Rapid Seizure-Induced Reduction of Benzodiazepine and Zn²⁺Sensitivity of Hippocampal Dentate Granule Cell GABA_AReceptors

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Down-Regulation of Na⁺/K⁺ATPase Activity by Human Parvovirus B19 Capsid Protein VP1

2013 • 8,607 citations

Modification of seizure activity by electrical stimulation: II. Motor seizure

1972 • 6,939 citations

Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein

2014 • 5,592 citations

Proposal for Revised Clinical and Electroencephalographic Classification of Epileptic Seizures

1981 • 3,249 citations

GABA_A Receptor Channels

1994 • 1,948 citations

Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology

1989 • 1,283 citations

A prospective, population-based epidemiologic study of status epilepticus in Richmond, Virginia

1996 • 1,041 citations

Permanently altered hippocampal structure, excitability, and inhibition after experimental status epilepticus in the rat: The “dormant basket cell” hypothesis and its possible relevance to temporal lobe epilepsy

1991 • 706 citations

Antiepileptic Drug Mechanisms of Action

1995 • 575 citations

From ion currents to genomic analysis: Recent advances in GABA_A receptor research

1995 • 473 citations

Neuronal loss induced in limbic pathways by kindling: evidence for induction of hippocampal sclerosis by repeated brief seizures

1994 • 461 citations

Systemic Factors and Epileptic Brain Damage

1973 • 440 citations

Zinc-Induced Collapse of Augmented Inhibition by GABA in a Temporal Lobe Epilepsy Model

1996 • 419 citations

Isolation of neurons suitable for patch-clamping from adult mammalian central nervous systems

1986 • 416 citations

The functional anatomy and pathology of lithium-pilocarpine and high-dose pilocarpine seizures

1987 • 379 citations

Functional and molecular distinction between recombinant rat GABAA receptor subtypes by Zn2+

1990 • 370 citations

Systemic Cholinergic Agents Induce Seizures and Brain Damage in Lithium-Treated Rats

1983 • 364 citations

Functional anatomy of hippocampal seizures

1991 • 360 citations

Physiology of Status Epilepticus in Primates

1973 • 329 citations

Self-sustaining limbic status epilepticus induced by ‘continuous’ hippocampal stimulation: electrographic and behavioral characteristics

1989 • 293 citations

Properties of putative cerebellar gamma-aminobutyric acid A receptor isoforms.

1996 • 285 citations

Lasting potentiation of inhibition is associated with an increased number of gamma-aminobutyric acid type A receptors activated during miniature inhibitory postsynaptic currents.

1994 • 263 citations

Differential Epilepsy-Associated Alterations in Postsynaptic GABA_A Receptor Function in Dentate Granule and CA1 Neurons

1997 • 250 citations

Apoptosis and necrosis induced in different hippocampal neuron populations by repetitive perforant path stimulation in the rat

1996 • 227 citations

GABA_A receptors are differentially sensitive to zinc: dependence on subunit composition

1991 • 223 citations

Hippocampal Pyramidal Cell Loss in Human Status Epilepticus

1992 • 210 citations

Response of status epilepticus induced by lithium and pilocarpine to treatment with diazepam

1988 • 198 citations

gamma-Aminobutyric acid and benzodiazepine receptors in the kindling model of epilepsy: a quantitative radiohistochemical study

1985 • 164 citations

Repeated seizures induce long-term increase in hippocampal benzodiazepine receptors.

1980 • 150 citations

Prognostic factors of pentobarbital therapy for refractory generalized status epilepticus

1993 • 147 citations

Evidence that repetitive seizures in the hippocampus cause a lasting reduction of GABAergic inhibition

1989 • 143 citations

gamma‐Aminobutyric‐acid‐ and pentobarbitone‐gated chloride currents in internally perfused frog sensory neurones.

1985 • 141 citations

Null Mutation of c-fosImpairs Structural and Functional Plasticities in the Kindling Model of Epilepsy

1996 • 135 citations

Effects of drugs on the initiation and maintenance of status epilepticus induced by administration of pilocarpine to lithium-pretreated rats

1987 • 133 citations

Magnetic Resonance Imaging Evidence of Hippocampal Sclerosis in Progression: A Case Report

1994 • 123 citations

Changes in plasma catecholamines after tonic‐clonic seizures

1984 • 120 citations

Experimental status epilepticus alters γ‐aminobutyric acid type A receptor function in CA1 pyramidal neurons

1995 • 119 citations

Benzodiazepine receptor increases after repeated seizures: evidence for localization to dentate granule cells.

1982 • 113 citations

The competitive NMDA receptor antagonist CGP 40116 protects against status epilepticus-induced neuronal damage

1994 • 107 citations

Lasting potentiation of inhibition is associated with an increased number of GABA_A receptors activated during miniature inhibitory postsynaptic currents

1994 • 99 citations

Morphometric effects of intermittent kindled seizures and limbic status epilepticus in the dentate gyrus of the rat

1993 • 88 citations

Self‐sustaining limbic status epilepticus.

1991 • 77 citations

Treatment of Status Epilepticus

1993 • 73 citations

The Imaging of Individual Atoms

1996 • 72 citations

Ethanol, gamma-aminobutyrate type A receptors, and protein kinase C phosphorylation.

1995 • 71 citations

Loss of inhibition precedes delayed spontaneous seizures in the hippocampus after tetanic electrical stimulation

1989 • 71 citations

Protein kinase C enhances recombinant bovine α1β1γ2L GABAA receptor whole-cell currents expressed in L929 fibroblasts

1994 • 66 citations

Postnatal development of GABAA receptor function in somatosensory thalamus and cortex: whole-cell voltage-clamp recordings in acutely isolated rat neurons

1995 • 52 citations

Differential effects of petit mal anticonvulsants and convulsants on thalamic neurones: GABA current blockade

1990 • 49 citations

Whole-cell and single-channel α1 β1 γ2S GABAA receptor currents elicited by a “multipuffer” drug application device

1996 • 47 citations

The Effects of Raising Intracellular Calcium on Synaptic GABA A Receptor-channels

1996 • 46 citations

Inositol triphosphate, cyclic AMP, and cyclic GMP in rat brain regions after lithium and seizures

1992 • 44 citations

Loss of type II calcium/calmodulin-dependent kinase activity correlates with stages of development of electrographic seizures in status epilepticus in rat

1992 • 43 citations

The balance between excitation and inhibition in dentate granule cells and its role in epilepsy.

1992 • 41 citations

Intracellular Ca2+ suppressed a transient potassium current in hippocampal neurons

1991 • 41 citations

Status Epilepticus: Concepts in Diagnosis and Treatment

1990 • 38 citations

Loss of GABA _A receptors during partial status epilepticus

1994 • 36 citations

Regulation of GABAA receptor channels by anticonvulsant and convulsant drugs and by phosphorylation.

1992 • 22 citations

Messages of Support

1995 • 18 citations

Effects of non‐sedative anxiolytic drugs on responses to GABA and on diazepam‐induced enhancement of these responses on mouse neurones in cell culture

1988 • 10 citations