Cell-free activation of a DNA-binding protein by epidermal growth factor

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Signal transduction by receptors with tyrosine kinase activity

1990 • 5,528 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

Oncogenes and signal transduction

1991 • 2,816 citations

G ₁ Events and Regulation of Cell Proliferation

1989 • 2,203 citations

SH2 and SH3 Domains: Elements that Control Interactions of Cytoplasmic Signaling Proteins

1991 • 1,931 citations

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

1992 • 1,636 citations

Early Signals in the Mitogenic Response

1986 • 1,498 citations

PRIMARY RESPONSE GENES INDUCED BY GROWTH FACTORS AND TUMOR PROMOTERS

1991 • 1,078 citations

Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method.

1988 • 983 citations

Interferon-Dependent Tyrosine Phosphorylation of a Latent Cytoplasmic Transcription Factor

1992 • 906 citations

A protein tyrosine kinase in the interferon αβ signaling pathway

1992 • 876 citations

Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

1992 • 692 citations

Nerve growth factor receptors on human melanoma cells in culture.

1977 • 670 citations

Signal Transduction by the Platelet-Derived Growth Factor Receptor

1989 • 653 citations

The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter.

1990 • 615 citations

Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins

1989 • 524 citations

A small-scale procedure for preparation of nuclear extracts that support efficient transcription and pre-mRNA splicing

1988 • 485 citations

A transcription factor with SH2 and SH3 domains is directly activated by an interferon α-induced cytoplasmic protein tyrosine kinase(s)

1992 • 378 citations

Occupation of the c-fos serum response element in vivo by a multi-protein complex is unaltered by growth factor induction

1989 • 346 citations

Signal transduction of the human granulocyte-macrophage colony- stimulating factor and interleukin-3 receptors involves tyrosine phosphorylation of a common set of cytoplasmic proteins

1990 • 294 citations

The SRE: a growth factor responsive transcriptional regulator.

1990 • 287 citations

The c-fos serum response element responds to protein kinase C-dependent and -independent signals but not to cyclic AMP.

1988 • 245 citations

Identification of c-fos sequences involved in induction by insulin and phorbol esters.

1988 • 184 citations

Inducible binding of a factor to the c-fos regulatory region.

1987 • 168 citations

High-level expression of human insulin receptor cDNA in mouse NIH 3T3 cells.

1987 • 151 citations

Two distinct cellular phosphoproteins bind to the c-fos serum response element.

1989 • 140 citations

Insulin and growth factor effects on c-fos expression in normal and protein kinase C-deficient 3T3-L1 fibroblasts and adipocytes.

1986 • 137 citations

Activation of Transcription Factors by Interferon-Alpha in a Cell-Free System

1992 • 89 citations

Proteins with SH2 domains: transducers in the tyrosine kinase signaling pathway.

1992 • 82 citations