Direct effects of T‐bet and MHC class I expression, but not STAT1, on peripheral NK cell maturation

A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment

2000 • 3,456 citations

Biology of Natural Killer Cells

1989 • 2,970 citations

RAG-1-deficient mice have no mature B and T lymphocytes

1992 • 2,859 citations

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1992 • 2,618 citations

Targeted Disruption of the Mouse Stat1 Gene Results in Compromised Innate Immunity to Viral Disease

1996 • 1,560 citations

Distinct Effects of T-bet in T _H 1 Lineage Commitment and IFN-γ Production in CD4 and CD8 T Cells

2002 • 1,169 citations

Molecular Mechanisms RegulatinG Th1 Immune Responses

2003 • 1,005 citations

T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells

2002 • 985 citations

Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

1995 • 881 citations

IL-15Rα Recycles and Presents IL-15 In trans to Neighboring Cells

2002 • 877 citations

T-bet is rapidly induced by interferon-γ in lymphoid and myeloid cells

2001 • 743 citations

T-bet Regulates the Terminal Maturation and Homeostasis of NK and Vα14i NKT Cells

2004 • 689 citations

In vivo developmental stages in murine natural killer cell maturation

2002 • 588 citations

Requirement for natural killer cell-produced interferon gamma in defense against murine cytomegalovirus infection and enhancement of this defense pathway by interleukin 12 administration.

1995 • 458 citations

Natural killer (NK) cells are present in mice with severe combined immunodeficiency (scid).

1985 • 362 citations

T-bet is required for optimal production of IFN-γ and antigen-specific T cell activation by dendritic cells

2003 • 250 citations

Interleukin (IL)-15Rα–deficient Natural Killer Cells Survive in Normal but Not IL-15Rα–deficient Mice

2003 • 241 citations

In Vivo Survival and Homeostatic Proliferation of Natural Killer Cells

2003 • 238 citations

Impaired Assembly yet Normal Trafficking of MHC Class I Molecules in Tapasin Mutant Mice

2000 • 207 citations

SingleH2Kb, H2Db and doubleH2KbDb knockout mice: peripheral CD8+ T cell repertoire and antilymphocytic choriomeningitis virus cytolytic responses

1999 • 198 citations

Commitment of Common T/Natural Killer (Nk) Progenitors to Unipotent T and Nk Progenitors in the Murine Fetal Thymus Revealed by a Single Progenitor Assay

1999 • 169 citations

Cutting Edge: Inhibitory Functions of the Killer Cell Lectin-Like Receptor G1 Molecule During the Activation of Mouse NK Cells

2002 • 144 citations

Requirement for membrane lymphotoxin in natural killer cell development

1999 • 137 citations

Clonal Acquisition of Inhibitory Ly49 Receptors on Developing NK Cells Is Successively Restricted and Regulated by Stromal Class I MHC

2000 • 128 citations

Differentiation of NK1.1+, Ly49+ NK cells from flt3+ multipotent marrow progenitor cells.

1999 • 124 citations

Major histocompatibility complex (MHC) class I K^bD^b−/− deficient mice possess functional CD8+ T cells and natural killer cells

1998 • 120 citations

Expansion and Contraction of the NK Cell Compartment in Response to Murine Cytomegalovirus Infection

2004 • 108 citations

Differentiation of NK1.1+, Ly49+ NK Cells from flt3+ Multipotent Marrow Progenitor Cells

1999 • 106 citations

NK cell expression of the killer cell lectin-like receptor G1 (KLRG1), the mouse homolog of MAFA, is modulated by MHC class I molecules

2000 • 100 citations

Murine natural killer cells do not express functional transcripts of the alpha-, beta-, or gamma-chain genes of the T cell receptor.

1986 • 72 citations

Signal Via Lymphotoxin-βR on Bone Marrow Stromal Cells Is Required for an Early Checkpoint of NK Cell Development

2001 • 66 citations

T cell receptor genes do not rearrange or express functional transcripts in natural killer cells of scid mice.

1987 • 59 citations

Murine natural killer cells stimulated in vivo do not express the T cell receptor alpha, beta, gamma, T3 delta, or T3 epsilon genes.

1987 • 58 citations

Gamma interferon and 5-azacytidine cause transcriptional elevation of class I major histocompatibility complex gene expression in K562 leukemia cells in the absence of differentiation.

1986 • 48 citations

Natural Killer Cells and Their Precursors in Mice With Severe Combined Immunodeficiency

1989 • 24 citations