Analysis of the kefA2 mutation suggests that KefA is a cation‐specific channel involved in osmotic adaptation in Escherichia coli

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Experiments in molecular genetics

1972 • 28,260 citations

Escherichia coli and Salmonella typhimurium: Cellular and molecular biology

1988 • 3,957 citations

Data for Biochemical Research.

1969 • 1,308 citations

Multidrug efflux pumps of gram-negative bacteria

1996 • 1,071 citations

Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export

2000 • 1,052 citations

Structure of the MscL Homolog from Mycobacterium tuberculosis : A Gated Mechanosensitive Ion Channel

1998 • 972 citations

A large-conductance mechanosensitive channel in E. coli encoded by mscL alone

1994 • 701 citations

Protection of Escherichia coli cells against extreme turgor by activation of MscS and MscL mechanosensitive channels: identification of genes required for MscS activity

1999 • 701 citations

Analysis of the regulation of Escherichia coli alkaline phosphatase synthesis using deletions and φ80 transducing phages

1975 • 489 citations

Biochemical and genetic characterization of osmoregulatory trehalose synthesis in Escherichia coli

1988 • 390 citations

Transient accumulation of potassium glutamate and its replacement by trehalose during adaptation of growing cells of Escherichia coli K-12 to elevated sodium chloride concentrations

1988 • 389 citations

Potassium Transport Loci in Escherichia coli K-12

1971 • 381 citations

Calcium-activated potassium channels

1987 • 342 citations

Na+/H+ antiporters

2001 • 337 citations

Genetic Recombination in Escherichia coli: The Role of Exonuclease I

1971 • 330 citations

Osmoregulation in Escherichia coli by accumulation of organic osmolytes: betaines, glutamic acid, and trehalose

1987 • 301 citations

MECHANOSENSITIVE CHANNELS OFESCHERICHIA COLI:The MscL Gene, Protein, and Activities

1997 • 287 citations

Mutations that alter the signal sequence of alkaline phosphatase in Escherichia coli

1983 • 281 citations

Interplay between Efflux Pumps May Provide Either Additive or Multiplicative Effects on Drug Resistance

2000 • 260 citations

Osmoregulation of gene expression in Salmonella typhimurium: proU encodes an osmotically induced betaine transport system

1985 • 255 citations

Regulation of compatible solute accumulation in bacteria

1998 • 251 citations

Chapter 3 Analysis of Membrane Protein Topology Using Alkaline Phosphatase and β-Galactosidase Gene Fusions

1991 • 231 citations

Interdependence of K+ and glutamate accumulation during osmotic adaptation of Escherichia coli.

1994 • 228 citations

Linkage Map of Escherichia coli K-12, Edition 10: The Traditional Map

1998 • 220 citations

Gadolinium ion inhibits loss of metabolites induced by osmotic shock and large stretch‐activated channels in bacteria

1992 • 205 citations

Salmonella typhimurium proP gene encodes a transport system for the osmoprotectant betaine

1985 • 197 citations

Multiple Mechanosensitive Ion Channels from Escherichia coli, Activated at Different Thresholds of Applied Pressure

1996 • 196 citations

pHG165: A pBR322 copy number derivative of pUC8 for cloning and expression

1986 • 195 citations

One face of a transmembrane helix is crucial in mechanosensitive channel gating

1998 • 194 citations

Single residue substitutions that change the gating properties of a mechanosensitive channel in Escherichia coli.

1996 • 194 citations

Membrane topology and multimeric structure of a mechanosensitive channel protein of Escherichia coli.

1996 • 177 citations

Outer membrane protein e of Escherichia coli K-12 is co-regulated with alkaline phosphatase

1980 • 167 citations

Genetic analysis of potassium transport loci in Escherichia coli: evidence for three constitutive systems mediating uptake potassium

1991 • 164 citations

Managing hypoosmotic stress: Aquaporins and medianosensitive channels in Escherichia coli

1999 • 138 citations

Na+-activated K+ channels: a new family of large-conductance ion channels

1994 • 135 citations

Functional and structural conservation in the mechanosensitive channel MscL implicates elements crucial for mechanosensation

1998 • 133 citations

Mutations in a Bacterial Mechanosensitive Channel Change the Cellular Response to Osmotic Stress

1997 • 122 citations

The role of peptide metabolism in the growth of Listeria monocytogenes ATCC 23074 at high osmolarity

1995 • 116 citations

Turgor-controlled K+ fluxes and their pathways in Escherichia coli

1985 • 111 citations

Characterization of mechanosensitive channels in Escherichia coli cytoplasmic membrane by whole-cell patch clamp recording

1995 • 102 citations

Chemically Charging the Pore Constriction Opens the Mechanosensitive Channel MscL

2001 • 100 citations

Regulation of compatible solute accumulation in Salmonella typhimurium: evidence for a glycine betaine efflux system

1991 • 95 citations

The relationship between intracellular pH, the pH gradient and potassium transport in Escherichia coli

1983 • 95 citations

Periplasmic protein associated with the oligopeptide permeases of Salmonella typhimurium and Escherichia coli

1983 • 82 citations

Multiple mechanisms contribute to osmotic inducibility of proU operon expression in Escherichia coli: demonstration of two osmoresponsive promoters and of a negative regulatory element within the first structural gene

1991 • 81 citations

Two different Escherichia coli proP promoters respond to osmotic and growth phase signals

1995 • 73 citations

Enteric bacteria and osmotic stress: an integrated homeostatic system

1988 • 57 citations

Cosmid-derived map ofE.colistrain BHB2600 in comparison to the map of strain W3110

1989 • 37 citations

Effect of Mutation of Potassium-Efflux System, KefA, on Mechanosensitive Channels in the Cytoplasmic Membrane of Escherichia coli

1996 • 33 citations

Enteric bacteria and osmotic stress: an integrated homeostatic system

1988 • 7 citations