Evidence for the Role of Megalin in Renal Uptake of Transthyretin

A PECULIAR FORM OF PERIPHERAL NEUROPATHY

1952 • 1,049 citations

An Endocytic Pathway Essential for Renal Uptake and Activation of the Steroid 25-(OH) Vitamin D3

1999 • 989 citations

A common molecular basis for three inherited kidney stone diseases

1996 • 710 citations

Vitamin A in Health and Disease

1994 • 602 citations

39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor.

1991 • 586 citations

Defective forebrain development in mice lacking gp330/megalin.

1996 • 485 citations

Megalin Knockout Mice as an Animal Model of Low Molecular Weight Proteinuria

1999 • 432 citations

Potential mechanisms of thyroid disruption in humans: interaction of organochlorine compounds with thyroid receptor, transthyretin, and thyroid-binding globulin.

1999 • 397 citations

THE MAMMALIAN LOW-DENSITY LIPOPROTEIN RECEPTOR FAMILY

1999 • 362 citations

Organ distribution in rats of two members of the low-density lipoprotein receptor gene family, gp330 and LRP/alpha 2MR, and the receptor-associated protein (RAP).

1994 • 323 citations

Disruption of the transthyretin gene results in mice with depressed levels of plasma retinol and thyroid hormone.

1993 • 322 citations

Cubilin is an albumin binding protein important for renal tubular albumin reabsorption

2000 • 312 citations

Dent's disease; a familial proximal renal tubular syndrome with low-molecular-weight proteinuria, hypercalciuria, nephrocalcinosis, metabolic bone disease, progressive renal failure and a marked male predominance

1994 • 294 citations

Intra-renal and subcellular distribution of the human chloride channel, CLC-5, reveals a pathophysiological basis for Dent's disease

1999 • 281 citations

The Intrinsic Factor-Vitamin B12 Receptor and Target of Teratogenic Antibodies Is a Megalin-binding Peripheral Membrane Protein with Homology to Developmental Proteins

1998 • 254 citations

Evidence for an Essential Role of Megalin in Transepithelial Transport of Retinol

1999 • 238 citations

Transthyretin mutations in health and disease

1995 • 217 citations

Megalin-mediated endocytosis of transcobalamin-vitamin-B12 complexes suggests a role of the receptor in vitamin-B12 homeostasis.

1996 • 211 citations

Studies on the Protein-Protein and Protein-Ligand Interactions Involved in Retinol Transport in Plasma

1970 • 169 citations

Epithelial glycoprotein-330 mediates endocytosis of plasminogen activator-plasminogen activator inhibitor type-1 complexes

1993 • 169 citations

Membrane Receptors for Endocytosis in the Renal Proximal Tubule

1998 • 169 citations

Segmental distribution of the endocytosis receptor gp330 in renal proximal tubules.

1995 • 149 citations

Renal tubule gp330 is a calcium binding receptor for endocytic uptake of protein.

1992 • 147 citations

An X-ray study of the subunit structure of prealbumin

1971 • 126 citations

Biochemical marker in familial amyloidotic polyneuropathy, Portuguese type. Family studies on the transthyretin (prealbumin)-methionine-30 variant.

1985 • 116 citations

Receptor-Associated Protein Is Important for Normal Processing of Megalin in Kidney Proximal Tubules

2000 • 103 citations

beta2-glycoprotein-I (apolipoprotein H) and beta2-glycoprotein-I-phospholipid complex harbor a recognition site for the endocytic receptor megalin.

1998 • 94 citations

Thyroxine binding to transthyretin Met 119

1997 • 90 citations

Receptor-mediated uptake and internalization of transthyretin.

1990 • 84 citations

Plasma transthyretin. Tissue sites of degradation and turnover in the rat.

1988 • 82 citations

Receptor-associated protein (RAP): a specialized chaperone for endocytic receptors.

1998 • 78 citations

Acidosis has no effect on the ATP cost of contraction in cat fast- and slow-twitch skeletal muscles

1997 • 73 citations

Comparative Stability and Clearance of [Met30]Transthyretin and [Met119]Transthyretin

1997 • 70 citations

Localization of retinol-binding protein messenger RNA in the rat kidney and in perinephric fat tissue.

1989 • 66 citations

Plasma and cellular retinoid-binding proteins and transthyretin (prealbumin) are all localized in the islets of Langerhans in the rat.

1985 • 59 citations

Thyroid Hormone Control of Brain and Motor Development: Molecular, Neuroanatomical, and Behavioral Studies

1991 • 55 citations

Immunofunctional properties of a yolk sac epithelial cell line expressing two proteins gp280 and gp330 of the intermicrovillar area of proximal tubule cells: inhibition of endocytosis by the specific antibodies.

1995 • 41 citations

Advances in Perinatal Thyroidology

1991 • 38 citations

Retinoic acid inhibition of thyroxine binding to human transthyretin

1994 • 37 citations

A yellow component associated with human transthyretin has properties like a pterin derivative, 7,8‐dihydropterin‐6‐carboxaldehyde

1995 • 21 citations

Not norepinephrine but its oxidation products bind specifically to plasma proteins.

1991 • 17 citations

Sites of prealbumin production in the human fetus using the indirect immunoperoxidase technique

1985 • 13 citations