Crystal Structure of Escherichia coli MscS, a Voltage-Modulated and Mechanosensitive Channel

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1997 • 33,348 citations

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

A quantitative description of membrane current and its application to conduction and excitation in nerve

1952 • 21,965 citations

The CCP4 suite: programs for protein crystallography

1994 • 17,203 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

The Structure of the Potassium Channel: Molecular Basis of K ⁺ Conduction and Selectivity

1998 • 6,595 citations

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

1991 • 5,267 citations

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1997 • 3,784 citations

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1997 • 1,905 citations

HOLE: A program for the analysis of the pore dimensions of ion channel structural models

1996 • 1,631 citations

Crystal structure and mechanism of a calcium-gated potassium channel

2002 • 1,338 citations

A rapid finite difference algorithm, utilizing successive over‐relaxation to solve the Poisson–Boltzmann equation

1991 • 1,257 citations

The open pore conformation of potassium channels

2002 • 1,192 citations

Structure of the MscL Homolog from Mycobacterium tuberculosis : A Gated Mechanosensitive Ion Channel

1998 • 972 citations

The Voltage Sensor in Voltage-Dependent Ion Channels

2000 • 854 citations

A large-conductance mechanosensitive channel in E. coli encoded by mscL alone

1994 • 701 citations

Protection of Escherichia coli cells against extreme turgor by activation of MscS and MscL mechanosensitive channels: identification of genes required for MscS activity

1999 • 701 citations

Pressure-sensitive ion channel in Escherichia coli.

1987 • 646 citations

Physical principles underlying the transduction of bilayer deformation forces during mechanosensitive channel gating

2002 • 644 citations

Open channel structure of MscL and the gating mechanism of mechanosensitive channels

2002 • 596 citations

Superconducting Single Crystals of Tl2Ba2CaCu2O8 and YBa2Cu4O8: Crystal Structures in the Vicinity of Tc

1998 • 543 citations

Transmembrane Movement of the Shaker K+ Channel S4

1996 • 496 citations

Nicotinic acetylcholine receptor at 4.6 Å resolution: transverse tunnels in the channel 1 1Edited by J. Karn

1999 • 487 citations

Atomic scale movement of the voltage-sensing region in a potassium channel measured via spectroscopy

1999 • 466 citations

Evidence for voltage-dependent S4 movement in sodium channels

1995 • 396 citations

Lateral Pressures in Cell Membranes: A Mechanism for Modulation of Protein Function

1997 • 356 citations

The gating mechanism of the large mechanosensitive channel MscL

2001 • 350 citations

Two types of mechanosensitive channels in the Escherichia coli cell envelope: solubilization and functional reconstitution

1993 • 321 citations

Mechanoelectrical Transduction by Hair Cells

1988 • 310 citations

MECHANOSENSITIVE CHANNELS OFESCHERICHIA COLI:The MscL Gene, Protein, and Activities

1997 • 287 citations

Spectroscopic mapping of voltage sensor movement in the Shaker potassium channel

1999 • 276 citations

Purification of the Small Mechanosensitive Channel of Escherichia coli (MscS): the Subunit Structure, Conduction, and Gating Characteristicsin Liposomes

2002 • 266 citations

The voltage-sensitive sodium channel is a bell-shaped molecule with several cavities

2001 • 254 citations

A novel method for structure-based prediction of ion channel conductance properties

1997 • 224 citations

Voltage-Dependent Proton Transport by the Voltage Sensor of the Shaker K+ Channel

1997 • 224 citations

Structural Models of the MscL Gating Mechanism

2001 • 213 citations

Gadolinium ion inhibits loss of metabolites induced by osmotic shock and large stretch‐activated channels in bacteria

1992 • 205 citations

Specificity and promiscuity in membrane helix interactions

1994 • 199 citations

Structure of the KcsA channel intracellular gate in the open state.

2001 • 196 citations

Three-Dimensional Structure of a Voltage-Gated Potassium Channel at 2.5 nm Resolution

2001 • 141 citations

A patch‐clamp study of ion channels of inner and outer membranes and of contact zones of E. coli, fused into giant liposomes

1989 • 111 citations

Site-Directed Spin-Labeling Analysis of Reconstituted Mscl in the Closed State

2001 • 103 citations

Characterization of mechanosensitive channels in Escherichia coli cytoplasmic membrane by whole-cell patch clamp recording

1995 • 102 citations

Conformational pathways in the gating of Escherichia coli mechanosensitive channel

2002 • 83 citations

Functional Design of Bacterial Mechanosensitive Channels

2002 • 80 citations

Common evolutionary origins of mechanosensitive ion channels in Archaea, Bacteria and cell-walled Eukarya

2001 • 72 citations

Analysis of the kefA2 mutation suggests that KefA is a cation‐specific channel involved in osmotic adaptation in Escherichia coli

2002 • 68 citations

The α-Helix and the Organization and Gating of Channels

2002 • 67 citations

The crystal structure of Tm₅Re₂O₁₂

1999 • 51 citations

Crystallographic Analyses of Ion Channels: Lessons and Challenges

2000 • 44 citations

Effect of Mutation of Potassium-Efflux System, KefA, on Mechanosensitive Channels in the Cytoplasmic Membrane of Escherichia coli

1996 • 33 citations