Interaction of the Nck Adapter Protein with p21-activated Kinase (PAK1)

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1994 • 1,520 citations

Site-directed mutagenesis of virtually any plasmid by eliminating a unique site

1992 • 1,089 citations

Structural basis for the binding of proline-rich peptides to SH3 domains

1994 • 1,016 citations

Rho Family GTPases Regulate p38 Mitogen-activated Protein Kinase through the Downstream Mediator Pak1

1995 • 733 citations

SH2 and SH3 domains

1993 • 697 citations

Differential transcriptional activation by Oct-1 and Oct-2: Interdependent activation domains induce Oct-2 phosphorylation

1990 • 696 citations

Cdc42 and PAK-mediated Signaling Leads to Jun Kinase and p38 Mitogen-activated Protein Kinase Activation

1995 • 639 citations

Regulation of Human Leukocyte p21-Activated Kinases Through G Protein—Coupled Receptors

1995 • 415 citations

Identification of a Mouse p21Cdc42/Rac Activated Kinase

1995 • 395 citations

A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20.

1995 • 365 citations

Wiskott-Aldrich Syndrome Protein Physically Associates with Nck through Src Homology 3 Domains

1995 • 315 citations

Actions of Rho Family Small G Proteins and p21-Activated Protein Kinases on Mitogen-Activated Protein Kinase Family Members

1996 • 275 citations

Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway

1996 • 253 citations

Nck, a melanoma cDNA encoding a cytoplasmic protein consisting of the src homology units SH2 and SH3

1990 • 209 citations

Nck associates with the SH2 domain-docking protein IRS-1 in insulin-stimulated cells.

1993 • 207 citations

Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor.

1993 • 189 citations

The SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors.

1992 • 174 citations

Binding of NCK to SOS and Activation of ras-Dependent Gene Expression

1995 • 94 citations

Subcellular localization and quantitation of the major neutrophil pertussis toxin substrate, Gn.

1988 • 94 citations

Phosphorylation of Nek in Response to a Variety of Receptors, Phorbol Myristate Acetate, and Cyclic AMP

1992 • 94 citations

The SH2/SH3 domain-containing protein Nck is recognized by certain anti-phospholipase C-gamma 1 monoclonal antibodies, and its phosphorylation on tyrosine is stimulated by platelet-derived growth factor and epidermal growth factor treatment.

1992 • 88 citations

The SH2- and SH3-containing Nck protein transforms mammalian fibroblasts in the absence of elevated phosphotyrosine levels.

1992 • 85 citations

Molecular Cloning of p125Nap1, a Protein That Associates with an SH3 Domain of Nck

1996 • 64 citations

A Novel Ligand for SH3 Domains

1995 • 43 citations