are tandemly repeated and produce multiple mRNAs with a common 5' leader sequence.

1985 • 162 citations

Discontinuous synthesis of mRNA in trypanosomes.

1984 • 145 citations

Polygene transcripts are precursors to calmodulin mRNAs in trypanosomes.

1988 • 143 citations

Isolation and sequence of four small nuclear U RNA genes of Trypanosoma brucei subsp. brucei: identification of the U2, U4, and U6 RNA analogs.

1989 • 122 citations

ANTIGENIC VARIATION IN AFRICAN TRYPANOSOMES

1985 • 121 citations

Structure and transcription of the actin gene of Trypanosoma brucei.

1988 • 107 citations

Functions of the 5′‐terminal m⁷G cap in eukaryotic mRNA

1978 • 99 citations

Splicing pathways of SV40 mRNAs in X. laevis oocytes differ in their requirements for snRNPs

1984 • 98 citations

Mature mRNAs ofTrypanosoma bruceipossess a 5′ cap acquired by discontinuous RNA synthesis

1985 • 95 citations

In vivo labelling of intermediates in the discontinuous synthesis of mRNAs in Trypanosoma brucei.

1987 • 92 citations

A 5' spliced leader is added in trans to both alpha- and beta-tubulin transcripts in Trypanosoma brucei.

1985 • 88 citations

The U2 RNA analogue ofTrypanosoma brucei gambiense: implications for a splicing mechanism in trypanosomes

1986 • 86 citations

Direct analysis of the mini-exon donor RNA ofTrypanosoma brucei: detection of a novel cap structure also present in messenger RNA

1987 • 73 citations

Splicing of Xenopus laevis ribosomal protein RNAs is inhibited in vivo by antisera to ribonucleoproteins containing U1 small nuclear RNA

1984 • 54 citations

Trypanosome trans-splicing utilizes 2′-5′ branches and a corresponding debranching activity.

1988 • 37 citations

Conserved sequences in the U2 snRNA-encoding genes of Kinetoplastida do not include the putative branchpoint recognition region

1990 • 35 citations

The U6 small nuclear RNA fromTrypanosoma brucei

1988 • 31 citations

The cap of both miniexon-derived RNA and mRNA of trypanosomes is 7-methylguanosine.

1988 • 28 citations