Lack of vesicular zinc in mossy fibers does not affect synaptic excitability of CA3 pyramidal cells in zinc transporter 3 knockout mice

Interneurons of the hippocampus

1998 • 3,399 citations

Release of endogenous Zn2+ from brain tissue during activity

1984 • 1,125 citations

Neurobiology of Zinc and Zinc-Containing Neurons

1989 • 1,075 citations

Micromolar concentrations of Zn2+ antagonize NMDA and GABA responses of hippocampal neurons

1987 • 852 citations

Stimulation-induced uptake and release of zinc in hippocampal slices

1984 • 812 citations

GABAergic Cells Are the Major Postsynaptic Targets of Mossy Fibers in the Rat Hippocampus

1998 • 738 citations

ZnT-3, a putative transporter of zinc into synaptic vesicles

1996 • 712 citations

Zinc Selectively Blocks the Action of N -Methyl-D-Aspartate on Cortical Neurons

1987 • 678 citations

Elimination of zinc from synaptic vesicles in the intact mouse brain by disruption of the ZnT 3 gene

1999 • 534 citations

Organization of the entorhinal—hippocampal system: A review of current anatomical data

1993 • 524 citations

The Actions of Synaptically Released Zinc at Hippocampal Mossy Fiber Synapses

2000 • 477 citations

Modulation of inhibitory and excitatory amino acid receptor ion channels by zinc

1994 • 445 citations

Zinc-Induced Collapse of Augmented Inhibition by GABA in a Temporal Lobe Epilepsy Model

1996 • 419 citations

Three‐dimensional analysis of the structure and composition of CA3 branched dendritic spines and their synaptic relationships with mossy fiber boutons in the rat hippocampus

1992 • 418 citations

Rapid Seizure-Induced Reduction of Benzodiazepine and Zn²⁺Sensitivity of Hippocampal Dentate Granule Cell GABA_AReceptors

1997 • 418 citations

Mechanisms of neocortical epileptogenesis in vitro

1982 • 409 citations

A physiological role for endogenous zinc in rat hippocampal synaptic neurotransmission

1991 • 378 citations

Special axo‐dendritic synapses in the hippocampal cortex: Electron and light microscopic studies on the layer of mossy fibers

1961 • 375 citations

Functional and molecular distinction between recombinant rat GABAA receptor subtypes by Zn2+

1990 • 370 citations

Epileptiform activity in combined slices of the hippocampus, subiculum and entorhinal cortex during perfusion with low magnesium medium

1986 • 354 citations

Ultrastructural localization of zinc transporter-3 (ZnT-3) to synaptic vesicle membranes within mossy fiber boutons in the hippocampus of mouse and monkey

1997 • 352 citations

Frequency‐dependent depression of inhibition in guinea‐pig neocortex in vitro by GABAB receptor feed‐back on GABA release.

1989 • 348 citations

Synchronized burst discharge in disinhibited hippocampal slice. I. Initiation in CA2-CA3 region

1983 • 342 citations

Changes in excitatory and inhibitory synaptic potentials leading to epileptogenic activity

1980 • 321 citations

Zn2+: an endogenous modulator of ligand- and voltage-gated ion channels

1994 • 284 citations

Synchronous GABA-mediated potentials and epileptiform discharges in the rat limbic system in vitro.

1996 • 275 citations

Modulation of excitatory amino acid receptors by group IIB metal cations in cultured mouse hippocampal neurones.

1989 • 275 citations

Epileptiform burst activity induced by potassium in the hippocampus and its regulation by GABA-mediated inhibition

1987 • 272 citations

Rapid Translocation of Zn²⁺From Presynaptic Terminals Into Postsynaptic Hippocampal Neurons After Physiological Stimulation

2001 • 260 citations

Differential Epilepsy-Associated Alterations in Postsynaptic GABA_A Receptor Function in Dentate Granule and CA1 Neurons

1997 • 250 citations

Synchronous GABA-Mediated Potentials and Epileptiform Discharges in the Rat Limbic SystemIn Vitro

1996 • 249 citations

Seizures and neuronal damage in mice lacking vesicular zinc

2000 • 235 citations

Electrophysiological mechanisms of kainic acid-induced epileptiform activity in the rat hippocampal slice

1984 • 199 citations

Activity-dependent disinhibition. III. Desensitization and GABAB receptor-mediated presynaptic inhibition in the hippocampus in vitro

1989 • 177 citations

Slow Kinetics of Miniature IPSCs during Early Postnatal Development in Granule Cells of the Dentate Gyrus

1997 • 172 citations

Imaging free zinc in synaptic terminals in live hippocampal slices

1997 • 167 citations

The slow inhibitory postsynaptic potential in rat hippocampal CA1 neurones is blocked by intracellular injection of QX-314

1990 • 164 citations

Neurons of origin of zinc-containing pathways and the distribution of zinc-containing boutons in the hippocampal region of the rat

1992 • 163 citations

Cellular and synaptic basis of kainic acid-induced hippocampal epileptiform activity

1983 • 157 citations

Spontaneous and evoked release of endogenous Zn2+ in the hippocampal mossy fiber zone of the rat in situ

1985 • 154 citations

Removing zinc from synaptic vesicles does not impair spatial learning, memory, or sensorimotor functions in the mouse

2001 • 138 citations

Differential effect of zinc on the vertebrate GABA_A‐receptor complex

1990 • 112 citations

Kinetic and mutational analysis of Zn²⁺ modulation of recombinant human inhibitory glycine receptors

2000 • 108 citations

Noncompetitive inhibition of gamma-aminobutyric acidA channels by Zn.

1991 • 104 citations

Blockade of excitatory synaptic transmission by 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) in the hippocampus in vitro

1988 • 83 citations

The role of excitatory amino acid receptors in the propagation of epileptiform discharges from the entorhinal cortex to the dentate gyrus in vitro

1990 • 80 citations

Postnatal development of hippocampal dentate granule cell gamma-aminobutyric acidA receptor pharmacological properties.

1999 • 67 citations

Developmental change of GABAA receptor-mediated current in rat hippocampus

2000 • 52 citations

Zn²⁺ inhibition of recombinant GABA_A receptors: an allosteric, state‐dependent mechanism determined by the γ‐subunit

1998 • 50 citations

Persistent function of mossy fibre synapses after metal chelation with DEDTC (Antabuse)

1975 • 48 citations

Properties of GABA‐mediated synaptic potentials induced by zinc in adult rat hippocampal pyramidal neurones.

1993 • 46 citations

Responses of pyriform cortex neurons to excitatory amino acids: Voltage dependence, conductance changes, and effects of divalent cations

1987 • 44 citations

Inhibition of ATP‐activated current by zinc in dorsal root ganglion neurones of bullfrog

1997 • 42 citations

Zinc enhances GABAergic transmission in rat neocortical neurons

1993 • 22 citations

Induction of giant depolarizing potentials by zinc in area CA1 of the rat hippocampus does not result from block of GABAB receptors

1992 • 21 citations

Regionally Selective Blockade of GABAergic Inhibition by Zinc in the Thalamocortical System: Functional Significance

2000 • 17 citations

Giant GABA_B‐mediated Synaptic Potentials Induced by Zinc in the Rat Hippocampus: Paradoxical Effects of Zinc on the GABA_B Receptor

1993 • 15 citations

Differential effects of zinc on hyperpolarizing and depolarizing GABAA synaptic potentials in hippocampal slice cultures

1995 • 6 citations