CD4‐negative cytotoxic T cells with a T cell receptor α/β^intermediate expression in CD8‐deficient mice

T-cell antigen receptor genes and T-cell recognition

1988 • 3,099 citations

"Infectious" Transplantation Tolerance

1993 • 890 citations

Normal Development of Mice Deficient in β ₂ M, MCClass I Proteins, and CD8 ⁺ T Cells

1990 • 885 citations

Mice lacking MHC class II molecules

1991 • 869 citations

Negative selection of lymphocytes

1994 • 810 citations

Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4

1991 • 695 citations

Positive selection of lymphocytes

1994 • 563 citations

CD8 is needed for development of cytotoxic T but not helper T cells

1991 • 528 citations

Positive and Negative Thymocyte Selection Induced by Different Concentrations of a Single Peptide

1994 • 497 citations

Rejection of class I MHC-deficient haemopoietic cells by irradiated MHC-matched mice

1991 • 419 citations

Molecular Biology and Function of CD4 and CD8

1989 • 388 citations

SEROLOGICALLY DEFINED AND LYMPHOCYTE-DEFINED COMPONENTS OF THE MAJOR HISTOCOMPATIBILITY COMPLEX IN THE MOUSE

1972 • 293 citations

Does T-cell tolerance require a dedicated antigen-presenting cell?

1989 • 288 citations

Helper T cells without CD4: control of leishmaniasis in CD4-deficient mice

1993 • 275 citations

Reentry of T cells to the adult thymus is restricted to activated T cells.

1991 • 263 citations

CD8 modulation of T-cell antigen receptor–ligand interactions on living cytotoxic T lymphocytes

1995 • 245 citations

Properties of purified T cell subsets. II. In vivo responses to class I vs. class II H-2 differences.

1986 • 229 citations

Indirect recognition by helper cells can induce donor-specific cytotoxic T lymphocytes in vivo.

1994 • 227 citations

CELL-MEDIATED LYMPHOLYSIS

1973 • 225 citations

MECHANISMS OF T CELL RECOGNITION OF ALLOANTIGEN

1994 • 205 citations

Phenotype, specificity, and function of T cell subsets and T cell interactions involved in skin allograft rejection.

1987 • 198 citations

GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO

1974 • 177 citations

Role of CD4 and CD8 in T Cell Activation and Differentiation

1993 • 172 citations

LCMV-Specific, Class II-Restricted Cytotoxic T Cells in β2-Microglobulin-Deficient Mice

1992 • 164 citations

T-cell specificity for H–2 and Ir gene phenotype correlates with the phenotype of thymic antigen-presenting cells

1980 • 153 citations

Skin graft rejection by beta 2-microglobulin-deficient mice.

1992 • 142 citations

The fate of CD4-8- T cell receptor-alpha beta+ thymocytes.

1991 • 129 citations

Recognition structures on natural killer cells

1993 • 123 citations

CD8 surface levels alter the fate of alpha/beta T cell receptor-expressing thymocytes in transgenic mice.

1992 • 119 citations

Cellular Components of Allograft Rejection: Identity, Specificity, and Cytotoxic Function of Cells Infiltrating Acutely Rejecting Allografts

1977 • 110 citations

Alloreactive cytotoxic T cells can develop and function in mice lacking both CD4 and CD8

1993 • 101 citations

SECONDARY MALIGNANCIES AFTER MARROW TRANSPLANTATION FOR LEUKEMIA OR APLASTIC ANEMIA

1994 • 77 citations

Antigen-presenting cells for unprimed T cells

1989 • 74 citations

CD8 is needed for positive selection but differentially required for negative selection of T cells during thymic ontogeny

1993 • 71 citations

Development of αβ T cells

1993 • 56 citations

Evidence for involvement of dual-function T cells in rejection of MHC class I disparate skin grafts. Assessment of MHC class I alloantigens as in vivo helper determinants.

1988 • 47 citations

Avidity for antigen can influence the helper dependence of CD8+ T lymphocytes.

1993 • 43 citations

Characterization of V_β‐bearing cells in athymic (nu/nu) mice suggests an extrathymic pathway for T cell differentiation

1990 • 41 citations

Monoclonal antibodies for the induction of transplantation tolerance

1993 • 29 citations

Is CD8 dependence a true reflection of TCR affinity for antigen?

1993 • 25 citations

IMMUNE MECHANISMS IN ORGAN ALLOGRAFT REJECTION

1985 • 24 citations

In Vivo Responses of Alloreactive Lymphocytes Stimulated In Vitro

1977 • 15 citations

Increased number of cytotoxic T cells within CD4+8− T cells in β2-microglobulin, major histocompatibility complex class I-deficient mice

1993 • 12 citations

Equivalent helper functions of human “naive” and “memory” CD4+ T cells for the generation of alloreactive cytotoxic T lymphocytes

1990 • 6 citations