CCR5 mediates specific migration of Toxoplasma gondii—primed CD8+ lymphocytes to inflammatory intestinal epithelial cells

Differential Expression of Chemokine Receptors and Chemotactic Responsiveness of Type 1 T Helper Cells (Th1s) and Th2s

1998 • 2,048 citations

Direct and sensitive detection of a pathogenic protozoan, Toxoplasma gondii, by polymerase chain reaction

1989 • 895 citations

Chemokines: immunology's high impact factors

2001 • 845 citations

Lymphocyte Cc Chemokine Receptor 9 and Epithelial Thymus-Expressed Chemokine (Teck) Expression Distinguish the Small Intestinal Immune Compartment

2000 • 620 citations

Human G Protein–Coupled Receptor Gpr-9-6/Cc Chemokine Receptor 9 Is Selectively Expressed on Intestinal Homing T Lymphocytes, Mucosal Lymphocytes, and Thymocytes and Is Required for Thymus-Expressed Chemokine–Mediated Chemotaxis

1999 • 492 citations

Impaired Host Defense, Hematopoiesis, Granulomatous Inflammation and Type 1–Type 2 Cytokine Balance in Mice Lacking CC Chemokine Receptor 1

1997 • 454 citations

Toll-like Receptor 4 Resides in the Golgi Apparatus and Colocalizes with Internalized Lipopolysaccharide in Intestinal Epithelial Cells

2002 • 414 citations

Contrasting Effects of CCR5 and CCR2 Deficiency in the Pulmonary Inflammatory Response to Influenza A Virus

2000 • 388 citations

CCR5 provides a signal for microbial induced production of IL-12 by CD8α+ dendritic cells

2000 • 340 citations

A Role for CCR9 in T Lymphocyte Development and Migration

2002 • 321 citations

Mice lacking the CCR9 CC-chemokine receptor show a mild impairment of early T- and B-cell development and a reduction in T-cell receptor γδ+ gut intraepithelial lymphocytes

2001 • 291 citations

IP-10 Is Critical for Effector T Cell Trafficking and Host Survival in Toxoplasma gondii Infection

2000 • 283 citations

Perforin-Dependent Brain-Infiltrating Cytotoxic CD8+ T Lymphocytes Mediate Experimental Cerebral Malaria Pathogenesis

2003 • 283 citations

Mice with a Selective Deletion of the CC Chemokine Receptors 5 or 2 Are Protected from Dextran Sodium Sulfate-Mediated Colitis: Lack of CC Chemokine Receptor 5 Expression Results in a NK1.1+ Lymphocyte-Associated Th2-Type Immune Response in the Intestine

2000 • 253 citations

Chemokine Expression Precedes Inflammatory Cell Infiltration and Chemokine Receptor and Cytokine Expression during the Initiation of Murine Lupus Nephritis

2001 • 234 citations

A dichotomous role for nitric oxide during acuteToxoplasma gondiiinfection in mice

1997 • 226 citations

CXCR2 Deficiency Confers Impaired Neutrophil Recruitment and Increased Susceptibility DuringToxoplasma gondiiInfection

2001 • 196 citations

Cutting Edge: Role of C-C Chemokine Receptor 5 in Organ-Specific and Innate Immunity toCryptococcus neoformans

1999 • 168 citations

Human intestinal lamina propria and intraepithelial lymphocytes express receptors specific for chemokines induced by inflammation

2000 • 155 citations

Oral Infection of C57BL/6 Mice withToxoplasma gondii:A New Model of Inflammatory Bowel Disease?

2002 • 146 citations

`In the Belly of the Beast'

1999 • 145 citations

Transimmortalized mouse intestinal cells (m-ICc12) that maintain a crypt phenotype

1996 • 137 citations

MIP-2 secreted by epithelial cells increases neutrophil and lymphocyte recruitment in the mouse intestine

2001 • 136 citations

Tissue and Cell Distribution of the Multidrug Resistance-Associated Protein (MRP) in Mouse Intestine and Kidney

1999 • 136 citations

Toxoplasma gondii oral infection induces specific cytotoxic CD8 alpha/beta+ Thy-1+ gut intraepithelial lymphocytes, lytic for parasite-infected enterocytes.

1994 • 123 citations

Lamina Propria CD4+ T Lymphocytes Synergize with Murine Intestinal Epithelial Cells to Enhance Proinflammatory Response Against an Intracellular Pathogen

2002 • 113 citations

Characterization of chemokines and chemokine receptors in two murine models of inflammatory bowel disease: IL-10/ mice and Rag-2/ mice reconstituted with CD4+CD45RBhigh T cells

2001 • 104 citations

Murine ileitis after intracellular parasite infection is controlled by TGF-β–producing intraepithelial lymphocytes

2001 • 94 citations

Adoptive transfer of gut intraepithelial lymphocytes protects against murine infection with Toxoplasma gondii.

1997 • 85 citations

Experimental murine colitis is regulated by two genetic loci, including one on chromosome 11 that regulates IL-12 responses

2002 • 76 citations

In the belly of the beast: subversion of macrophage proinflammatory signalling cascades during Toxoplasma gondii infection

2003 • 72 citations

RANTES stimulates inflammatory cascades and receptor modulation in murine astrocytes

2002 • 61 citations

Intraepithelial Lymphocytes Traffic to the Intestine and Enhance Resistance toToxoplasma gondiiOral Infection

1999 • 58 citations

Functional Expression of Chemokine Receptor CCR5 on CD4⁺T Cells during Virus-Induced Central Nervous System Disease

2002 • 58 citations

A pivotal role for CC chemokine receptor 5 in T-cell migration to tumor sites induced by interleukin 12 treatment in tumor-bearing mice.

2002 • 46 citations

Measurement of the efficacy of vaccines and antimicrobial therapy against infection with Toxoplasma gondii

2000 • 30 citations