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Functions of the 5′‐terminal m7G cap in eukaryotic mRNA

Data up to Jan 2025

Published1978
Citations99
References109

Total Citations Per Year

Abstract

References (109)

The 3′-Terminal Sequence of Escherichia coli 16S Ribosomal RNA: Complementarity to Nonsense Triplets and Ribosome Binding Sites

1974 • 3,603 citations

Capping of eucaryotic mRNAs

1976 • 1,141 citations

How ribosomes select initiator regions in mRNA: base pair formation between the 3' terminus of 16S rRNA and the mRNA during initiation of protein synthesis in Escherichia coli.

1975 • 690 citations

5′-Terminal structure and mRNA stability

1977 • 542 citations

5′-Terminal 7-methylguanosine in eukaryotic mRNA is required for translation

1975 • 481 citations

Translational Control of Protein Synthesis

1976 • 456 citations

Sequence of chicken ovalbumin mRNA

1978 • 438 citations

Conservation of the primary structure at the 3′ end of 18S rRNA from eucaryotic cells

1978 • 427 citations

Reovirus messenger RNA contains a methylated, blocked 5'-terminal structure: m-7G(5')ppp(5')G-MpCp-.

1975 • 352 citations

Initiation of mammalian protein synthesis

1977 • 337 citations

Methylated nucleotides block 5'-terminus of vaccinia virus messenger RNA.

1975 • 308 citations

A blocked structure at the 5′ terminus of mRNA from cytoplasmic polyhedrosis virus

1975 • 297 citations

Methylation-dependent translation of viral messenger RNAs in vitro.

1975 • 288 citations

Sequences containing methylated nucleotides at the 5′ termini of messenger RNAs: Possible implications for processing

1974 • 275 citations

The 5' end of poliovirus mRNA is not capped with m7G(5')ppp(5')Np.

1976 • 271 citations

The 5′ terminal structure of the methylated mRNA synthesized in vitro by vesicular stomatitis virus

1975 • 252 citations

5'-terminal structure of poliovirus polyribosomal RNA is pUp.

1976 • 247 citations

Ribosome binding to reovirus mRNA in protein synthesis requires 5′ terminal 7-methylguanosine

1975 • 241 citations

Comparison of methylated sequences in messenger RNA and heterogeneous nuclear RNA from mouse L cells

1977 • 230 citations

Inhibition of initiation of protein synthesis by 7-methylguanosine-5'-monophosphate.

1976 • 222 citations

Nucleotide sequence of a viral RNA fragment that binds to eukaryotic ribosomes

1975 • 186 citations

Importance of 5'-terminal blocking structure to stabilize mRNA in eukaryotic protein synthesis.

1977 • 179 citations

End labeling of enzymatically decapped mRNA

1977 • 175 citations

Evidence for role of m7G5′-phosphate group in recognition of eukaryotic mRNA by initiation factor IF-M3

1976 • 161 citations

Inhibition of the transition of a 40S ribosome–Met-tRNAiMet complex to an 80S ribosome–Met-tRNAiMet complex by 7-methylguanosine-5′-phosphate

1976 • 156 citations

Inhibition of protein synthesis by Cl-.

1977 • 142 citations

Competition between cellular and viral mRNAs in vitro is regulated by a messenger discriminatory initiation factor.

1976 • 138 citations

Kinetics of formation of 5′ terminal caps in mRNA

1976 • 134 citations

Translation in vitro of vesicular stomatitis virus mRNA lacking 5′-terminal 7-methylguanosine

1976 • 131 citations

Identification of features in 5′ terminal fragments from reovirus mRNA which are important for ribosome binding

1978 • 130 citations

“Methylation-coupled” transcription by virus-associated transcriptase of cytoplasmic polyhedrosis virus containing double-stranded RNA

1974 • 124 citations

International symposium on protein synthesis Summary of Fogarty Center‐NIH Workshop held in Bethesda, Maryland on 18–20 October, 1976

1977 • 123 citations

Relative importance of 7-methylguanosine in ribosome binding and translation of vesicular stomatitis virus mRNA in wheat germ and reticulocyte cell-free systems.

1977 • 121 citations

Influence of 5'-terminal m7G and 2'-O-methylated residues on messenger ribonucleic acid binding to ribosomes

1976 • 120 citations

Structural difference between the 5' termini of viral and cellular mRNA in poliovirus-infected cells: possible basis for the inhibition of host protein synthesis

1976 • 120 citations

Heterogneeous 5'-terminal structures occur on vesicular stomatitis virus mRNAs.

1975 • 119 citations

Novel initiation of RNA synthesis in vitro by vesicular stomatitis virus

1975 • 119 citations

A protein binding the methylated 5'-terminal sequence, m7GpppN, of eukaryotic messenger RNA.

