Soluble Fas ligand released by colon adenocarcinoma cells induces host lymphocyte apoptosis: an active mode of immune evasion in colon cancer

The Fas Death Factor

1995 • 4,070 citations

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

1995 • 2,028 citations

A role for CD95 ligand in preventing graft rejection

1995 • 1,184 citations

Fas ligand mediates activation-induced cell death in human T lymphocytes.

1995 • 949 citations

Lymphocyte apoptosis induced by CD95 (APO–1/Fas) ligand–expressing tumor cells — A mechanism of immune evasion?

1996 • 917 citations

The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand.

1996 • 894 citations

Fas ligand in human serum

1996 • 682 citations

Downregulation of Fas ligand by shedding

1998 • 681 citations

CD95 ligand (FasL)-induced apoptosis is necessary for corneal allograft survival.

1997 • 375 citations

Soluble Fas Ligand Induces Epithelial Cell Apoptosis in Humans with Acute Lung Injury (ARDS)

1999 • 358 citations

The Fas Counterattack In Vivo: Apoptotic Depletion of Tumor-Infiltrating Lymphocytes Associated with Fas Ligand Expression by Human Esophageal Carcinoma

1998 • 331 citations

Fas ligand is positioned in mouse uterus and placenta to prevent trafficking of activated leukocytes between the mother and the conceptus.

1997 • 291 citations

The Role of APO‐1‐Mediated Apoptosis in the Immune System

1994 • 242 citations

Cotransplantation of Allogeneic Islets With Allogeneic Testicular Cell Aggregates Allows Long-Term Graft Survival Without Systemic Immunosuppression

1997 • 222 citations

Characterization of Fas (Apo-1, CD95)-Fas Ligand Interaction

1997 • 193 citations

Soluble HLA Class I, HLA Class II, and Fas Ligand in Blood Components: A Possible Key to Explain the Immunomodulatory Effects of Allogeneic Blood Transfusions

1999 • 163 citations

Expression of Fas ligand by human gastric adenocarcinomas: a potential mechanism of immune escape in stomach cancer

1999 • 125 citations

Fas ligand expression in primary colon adenocarcinomas: evidence that the Fas counterattack is a prevalent mechanism of immune evasion in human colon cancer

1998 • 122 citations

Soluble HLA Class I, HLA Class II, and Fas Ligand in Blood Components: A Possible Key to Explain the Immunomodulatory Effects of Allogeneic Blood Transfusions

1999 • 111 citations

An aggressive nasal lymphoma accompanied by high levels of soluble Fas ligand

1996 • 76 citations

Fas ligand is constitutively secreted by prostate cancer cells in vitro.

1998 • 69 citations

Levels of soluble Fas ligand in myocarditis

1998 • 66 citations

Malaria Infection Induces Rapid Elevation of the Soluble Fas Ligand Level in Serum and Subsequent T Lymphocytopenia: Possible Factors Responsible for the Differences in Susceptibility of Two Species ofMacacaMonkeys toPlasmodium coatneyiInfection

2000 • 61 citations

CD95(APO-1/Fas)-Mediated Apoptosis in Normal and Malignant Liver, Colon, and Hematopoietic Cells

1998 • 56 citations

Levels of soluble FasL and FasL gene expression during the development of graft-versus-host disease in DLT-treated patients

1999 • 47 citations

Fas ligand expression in esophageal carcinomas and their lymph node metastases

2000 • 45 citations

Elevated serum soluble Fas ligand in natural killer cell proliferative disorders

1998 • 43 citations

Requirement of Cell–Cell Contact in the Induction of Jurkat T Cell Apoptosis: The Membrane-Anchored but Not Soluble Form of FasL Can Trigger Anti-CD3-Induced Apoptosis in Jurkat T Cells

1997 • 38 citations

Kupffer cells of cirrhotic rat livers sensitize colon cancer cells to Fas-mediated apoptosis

2001 • 33 citations

Oligoclonal T cells in human cancer

1998 • 22 citations

Soluble Fas ligand expression in the ocular fluids of uveitis patients

2000 • 20 citations

Clinical significance of serum soluble Fas ligand in patients with acute self-limited and fulminant hepatitis.

1998 • 19 citations

Liver dysfunction due to apoptosis in a patient with systemic lupus erythematosus

2000 • 19 citations

Comparison of the Effects of Immunosuppressive Factors from Newly Established Colon Carcinoma Cell Cultures on Human Lymphocyte Proliferation and Cytokine Secretion

2000 • 19 citations

Increased Levels of Soluble Fas Receptor and Fas Ligand in the Cerebrospinal Fluid of HIV-Infected Patients

2000 • 19 citations

Increased levels of soluble Fas ligand in CSF of rapidly progressive HTLV-1-associated myelopathy/tropical spastic paraparesis patients

1999 • 18 citations

Soluble fas ligand in natural killer cell lymphoma

1999 • 11 citations

Modulations of the effector function and cytokine production of human lymphocytes by secreted factors derived from colorectal-carcinoma cells

1997 • 10 citations

[Increased serum soluble Fas ligand in hyperthyroid Graves' disease].

1999 • 8 citations

Preoperative lymphocyte counts in peripheral blood in patients with colorectal neoplasms

1979 • 7 citations