Differential signalling by muscarinic receptors in smooth muscle: m2-mediated inactivation of myosin light chain kinase via Gi3, Cdc42/Rac1 and p21-activated kinase 1 pathway, and m3-mediated MLC20 (20 kDa regulatory light chain of myosin II) phosphorylation via Rho-associated kinase/myosin phosphatase targeting subunit 1 and protein kinase C/CPI-17 pathway

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1997 • 2,847 citations

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1996 • 2,843 citations

Signal transduction and regulation in smooth muscle

1994 • 1,915 citations

Signal transduction by G‐proteins, Rho‐kinase and protein phosphatase to smooth muscle and non‐muscle myosin II

2000 • 1,219 citations

Direct Stimulation of the Guanine Nucleotide Exchange Activity of p115 RhoGEF by Gα ₁₃

1998 • 765 citations

Mechanisms of smooth muscle contraction

1996 • 748 citations

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2001 • 743 citations

Inhibition of Myosin Light Chain Kinase by p21-Activated Kinase

1999 • 592 citations

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2001 • 553 citations

Phospholipase D: enzymology, mechanisms of regulation, and function

1997 • 405 citations

Agonists Trigger G Protein-mediated Activation of the CPI-17 Inhibitor Phosphoprotein of Myosin Light Chain Phosphatase to Enhance Vascular Smooth Muscle Contractility

2000 • 336 citations

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1991 • 319 citations

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1996 • 280 citations

Activation of Cdc42, Rac, PAK, and Rho-Kinase in Response to Hepatocyte Growth Factor Differentially Regulates Epithelial Cell Colony Spreading and Dissociation

2000 • 276 citations

Activation of rat liver phospholipase D by the small GTP-binding protein RhoA

1994 • 265 citations

Ca2+-independent Smooth Muscle Contraction

2001 • 252 citations

Molecular cloning of a novel phosphorylation‐dependent inhibitory protein of protein phosphatase‐1 (CPI17) in smooth muscle: its specific localization in smooth muscle¹

1997 • 247 citations

Expression of CPI‐17 and myosin phosphatase correlates with Ca²⁺ sensitivity of protein kinase C‐induced contraction in rabbit smooth muscle

2001 • 238 citations

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2000 • 220 citations

Translocation of rhoA Associated with Ca2+ Sensitization of Smooth Muscle

1997 • 218 citations

Identification of the endogenous smooth muscle myosin phosphatase-associated kinase

2001 • 207 citations

The effects of the Rho‐kinase inhibitor Y‐27632 on arachidonic acid‐, GTPγS‐, and phorbol ester‐induced Ca²⁺‐sensitization of smooth muscle

1998 • 199 citations

Histamine-induced Vasoconstriction Involves Phosphorylation of a Specific Inhibitor Protein for Myosin Phosphatase by Protein Kinase C α and δ Isoforms

2001 • 195 citations

Inhibition of Rho‐associated kinase blocks agonist‐induced Ca²⁺ sensitization of myosin phosphorylation and force in guinea‐pig ileum

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1994 • 182 citations

Zipper-interacting Protein Kinase Induces Ca2+-free Smooth Muscle Contraction via Myosin Light Chain Phosphorylation

2001 • 176 citations

Ca(2+)-dependent phosphorylation of myosin light chain kinase decreases the Ca2+ sensitivity of light chain phosphorylation within smooth muscle cells

1994 • 176 citations

Inhibition of RhoA Translocation and Calcium Sensitization by In Vivo ADP-Ribosylation with the Chimeric Toxin DC3B

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Ca²⁺‐independent phosphorylation of myosin in rat caudal artery and chicken gizzard myofilaments

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GTP gamma S-dependent regulation of smooth muscle contractile elements

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Somatostatin Receptor-mediated Signaling in Smooth Muscle

1996 • 129 citations

Opioid mu, delta, and kappa receptor-induced activation of phospholipase C-beta 3 and inhibition of adenylyl cyclase is mediated by Gi2 and G(o) in smooth muscle.

1996 • 124 citations

Dual Ser and Thr phosphorylation of CPI‐17, an inhibitor of myosin phosphatase, by MYPT‐associated kinase

2001 • 112 citations

Smooth muscle protein kinase C

1994 • 108 citations

Epsilon-isoenzyme of protein kinase C induces a Ca(2+)-independent contraction in vascular smooth muscle

1996 • 102 citations

Coexpression of Ligand-gated P2X and G Protein-coupled P2Y Receptors in Smooth Muscle

1998 • 100 citations

Identification of Trimeric Myosin Phosphatase (PP1M) as a Target for a Novel PKC-Potentiated Protein Phosphatase-1 Inhibitory Protein (CPI17) in Porcine Aorta Smooth Muscle

1999 • 91 citations

Differential Coupling of Muscarinic m2 and m3 Receptors to Adenylyl Cyclases V/VI in Smooth Muscle

1997 • 83 citations

Coupling of the Insulin-like Growth Factor-I Receptor Tyrosine Kinase to Gi2 in Human Intestinal Smooth Muscle

2001 • 82 citations

Clostridium difficile toxin B inhibits carbachol‐induced force and myosin light chain phosphorylation in guinea‐pig smooth muscle: role of Rho proteins

1998 • 79 citations

Adenosine A1 receptor-mediated activation of phospholipase C-beta 3 in intestinal muscle: dual requirement for alpha and beta gamma subunits of Gi3.

1995 • 75 citations

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1986 • 67 citations

Sustained muscle contraction induced by agonists, growth factors, and Ca²⁺mediated by distinct PKC isozymes

2000 • 62 citations

Erk1/2- and p38 MAP kinase-dependent phosphorylation and activation of cPLA₂by m3 and m2 receptors

2003 • 59 citations

Coupling of M2 Muscarinic Receptors to Membrane Ion Channels via Phosphoinositide 3-Kinase γ and Atypical Protein Kinase C

1999 • 57 citations

Rho-dependent Agonist-induced Spatio-temporal Change in Myosin Phosphorylation in Smooth Muscle Cells

2002 • 51 citations

Phosphoinositide metabolism in intestinal smooth muscle: preferential production of Ins(1,4,5)P3 in circular muscle cells

1991 • 42 citations

Identification of Human CPI-17, an Inhibitory Phosphoprotein for Myosin Phosphatase

2001 • 39 citations

Agonist-mediated activation of phosphatidylcholine-specific phospholipase C and D in intestinal smooth muscle.

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The involvement of protein kinase C in myosin phosphorylation and force development in rat tail arterial smooth muscle

2000 • 23 citations

The involvement of protein kinase C in myosin phosphorylation and force development in rat tail arterial smooth muscle

2000 • 8 citations