Synthetic biomimetic supra molecular Biovector™ (SMBV™) particles for nasal vaccine delivery

Chitosan as a novel nasal delivery system for peptide drugs.

1994 • 628 citations

Adjuvants for human vaccines—current status, problems and future prospects

1995 • 546 citations

Cutting Edge: The Mucosal Adjuvant Cholera Toxin Redirects Vaccine Proteins into Olfactory Tissues

2000 • 365 citations

N-trimethyl chitosan chloride as a potential absorption enhancer across mucosal surfaces: in vitro evaluation in intestinal epithelial cells (Caco-2).

1997 • 243 citations

Evaluation of effect of charge and lipid coating on ability of 60-nm nanoparticles to cross an in vitro model of the blood-brain barrier.

1999 • 178 citations

Positively charged liposome functions as an efficient immunoadjuvant in inducing cell-mediated immune response to soluble proteins

1999 • 144 citations

Phase 1 Evaluation of Intranasal Virosomal Influenza Vaccine with and withoutEscherichia coliHeat-Labile Toxin in Adult Volunteers

1999 • 136 citations

A novel bioadhesive intranasal delivery system for inactivated influenza vaccines

2001 • 133 citations

Heterosubtypic Immunity to Influenza A Virus Infection Requires B Cells but Not CD8⁺Cytotoxic T Lymphocytes

2001 • 119 citations

Nasal-Associated Lymphoid Tissue: Phenotypic and Functional Evidence for the Primary Role of Peripheral Node Addressin in Naive Lymphocyte Adhesion to High Endothelial Venules in a Mucosal Site

1999 • 112 citations

Screening of cationic compounds as an absorption enhancer for nasal drug delivery

1999 • 93 citations

IgA Immunodeficiency Leads to Inadequate Th Cell Priming and Increased Susceptibility to Influenza Virus Infection

2001 • 88 citations

Design, characterization and preclinical efficacy of a cationic lipid adjuvant for influenza split vaccine

2001 • 72 citations

Proofs of the structure of lipid coated nanoparticles (SMBV) used as drug carriers.

2000 • 68 citations

Immunological responses to nasal delivery of free and encapsulated tetanus toxoid: studies on the effect of vehicle volume

1999 • 60 citations

Oral QS-21 Requires Early IL-4 Help for Induction of Mucosal and Systemic Immunity

2001 • 59 citations

Characterisation and phase behaviour of phospholipid bilayers adsorbed on spherical polysaccharidic nanoparticles

1997 • 51 citations

Comparison of the clearance of radiolabelled nose drops and nasal spray as mucosally delivered vaccine

1999 • 43 citations

Humoral and cell-mediated immunity to Vero cell-derived influenza vaccine

2000 • 41 citations

Pattern and load of spontaneous liver metastasis dependent on host immune status studied with a lacZ transduced lymphoma

1994 • 37 citations

Potency of a Genetically Detoxified Mucosal Adjuvant Derived from the Heat‐Labile Enterotoxin ofEscherichia coli(LTK63) Is Not Adversely Affected by the Presence of Preexisting Immunity to the Adjuvant

2001 • 33 citations

Introduction of the haemagglutinin transmembrane region in the influenza virus matrix protein facilitates its incorporation into ISCOM and activation of specific CD8+ cytotoxic T lymphocytes

2000 • 33 citations

Improved oligonucleotide uptake and stability by a new drug carrier, the SupraMolecular BioVector (SMBV)

1997 • 30 citations

Intranasal immunization against influenza virus using polymeric particles

1999 • 28 citations

A new family of carriers (biovectors) enhances the immunogenicity of rabies antigens

1996 • 26 citations

Combination of human cytomegalovirus recombinant immediate-early protein (IE1) with 80 nm cationic biovectors: protection from proteolysis and potentiation of presentation to CD4+ T-cell clones in vitro

1996 • 25 citations

Comparison of in vitro immunostimulatory potential of live and inactivated influenza viruses

2000 • 24 citations

Structural characterization (shape and dimensions) and stability of polysaccharide/lipid nanoparticles

1997 • 21 citations

Stabilization and enhancement of interleukin-2 in vitro bioactivity by new carriers: supramolecular biovectors

1994 • 21 citations

Structural characterization of organized systems of polysaccharides and phospholipids by light scattering spectroscopy and electron microscopy

1997 • 12 citations

The Shape, Dimension and Organisation of Maltodextrins Gel Fragments with and without Associated Phospholipids

1997 • 1 citations