The effect of ethanol-induced CYP2E1 on proteasome activity: the role of 4-hydroxynonenal

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

1991 • 6,550 citations

Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease.

1996 • 976 citations

Purification of two high molecular weight proteases from rabbit reticulocyte lysate.

1987 • 542 citations

The Axial Channel of the Proteasome Core Particle Is Gated by the Rpt2 ATPase and Controls Both Substrate Entry and Product Release

2001 • 413 citations

Reactions of 4-hydroxynonenal with proteins and cellular targets

2004 • 391 citations

Oxidative Modification and Inactivation of the Proteasome during Coronary Occlusion/Reperfusion

2001 • 349 citations

4-Hydroxy-2-nonenal-mediated Impairment of Intracellular Proteolysis during Oxidative Stress

1999 • 320 citations

Role of cytochrome P4502E1-dependent formation of hydroxyethyl free radical in the development of liver damage in rats intragastrically fed with ethanol

1996 • 278 citations

Inhibition of the multicatalytic proteinase (proteasome) by 4‐hydroxy‐2‐nonenal cross‐linked protein

1997 • 264 citations

Inhibition of Ethanol-Induced Liver Disease in the Intragastric Feeding Rat Model by Chlormethiazole

2000 • 165 citations

Modulation of experimental alcohol-induced liver disease by cytochrome P450 2E1 inhibitors

1995 • 164 citations

Effect of Ethanol on Cytochrome P450 2E1 (CYP2E1), Lipid Peroxidation, and Serum Protein Adduct Formation in Relation to Liver Pathology Pathogenesis

1993 • 144 citations

Lipid peroxidation contributes to immune reactions associated with alcoholic liver disease

2002 • 141 citations

Oxidative Stress Is Found in Amyloid Deposits in Systemic Amyloidosis

1997 • 134 citations

Ethanol-induced free radicals and hepatic DNA strand breaks are prevented in vivo by antioxidants: effects of acute and chronic ethanol exposure

2000 • 132 citations

Effects of Chronic Ethanol Administration on Rat Liver Proteasome Activities: Relationship With Oxidative Stress

1999 • 130 citations

Chemical Characterization of a Protein-4-hydroxy-2-nonenal Cross-Link: Immunochemical Detection in Mitochondria Exposed to Oxidative Stress

1996 • 120 citations

The Effect of Ethanol-Induced Cytochrome p4502E1 on the Inhibition of Proteasome Activity by Alcohol

2000 • 107 citations

Microsomal lipid peroxidation: The role of NADPH — Cytochrome P450 reductase and cytochrome P450

1990 • 103 citations

Lipid Peroxidation, CYP2E1 and Arachidonic Acid Metabolism in Alcoholic Liver Disease in Rats

1997 • 99 citations

Hydroxyethyl radicals in ethanol hepatotoxicity

1999 • 97 citations

Acetaldehyde-modified and 4-hydroxynonenal-modified proteins in the livers of rats with alcoholic liver disease

1997 • 86 citations

Peptidase activities of the multicatalytic protease in rat liver after voluntary and intragastric ethanol administration

1998 • 73 citations

Quaternary Structure of the ATPase Complex of Human 26S Proteasomes Determined by Chemical Cross-Linking

2001 • 72 citations

The importance of cycling of blood alcohol levels in the pathogenesis of experimental alcoholic liver disease in rats

2002 • 69 citations

CYP-2E1 inhibitors partially ameliorate the changes in hepatic fatty acid composition induced in rats by chronic administration of ethanol and a high fat diet.

1995 • 67 citations

Lipid Composition of RBC Ghosts, Liver Mitochondria and Microsomes of Ethanol-Fed Rats

1970 • 55 citations

Lipid composition of RBC ghosts, liver mitochondria and microsomes of ethanol-fed rats.

1970 • 52 citations

Mechanism of the alcohol cyclic pattern: role of the hypothalamic-pituitary-thyroid axis

2000 • 48 citations

Modulation of experimental alcohol-induced liver disease by cytochrome P450 2E1 inhibitors*1

1995 • 48 citations

Ethanol withdrawal induced CYP2E1 degradation in vivo, blocked by proteasomal inhibitor PS-341 1 1This article is part of a series of reviews on “Alcohol, Oxidative Stress and Cell Injury”. The full list of papers may be found on the homepage of the journal.

2002 • 36 citations

Selective chemical inactivation of AAA proteins reveals distinct functions of proteasomal ATPases

2001 • 13 citations