Systemic Bcl‐2 antisense oligodeoxynucleotide in combination with cisplatin cures EBV⁺ nasopharyngeal carcinoma xenografts in SCID mice

Induction of bcl-2 expression by epstein-barr virus latent membrane protein 1 protects infected B cells from programmed cell death

1991 • 1,195 citations

Quantification of Plasma Epstein–Barr Virus DNA in Patients with Advanced Nasopharyngeal Carcinoma

2004 • 840 citations

Quantitative analysis of cell-free Epstein-Barr virus DNA in plasma of patients with nasopharyngeal carcinoma.

1999 • 749 citations

Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities

2003 • 580 citations

Epstein–Barr virus in the pathogenesis of NPC

2002 • 553 citations

bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice

1998 • 496 citations

Phase I Clinical and Pharmacokinetic Study of Bcl-2 Antisense Oligonucleotide Therapy in Patients With Non-Hodgkin’s Lymphoma

2000 • 460 citations

Nasopharyngeal carcinoma cell line (C666-1) consistently harbouring Epstein-Barr virus

1999 • 380 citations

Antisense therapy for cancer

2005 • 353 citations

Molecular prognostication of nasopharyngeal carcinoma by quantitative analysis of circulating Epstein-Barr virus DNA.

2000 • 333 citations

Oblimersen Bcl-2 Antisense: Facilitating Apoptosis in Anticancer Treatment

2002 • 278 citations

Antitumor applications of stimulating toll-like receptor 9 with CpG oligodeoxynucleotides

2004 • 201 citations

Bcl‐2 proto‐oncogene expression in epstein‐barr‐virus‐associated nasopharyngeal carcinoma

1993 • 198 citations

The significance of LMP1 expression in nasopharyngeal carcinoma

2002 • 189 citations

Chemosensitization and Delayed Androgen-Independent Recurrence of Prostate Cancer With the Use of Antisense Bcl-2 Oligodeoxynucleotides

2000 • 185 citations

Epstein-barr virus latent membrane protein 1: Structure and functions

2003 • 179 citations

Eradication of human non-Hodgkin's lymphoma in SCID mice by BCL-2 antisense oligonucleotides combined with low-dose cyclophosphamide.

2000 • 107 citations

Analysis of bcl-2 expression in normal, inflamed, dysplastic nasopharyngeal epithelia, and nasopharyngeal carcinoma: Association with p53 expression

1997 • 66 citations

Bcl-2 antisense oligonucleotides chemosensitize human gastric cancer in a SCID mouse xenotransplantation model

2001 • 60 citations

Pathogenesis and treatment of nasopharyngeal carcinoma

2004 • 54 citations

Treatment of melanoma cells with a bcl-2/bcl-xL antisense oligonucleotide induces antiangiogenic activity

2003 • 54 citations

Implication of macrophages in tumor rejection induced by CpG-oligodeoxynucleotides without antigen.

2001 • 47 citations

Antisense RNA Down-Regulation of bcl-2 Expression in DU145 Prostate Cancer Cells Does Not Diminish the Cytostatic Effects of G3139 (Oblimersen)

2004 • 47 citations

Bcl-2 and LMP1 expression in nasopharyngeal carcinomas

2001 • 40 citations

Bcl-2 antisense oligodeoxynucleotide therapy of Epstein-Barr virus-associated lymphoproliferative disease in severe combined immunodeficient mice.

2000 • 38 citations

Bcl-2 antisense (G3139, Genasense) enhances the in vitro and in vivo response of Epstein-Barr virus-associated lymphoproliferative disease to rituximab.

2003 • 37 citations

Co-expression of p53 and bcl-2 may correlate to the presence of Epstein–Barr virus genome and the expression of proliferating cell nuclear antigen in nasopharyngeal carcinoma

2000 • 37 citations

Significance of c-Myc and Bcl-2 Protein Expression in Nasopharyngeal Carcinoma

2003 • 35 citations

Antitumor Effect of G3139 Bcl-2 Antisense Oligonucleotide Is Independent of Its Immune Stimulation by CpG Motifs in SCID Mice

2002 • 32 citations

Association of p53 and BCL‐2 expression with Epstein‐Barr virus infection in the cancers of head and neck

2001 • 30 citations

Antitumor Efficacy of Oblimersen Bcl-2 Antisense Oligonucleotide Alone and in Combination with Vinorelbine in Xenograft Models of Human Non–Small Cell Lung Cancer

2004 • 29 citations

Combined treatment of Bcl‐2 antisense oligodeoxynucleotides (G3139), p‐glycoprotein inhibitor (PSC833), and sterically stabilized liposomal doxorubicin suppresses growth of drug‐resistant growth of drug‐resistant breast cancer in severely combined immunodeficient mice

2003 • 23 citations

Enhanced antitumour efficacy of gimatecan in combination with Bcl-2 antisense oligonucleotide in human melanoma xenografts

2005 • 20 citations

CpG Oligonucleotides Elicit Antitumor Responses in a Human Melanoma NOD/SCID Xenotransplantation Model

2004 • 20 citations

Expression of Epstein-Barr virus latent membrane protein 1 and B-cell leukemia-lymphoma 2 gene in nasopharyngeal carcinoma tissues.

2002 • 7 citations