Temporal Correlation Mapping Analysis of the Hemodynamic Penumbra in Mutant Mice Deficient in Endothelial Nitric Oxide Synthase Gene Expression

Nitric oxide: physiology, pathophysiology, and pharmacology.

1991 • 15,563 citations

Hypertension in mice lacking the gene for endothelial nitric oxide synthase

1995 • 2,075 citations

Effects of Cerebral Ischemia in Mice Deficient in Neuronal Nitric Oxide Synthase

1994 • 1,578 citations

Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase

1995 • 1,454 citations

Targeted disruption of the neuronal nitric oxide synthase gene

1993 • 1,300 citations

Role of Oxidants in Ischemic Brain Damage

1996 • 1,037 citations

A novel neuronal messenger molecule in brain: The free radical, nitric oxide

1992 • 837 citations

Enlarged Infarcts in Endothelial Nitric Oxide Synthase Knockout Mice are Attenuated by Nitro-L-Arginine

1996 • 713 citations

Nitric Oxide Synthase Inhibition and Cerebrovascular Regulation

1994 • 669 citations

Cerebral blood flow determination by rapid-sequence computed tomography: theoretical analysis.

1980 • 620 citations

Nitric oxide and the cerebral circulation.

1994 • 540 citations

Theoretical Basis of Indicator-Dilution Methods For Measuring Flow and Volume

1962 • 510 citations

Reduced Brain Edema and Infarction Volume in Mice Lacking the Neuronal Isoform of Nitric Oxide Synthase after Transient MCA Occlusion

1996 • 422 citations

Pitfalls in MR measurement of tissue blood flow with intravascular tracers: Which mean transit time?

1993 • 338 citations

The NOS Inhibitor, 7-Nitroindazole, Decreases Focal Infarct Volume but Not the Response to Topical Acetylcholine in Pial Vessels

1994 • 298 citations

L-arginine infusion promotes nitric oxide-dependent vasodilation, increases regional cerebral blood flow, and reduces infarction volume in the rat.

1994 • 233 citations

Dynamic Penumbra Demonstrated by Sequential Multitracer PET after Middle Cerebral Artery Occlusion in Cats

1994 • 232 citations

Nitric oxide: foe or friend to the injured brain?

1993 • 212 citations

Nitric Oxide Donors Increase Blood Flow and Reduce Brain Damage in Focal Ischemia: Evidence That Nitric Oxide is Beneficial in the Early Stages of Cerebral Ischemia

1994 • 206 citations

The Complex Role of Nitric Oxide in the Pathophysiology of Focal Cerebral Ischemia

1994 • 176 citations

Nitric oxide and focal cerebral ischemia: multiplicity of actions and diverse outcome.

1994 • 144 citations

<scp>l</scp>‐Arginine dilates rat pial arterioles by nitric oxide‐dependent mechanisms and increases blood flow during focal cerebral ischaemia

1992 • 120 citations

Combined Perfusion and Diffusion-Weighted Magnetic Resonance Imaging in a Rat Model of Reversible Middle Cerebral Artery Occlusion

1995 • 90 citations

Temporal Correlation Analysis of Penumbral Dynamics in Focal Cerebral Ischemia

1996 • 31 citations

Applications of similarity mapping in dynamic MRI

1995 • 29 citations

Hemodynamic alterations in focal cerebral ischemia: Temporal correlation analysis for functional imaging

1996 • 10 citations

Therapeutic Potential of L-Arginine, a Precursor of Nitric Oxide, in Focal Cerebral Ischemia

1994 • 9 citations