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Generation of radical anions of nitrofurantoin, misonidazole, and metronidazole by ascorbate

Data up to Jan 2025

Published1987
Citations50
References31

Total Citations Per Year

Abstract

References (31)

Oxidation of ascorbic acid with superoxide anion generated by the xanthine-xanthine oxidase system

1975 • 565 citations

REEVALUATION OF THE SPECTRAL AND KINETIC PROPERTIES OF HO2 AND O2 FREE RADICALS

1978 • 456 citations

The role of catalytic superoxide formation in the O2 inhibition of nitroreductase

1975 • 306 citations

Kinetics and mechanism for the oxidation of ascorbic acid/ascorbate by HO2/O2- (hydroperoxyl/superoxide) radicals. A pulse radiolysis and stopped-flow photolysis study

1983 • 231 citations

Mechanism of microsomal and mitochondrial nitroreductase. Electron spin resonance evidence for nitroaromatic free radical intermediates

1975 • 195 citations

Determination of Na+, K+, Mg2+, Cu2+, Zn2+, and Mn2+ in Rat Brain Regions

1973 • 193 citations

Oxygen inhibition of nitroreductase: Electron transfer from nitro radical-anions to oxygen

1976 • 184 citations

Vitamin C: Its molecular biology and medical potential

1976 • 170 citations

Some reactions and properties of nitro radical-anions important in biology and medicine.

1985 • 169 citations

Vitamin C: Its Molecular Biology and Medical Potential

1977 • 166 citations

Kinetics and mechanism for the oxidation of ascorbic acid/ascorbate by HO_2/O_2-radicals. A pulse radiolysis and stopped-flow photolysis study.

1983 • 150 citations

Chemical modifiers of cancer treatment.

1988 • 127 citations

Clinical testing of the radiosensitiser Ro-07-0582 I. dose tolerance, serum and tumour concentrations

1976 • 125 citations

Reduction of nifurtimox and nitrofurantoin to free radical metabolites by rat liver mitochondria. Evidence of an outer membrane-located nitroreductase.

1984 • 107 citations

Biochemistry of reduction of nitro heterocycles

1986 • 102 citations

CYTOTOXIC REACTIONS OF FREE RADICAL SPECIES OF OXYGEN*

1978 • 101 citations

The electron spin resonance spectrum of the tyrosyl radical

1985 • 95 citations

On the brain ascorbic acid and its importance in metabolism of biogenic amines

1977 • 83 citations

Electron-Affinic Sensitization: VI. A Pulse Radiolysis and ESR Comparison of Some 2- and 5-Nitroimidazoles

1975 • 83 citations

Ascorbate anion potentiates cytotoxicity of nitro-aromatic compounds under hypoxic and anoxic conditions

1979 • 68 citations

Sulphydryls, ascorbate and oxygen as modifiers of the toxicity and metabolism of misonidazole in vitro

1980 • 49 citations

o ‐ und p ‐Nitro‐phenylhydroxylamin

1936 • 49 citations

Ascorbate-enhanced Cytotoxicity of misonidazole

1978 • 47 citations

THE OXIDATION OF ASCORBATE BY ELECTRON AFFINIC DRUGS AND CARCINOGENS

1978 • 41 citations

In situ radiolysis electron spin resonance study of the radical-anions of substituted nitroimidazoles and nitroaromatic compounds

1978 • 37 citations

The catalytic effect of the carcinogen “4-nitroquinoline-N-oxide” on the oxidation of vitamin C

1976 • 31 citations

Correlation analysis of ESR spectra on a small computer

1986 • 26 citations

ESR spectra of electrochemically generated anion radicals of the nitrofuran series

1983 • 18 citations

Sensitivity of Trichomonas vaginalis to Metronidazole in Medium with Different Concentrations of Iron and Ascorbate

1982 • 4 citations

Reduction of the metallochromic indicators murexide and tetramethylmurexide to their free radical metabolites by cytoplasmic enzymes and reducing agents

1986 • 3 citations

Toxicity of Metronidazole and Sodium Ascorbate to Hypoxic SV40- Transformed 3T3 Cells

1979 • 2 citations

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Generation of radical anions of nitrofurantoin, misonidazole, and metronidazole by… (1987) – Archives of Biochemistry and Biophysics | Metascience Observatory Explorer