1976 • 111 citations

Translation of Virus mRNA: Synthesis of Bacteriophage Qβ Proteins in a Cell-Free Extract from Wheat Embryo

1973 • 107 citations

Characterization of ribosome-protected fragments from reovirus messenger RNA.

1976 • 106 citations

Nucleotide sequences of 5′-terminal ribosome-protected initiation regions from two reovirus messages

1977 • 104 citations

Translational discrimination of ‘capped’ and ‘non‐capped’ mRNAS: inhibition by a series of chemical analogs of m7 GpppX

1976 • 103 citations

Reovirus mRNA can be covalently crosslinked via the 5' cap to proteins in initiation complexes.

1977 • 102 citations

Influence of 5'-terminal cap structure on the initiation of translation of vaccinia virus mRNA.

1978 • 101 citations

Formation of the guanylylated and methylated 5′-terminus of vaccinia virus mRNA

1976 • 95 citations

Translational control: recognition of the methylated 5' end and an internal sequence in eukaryotic mRNA by the initiation factor that binds methionyl-tRNAfMet.

1978 • 93 citations

5'-Terminal 7-methylguanosine and mRNA function: influence of potassium concentration on translation in vitro.

1977 • 89 citations

Sequences of two 5′-terminal ribosome-protected fragments from reovirus messenger RNAs

1977 • 86 citations

A modified structure at the 5′‐terminus of mRNA of vaccinia virus

1975 • 85 citations

Complete nucleotide sequence of the 5′ noncoding region of human α- and β-globin mRNA

1977 • 81 citations

Effect of 5′-terminal structure and base composition on polyribonucleotide binding to ribosomes

1976 • 80 citations

Characterization of the ribosome-protected regions of 125I-labelled rabbit globin messenger RNA

1976 • 79 citations

“Pretranscriptional capping” in the biosynthesis of cytoplasmic polyhedrosis virus mRNA

1978 • 78 citations

The effect of “cap” analogs on reovirus mRNA binding to wheat germ ribosomes. Evidence for enhancement of ribosomal binding via a preferred cap conformation.

1978 • 78 citations

5′-Terminal nucleotide sequences of polio virus polyribosomal RNA and virion RNA are identical

1977 • 76 citations

Sequences and properties of two ribosome binding sites from the small size class of reovirus messenger RNA.

1977 • 76 citations

Giant heterogeneous polyadenylic acid on vesicular stomatitis virus mRNA synthesized in vitro in the presence of S-adenosylhomocysteine

1977 • 75 citations

mRNA methylation and protein synthesis in extracts from embryos of brine shrimp, Artemia salina.

1975 • 75 citations

Nucleotide Sequence at the 5' Extremity of Tobacco-Mosaic-Virus RNA. 1. The Noncoding Region (Nucleotides 1-68)

1978 • 74 citations

Utilization of the guanylyltransferase and methyltransferases of vaccinia virus to modify and identify the 5′-terminals of heterologous RNA species

1977 • 73 citations

Terminal heterogeneity at both ends of the satellite tobacco necrosis virus ribonucleic acid

1971 • 73 citations

Cowpea mosaic virus RNAs have neither m7GpppN … nor mono-, di- or triphosphates at their 5′ ends

1977 • 70 citations

Enzyme cleaving the 5′‐terminal methylated blocked structure of messenger RNA

1976 • 70 citations

Nucleotide sequence of 5' terminus of alfalfa mosaic virus RNA 4 leading into coat protein cistron.

1977 • 70 citations

A relation between inhibition of protein synthesis and conformation of 5′-phosphorylated 7-methylguanosine derivatives

1977 • 67 citations

Differential synthesis of blocked and unblocked 5'-termini in reovirus mRNA: effect of pyrophosphate and pyrophosphatase.

1976 • 66 citations

Importance of initiation factor preparations in the translation of reovirus and globin mRNAs lacking a 5'-terminal 7-methylguanosine

1977 • 64 citations

Di- and trimethylated congeners of 7-methylguanine in Sindbis virus mRNA

1976 • 62 citations

7-Methyl-guanosine and efficiency of RNA translation

1976 • 62 citations

Influence of potassium salt concentration and temperature on inhibition of mRNA translation by 7-methylguanosine5'-monophosphate.

1978 • 60 citations

Cell-free translation of messenger RNA from oocytes of Xenopus laevis

1976 • 59 citations

Structure–function relationship of 5′ non-coding sequence of rabbit α- and β-globin mRNA

1977 • 57 citations

Removal of 5′-terminal m7G from eukaryotic mRNAs by potato nucleotide pyrophosphatase and its effect on translation

1977 • 57 citations

Translation of bacteriophage R17 and Qβ RNA in a mammalian cell-free system

1973 • 52 citations

Translation of tobacco necrosis virus and its satellite in a cell-free wheat germ system.

