Direct evidence of oxidative damage in acute and chronic phases of experimental colitis in rats

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1990 • 3,220 citations

Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury

1990 • 2,639 citations

Hapten-Induced Model of Chronic Inflammation and Ulceration in the Rat Colon

1989 • 1,681 citations

Hapten-induced model of chronic inflammation and ulceration in the rat colon

1989 • 706 citations

Oxidants and free radicals in inflammatory bowel disease

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Analysis of biological thiols: Derivatization with monobromobimane and separation by reverse-phase high-performance liquid chromatography

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Role of oxygen-derived free radicals in digestive tract diseases.

1983 • 362 citations

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1992 • 342 citations

Physiology of oxygen radicals

1986 • 330 citations

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1992 • 260 citations

Clinical Evidence Supporting the Radical Scavenger Mechanism of 5-Aminosalicylic Acid

1990 • 230 citations

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1990 • 201 citations

Metallothionein

1987 • 177 citations

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Nutritional and Metabolic Aspects of Glutathione

1989 • 164 citations

Metabolism of trinitrobenzene sulfonic acid by the rat colon produces reactive oxygen species

1991 • 128 citations

Decrease in two intestinal copper/zinc containing proteins with antioxidant function in inflammatory bowel disease.

1991 • 123 citations

Oxidant defense mechanisms in the human colon

1990 • 122 citations

Role of reactive oxygen species in intestinal diseases

1992 • 109 citations

Diminished neutrophil function in Crohn's disease and ulcerative colitis identified by decreased oxidative metabolism and low superoxide dismutase content.

1988 • 101 citations

Increased production of luminol enhanced chemiluminescence by the inflamed colonic mucosa in patients with ulcerative colitis.

1993 • 95 citations

Glutathione prevents ethanol induced gastric mucosal damage and depletion of sulfhydryl compounds in humans.

1993 • 93 citations

Role of oxygen-derived free radical scavengers in the management of recurrent attacks of ulcerative colitis: a new approach.

1992 • 82 citations

Cytoprotection against neutrophil derived hypochlorous acid: a potential mechanism for the therapeutic action of 5-aminosalicylic acid in ulcerative colitis.

1990 • 81 citations

Generation of radical anions of nitrofurantoin, misonidazole, and metronidazole by ascorbate

1987 • 50 citations

Rat enterocyte injury by oxygen-dependent processes

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Protective influence of oxypurinol on the trinitrobenzene sulfonic acid(TNB) model of inflammatory bowel disease in rats.

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1992 • 19 citations

The Healing Process of Chronic Colitis in Rats, Induced by 2,4,6-Trinitrobenzene Sulfonic Acid, with Special Reference to the Role of Fibronectin

1994 • 8 citations