Regulated tyrosine phosphorylation at the tips of growth cone filopodia.

Focal Adhesions: Transmembrane Junctions Between the Extracellular Matrix and the Cytoskeleton

1988 • 2,137 citations

ACTIN AND ACTIN-BINDING PROTEINS. A CRITICAL EVALUATION OF MECHANISMS AND FUNCTIONS

1986 • 1,493 citations

trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3

1991 • 1,078 citations

Actions of cytochalasins on the organization of actin filaments and microtubules in a neuronal growth cone.

1988 • 851 citations

trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor

1991 • 830 citations

Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors

1991 • 520 citations

Rous sarcoma virus-transformed fibroblasts adhere primarily at discrete protrusions of the ventral membrane called podosomes

1985 • 426 citations

[30] Use and specificity of genistein as inhibitor of protein-tyrosine kinases

1991 • 421 citations

Disoriented pathfinding by pioneer neurone growth cones deprived of filopodia by cytochalasin treatment

1986 • 378 citations

Growth cone morphology and trajectory in the lumbosacral region of the chick embryo

1985 • 344 citations

Genetic analysis of a drosophila neural cell adhesion molecule: Interaction of fasciclin I and abelson tyrosine kinase mutations

1990 • 340 citations

Specific proto-oncogenic tyrosine kinases of src family are enriched in cell-to-cell adherens junctions where the level of tyrosine phosphorylation is elevated.

1991 • 310 citations

Nerve growth cone lamellipodia contain two populations of actin filaments that differ in organization and polarity.

1992 • 305 citations

Growth cone morphology varies with position in the developing mouse visual pathway from retina to first targets

1987 • 302 citations

Oligodendrocytes arrest neurite growth by contact inhibition

1990 • 285 citations

Collapse of growth cone structure on contact with specific neurites in culture

1987 • 284 citations

Nerve growth factor rapidly stimulates tyrosine phosphorylation of phospholipase C-gamma 1 by a kinase activity associated with the product of the trk protooncogene.

1991 • 272 citations

Pioneer growth cone steering decisions mediated by single filopodial contacts in situ

1990 • 268 citations

The trk proto-oncogene rescues NGF responsiveness in mutant NGF-nonresponsive PC12 cell lines

1991 • 252 citations

Stages in axon formation: observations of growth of Aplysia axons in culture using video-enhanced contrast-differential interference contrast microscopy.

1986 • 235 citations

Pioneer axons lose directed growth after selective killing of guidepost cells

1983 • 229 citations

A sensory role for neuronal growth cone filopodia

1993 • 223 citations

Phosphotyrosine-containing proteins are concentrated in focal adhesions and intercellular junctions in normal cells.

1985 • 218 citations

Differences in the organization of actin in the growth cones compared with the neurites of cultured neurons from chick embryos.

1983 • 214 citations

Three receptor-linked protein-tyrosine phosphatases are selectively expressed on central nervous system axons in the Drosophila embryo

1991 • 212 citations

Analysis of microspike movements on the neuronal growth cone

1985 • 205 citations

Neural cell adhesion molecules modulate tyrosine phosphorylation of tubulin in nerve growth cone membranes

1992 • 197 citations

c-src gene product in developing rat brain is enriched in nerve growth cone membranes.

1988 • 193 citations

Nerve growth factor induces protein-tyrosine phosphorylation.

1988 • 184 citations

Cyclic AMP induces changes in distribution and transport of organelles within growth cones of Aplysia bag cell neurons

1987 • 177 citations

Pioneer growth cone steering along a series of neuronal and non- neuronal cues of different affinities

1986 • 168 citations

Growth cone behavior and production of traction force.

1990 • 166 citations

On the importance of being inhibited, or saying no to growth cones

1988 • 158 citations

Actin dynamics in growth cones

1991 • 145 citations

Specific inhibition of cytoplasmic protein tyrosine kinases by herbimycin A in vitro

1991 • 139 citations

Tubulin is phosphorylated at tyrosine by pp60c-src in nerve growth cone membranes.

1990 • 137 citations

Tyrosine Phosphorylation of Actin in Dictyostelium Associated with Cell-Shape Changes

1993 • 118 citations

Accumulation of talin in nodes at the edge of the lamellipodium and separate incorporation into adhesion plaques at focal contacts in fibroblasts.

1991 • 116 citations

Neurite extension across regions of low cell-substratum adhesivity: Implications for the guidepost hypothesis of axonal pathfinding

1986 • 114 citations

Rapid effects of laminin on the growth cone

1992 • 104 citations

Concentration of membrane antigens by forward transport and trapping in neuronal growth cones

1990 • 94 citations

A precursor of the focal contact in cultured fibroblasts

1988 • 90 citations

Neuronal growth cones: specific interactions mediated by filopodial insertion and induction of coated vesicles.

1984 • 88 citations

Phosphotyrosine-modified proteins are concentrated at the membranes of epithelial and endothelial cells during tissue development in chick embryos.

1988 • 84 citations

Inhibition of tyrosine phosphorylation potentiates substrate‐induced neurite growth

1992 • 81 citations

p59fyn in rat brain is localized in developing axonal tracts and subpopulations of adult neurons and glia.

1993 • 74 citations

Cytoskeletal targets for oncogenic tyrosine kinases

1991 • 73 citations

Looking into growth cones

1989 • 64 citations

Nerve growth factor stimulates the tyrosine phosphorylation of MAP2 kinase in PC12 cells

1991 • 56 citations

Increased Neurite Outgrowth Induced by Inhibition of Protein Tyrosine Kinase Activity in PC12 Pheochromocytoma Cells

1993 • 55 citations

Cloning and characterization of a receptor-class phosphotyrosine phosphatase gene expressed on central nervous system axons in Drosophila melanogaster.

1991 • 46 citations

Substrate‐bound factors stimulate engorgement of growth cone lamellipodia during neurite elongation

1991 • 40 citations

Differentiation of neuronal growth cones: specialization of filopodial tips for adhesive interactions.

1985 • 34 citations