Zn²⁺ inhibition of recombinant GABA_A receptors: an allosteric, state‐dependent mechanism determined by the γ‐subunit

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Down-Regulation of Na⁺/K⁺ATPase Activity by Human Parvovirus B19 Capsid Protein VP1

2013 • 8,607 citations

Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein

2014 • 5,592 citations

Zinc coordination, function, and structure of zinc enzymes and other proteins

1990 • 1,731 citations

Sequence and functional expression of the GABAA receptor shows a ligand-gated receptor super-family

1987 • 1,621 citations

The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon

1992 • 1,525 citations

Release of endogenous Zn2+ from brain tissue during activity

1984 • 1,125 citations

Acetylcholine receptor channel imaged in the open state

1995 • 1,002 citations

Micromolar concentrations of Zn2+ antagonize NMDA and GABA responses of hippocampal neurons

1987 • 852 citations

Stimulation-induced uptake and release of zinc in hippocampal slices

1984 • 812 citations

The effect of subunit composition of rat brain GABAA receptors on channel function

1990 • 592 citations

Structural and functional basis for GABAA receptor heterogeneity

1988 • 590 citations

Functional properties of recombinant rat GABAA receptors depend upon subunit composition

1990 • 557 citations

Neurosteroids act on recombinant human GABAA receptors

1990 • 515 citations

CONDUCTANCE FLUCTUATIONS AND IONIC PORES IN MEMBRANES

1977 • 510 citations

Modulation of inhibitory and excitatory amino acid receptor ion channels by zinc

1994 • 445 citations

Intravesicular localization of zinc in rat telencephalic boutons. A histochemical study

1985 • 410 citations

Electron microscopical localization of the zinc in hippocampal mossy fibre synapses by a modified sulfide silver procedure

1967 • 393 citations

A physiological role for endogenous zinc in rat hippocampal synaptic neurotransmission

1991 • 378 citations

Functional and molecular distinction between recombinant rat GABAA receptor subtypes by Zn2+

1990 • 370 citations

Pharmacology of GABA receptor CI− channels in rat retinal bipolar cells

1993 • 353 citations

Assembly of GABAA receptor subunits: role of the delta subunit

1994 • 335 citations

How quickly can GABAA receptors open?

1994 • 249 citations

Dependence of the GABAA receptor gating kinetics on the alpha‐subunit isoform: implications for structure‐function relations and synaptic transmission.

1995 • 234 citations

Kinetic properties of the GABAA receptor main conductance state of mouse spinal cord neurones in culture.

1989 • 225 citations

Zinc-Containing Neurons

1994 • 224 citations

GABA_A receptors are differentially sensitive to zinc: dependence on subunit composition

1991 • 223 citations

Selective release of endogenous zinc from the hippocampal mossy fibers in situ

1987 • 220 citations

In situ hybridization histochemistry reveals a diversity of GABAA receptor subunit mRNAs in neurons of the rat spinal cord and dorsal root ganglia

1991 • 158 citations

The action of zinc on synaptic transmission and neuronal excitability in cultures of mouse hippocampus.

1989 • 151 citations

A novel modulatory binding site for zinc on the GABAA receptor complex in cultured rat neurones.

1992 • 132 citations

Differential effect of zinc on the vertebrate GABA_A‐receptor complex

1990 • 112 citations

Noncompetitive inhibition of gamma-aminobutyric acidA channels by Zn.

1991 • 104 citations

A single histidine residue is essential for zinc inhibition of GABA rho 1 receptors

1995 • 84 citations

Activation of a potassium current by rapid photochemically generated step increases of intracellular calcium in rat sympathetic neurons.

1987 • 82 citations

Negative modulation of the gamma-aminobutyric acid response by extracellular zinc.

1991 • 79 citations

Studies on the mechanism of action of picrotoxinin and other convulsants at the crustacean muscle GABA receptor

1986 • 74 citations

A novel effect of zinc on the lobster muscle GABA receptor

1982 • 72 citations

Antagonists of gaba responses, studied using internally perfused frog dorsal root ganglion neurons

1987 • 66 citations

α subunits influence Zn block of γ2 containing GABAA receptor currents

1995 • 66 citations

The “mixed” effect of picrotoxin on the GABA dose/conductance relation recorded from lobster muscle

1978 • 62 citations

Cationic modulation of rho 1-type gamma-aminobutyrate receptors expressed in Xenopus oocytes.

1994 • 58 citations

Multiple mechanisms of antagonism of?-aminobutyric acid (GABA) responses

1987 • 39 citations

Zinc is a mixed antagonist of homomeric rho 1 gamma-aminobutyric acid-activated channels.

1995 • 33 citations

Zinc enhances GABAergic transmission in rat neocortical neurons

1993 • 22 citations

Divalent cations reduce depolarization of primary afferent terminations by GABA

1987 • 11 citations