1977 • 51 citations

Inhibition of HeLa cell messenger RNA translation by 7-methylguanosine 5'-monophosphate.

1976 • 50 citations

Translation of Bacteriophage Qβ RNA by Cytoplasmic Extracts of Mammalian Cells

1973 • 48 citations

Characterization and translation of methylated and unmethylated vesicular stomatitis virus mRNA synthesized in vitro by ribonucleoprotein particles from vesicular stomatitis virus-infected L cells

1976 • 48 citations

Dependence on potassium concentration of the inhibition of the translation of messenger ribonucleic acid by 7-methylguanosine 5'-phosphate

1977 • 48 citations

Translation of satellite tobacco necrosis virus ribonucleic acid by an in vitro system from wheat germ

1976 • 45 citations

Characteristics of a Coupled Cell‐Free Transcription and Translation System Directed by Vaccinia Cores

1978 • 44 citations

Identity of the 5′-Terminal RNA Nucleotide Sequence of the Satellite Tobacco Necrosis Virus and Its Helper Virus: Possible Role of the 5′-Terminus in the Recognition by Virus-Specific RNA Replicase

1970 • 43 citations

Nucleotide sequences of ribosome recgonition sites in messenger RNAs of vesicular stomatitis virus.

1977 • 42 citations

Translation of Bacteriophage Qβ Messenger RNA in a Murine Krebs 2 Ascites Tumor Cell-Free System

1972 • 42 citations

Absence of 5' terminal capping in encephalomyocarditis virus RNA

1976 • 41 citations

Inactivation of parathyroid hormone mRNA by treatment with periodate and aniline

1976 • 37 citations

Biosynthesis of reovirus-specified polypeptides

1977 • 37 citations

Initiator regions from the small size class of reovirus messenger RNA protected by rabbit reticulocyte ribosomes.

1977 • 37 citations

The Isometric Single-Stranded DNA Phages

1977 • 37 citations

Translation of RNA from unfertilised sea urchin eggs does not require methylation and is inhibited by 7-methylguanosine-5′-monophosphate

1976 • 35 citations

m7G5′ppp5′GmpCpUp at the 5′ terminus of reovirus messenger RNA

1975 • 33 citations

5′‐Capping Structures of Artemia salina mRNA and the Translational Inhibition by Cap Analogs

1976 • 31 citations

Translation of a specific mRNA from Escherichiacoli in a eukaryotic cell-free system

1976 • 30 citations

The process of formation of the 5′‐terminal modified structure in messenger RNA of cytoplasmic polyhedrosis virus

1976 • 29 citations

Bacteriophage T3 and T7 early RNAs are translated by eukaryotic 80S ribosomes: active phage T3 coded S-adenosylmethionine cleaving enzyme is synthesized.

1976 • 29 citations

In vitro synthesis of RNA containing 5′-terminal structure 7mG(5′)ppp(5′)Apm… by purified wound tumor virus

1977 • 29 citations

Effects of U1 nuclear RNA on translation of messenger RNA

1977 • 28 citations

Interaction of rabbit reticulocyte ribosomes with bacteriophage f1 mRNA and of Escherichia coli ribosomes with rabbit globin mRNA

1977 • 25 citations

Inhibition of noncapped mRNA translation by the cap analogue, 7-methylguanosine-5′-phosphate

1978 • 23 citations

Spatial configuration of mRNA 5′-terminus

1977 • 23 citations

Non-methylated guanosine as the 5′ terminus of capped mRNA from insect oocytes

1976 • 21 citations

Effect of 7‐methylguanosine‐5′‐phosphate on rabbit globin synthesis

1976 • 20 citations

Differential inhibition with partially purified and endogenous rabbit reticulocyte globin mRNA by 7-methylguanosine 5′-monophosphate

1977 • 18 citations

Methylation of high-molecular-weight subunit RNA of feline leukemia virus

1976 • 17 citations

Inhibition of ovalbumin mRNA translation by 7-methylguanosine-5′-phosphate

1976 • 16 citations

Ribosome binding of capped satellite tobacco necrosis virus RNA

1977 • 15 citations

Enzymatic cleavage of m7 GDP from eucaryotic mRNA

1976 • 12 citations

Effect of 5′-Terminal Structures on the Binding of Ribopolymers to Eukaryotic Ribosomes

1977 • 8 citations

Analysis of cytoplasmic RNA and polyribosmomes from feline leukemia virus-infected cells

1978 • 7 citations

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Functions of the 5′‐terminal m7G cap in eukaryotic mRNA (1978) – FEBS Letters | Metascience Observatory Explorer