Decrease in two intestinal copper/zinc containing proteins with antioxidant function in inflammatory bowel disease.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Superoxide Dismutase

1969 • 12,578 citations

The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent. Application to the radioimmunoassay

1973 • 3,279 citations

Possible role for metallothionein in protection against radiation-induced oxidative stress. Kinetics and mechanism of its reaction with superoxide and hydroxyl radicals

1985 • 1,042 citations

Ischemic injury in the cat small intestine: Role of superoxide radicals

1982 • 771 citations

Xanthine oxidase and neutrophil infiltration in intestinal ischemia

1986 • 722 citations

PATHOGENESIS OF CROHN'S DISEASE: MULTIFOCAL GASTROINTESTINAL INFARCTION

1989 • 589 citations

Neutrophil-mediated mucosal injury

1988 • 445 citations

Tissue‐specific regulation of zinc metabolism and metallothionein genes by interleukin 1

1988 • 314 citations

Inhibition of hydroxyl-radical-generated DNA degradation by metallothionein

1989 • 218 citations

Role of reactive oxygen metabolites in experimental colitis.

1990 • 201 citations

Metallothionein

1987 • 177 citations

Involvement of Metallothionein in the Hepatic Metabolism of Copper

1987 • 161 citations

The scavenging of oxidants by sulphasalazine and its metabolites

1987 • 155 citations

Oxygen radicals: mediators of gastrointestinal pathophysiology.

1989 • 146 citations

Effect of sulphasalazine and its metabolites on the generation of reactive oxygen species.

1987 • 135 citations

Active oxygen species generated by monocytes and polymorphonuclear cells in Crohn's disease

1988 • 126 citations

Respiratory burst activity of intestinal macrophages in normal and inflammatory bowel disease.

1989 • 125 citations

Radioresistance in cells with high content of metallothionein

1982 • 112 citations

Diminished neutrophil function in Crohn's disease and ulcerative colitis identified by decreased oxidative metabolism and low superoxide dismutase content.

1988 • 101 citations

Effect of Liposomal-Encapsulated Superoxide Dismutase on Active Oxygen-Related Human Disorders. A Preliminary Study

1985 • 96 citations

Phase II trial of copper zinc superoxide dismutase (CuZnSOD) in treatment of Crohn's disease

1989 • 82 citations

5-Aminosalicylate: Oxidation by activated leukocytes and protection of cultured cells from oxidative damage

1987 • 75 citations

Physiological role of glucocorticoids on rat serum and liver metallothionein in basal and stress conditions

1988 • 62 citations

Zinc Deficiency in Inflammatory Bowel Disease

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Leukocytic endogenous mediator in Crohn's disease

1978 • 50 citations

Value of Indium-111 Granulocyte Scintigraphy in the Assessment of Crohn’s Disease of the Small Intestine: Prospective Investigation

1988 • 37 citations

Reaction of bovine‐liver copper‐zinc superoxide dismutase with hydrogen peroxide

1989 • 36 citations

Alteration of Radiosensitivity in Metallothionein Induced Mice and a Possible Role of Zn-Cu-Thionein in GSH-Peroxidase System

1987 • 30 citations

Sulfasalazine and its metabolites attenuate respiratory burst of leukocytes--a possible mechanism of anti-inflammatory effects.

1987 • 25 citations

Development of a radioimmunoassay for human metallothionein

1990 • 13 citations

Isolation, characterization, and determination of human liver (copper/zinc) metallothionein

1990 • 10 citations

THE IMMUNOCYTOCHEMICAL DEMONSTRATION OF METALLOTHIONEIN IN HUMAN LIVER AND SMALL INTESTINE

1986 • 5 citations