Increased Levels of Soluble Fas Receptor and Fas Ligand in the Cerebrospinal Fluid of HIV-Infected Patients

NF-kB: a crucial transcription factor for glial and neuronal cell function

1997 • 1,005 citations

Metalloproteinase-mediated release of human Fas ligand.

1995 • 835 citations

Immunocytochemical quantitation of human immunodeficiency virus in the brain: Correlations with dementia

1995 • 663 citations

Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction

1997 • 453 citations

Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals.

1995 • 438 citations

Caspase 1-independent IL-1β release and inflammation induced by the apoptosis inducer Fas ligand

1998 • 377 citations

Upregulation of Fas ligand expression by human immunodeficiency virus in human macrophages mediates apoptosis of uninfected T lymphocytes

1996 • 316 citations

Involvement of the CD95 (APO-1/Fas) receptor/ligand system in multiple sclerosis brain.

1996 • 283 citations

Fas ligand and Fas are expressed constitutively in human astrocytes and the expression increases with IL-1, IL-6, TNF-alpha, or IFN-gamma.

1999 • 174 citations

Chemotactic activity of soluble Fas ligand against phagocytes.

1998 • 159 citations

Role of Fas Ligand and Receptor in the Mechanism of T-Cell Depletion in Acquired Immunodeficiency Syndrome: Effect on CD4+ Lymphocyte Depletion and Human Immunodeficiency Virus Replication

1997 • 159 citations

CD95 (Fas/Apo-1) as a Receptor Governing Astrocyte Apoptotic or Inflammatory Responses: A Key Role in Brain Inflammation?

1999 • 149 citations

TNF-α and IFN-γ render microglia sensitive to Fas ligand-induced apoptosis by induction of Fas expression and down-regulation of Bcl-2 and Bcl-xL

1998 • 144 citations

Fas Ligand and Fas Are Expressed Constitutively in Human Astrocytes and the Expression Increases with IL-1, IL-6, TNF-α, or IFN-γ

1999 • 142 citations

Fas antigen expression in brains of patients with Alzheimer-type dementia

1995 • 132 citations

Cutting Edge: Chemotactic Activity of Soluble Fas Ligand Against Phagocytes

1998 • 123 citations

The soluble form of Fas molecule is elevated in parkinsonian brain tissues

1996 • 101 citations

Fas expression on human fetal astrocytes without susceptibility to fas-mediated cytotoxicity

1998 • 79 citations

Fas/Apo-1 activates nuclear factor kappa B and induces interleukin-6 production.

1995 • 77 citations

Membrane and Soluble Forms of Fas (CD95) and Fas Ligand in Peripheral Blood Mononuclear Cells and in Plasma from Human Immunodeficiency Virus‐Infected Persons

1998 • 72 citations

Fas (CD95) expression on CD4+ T cells from HIV-infected patients increases with disease progression

1995 • 71 citations

Progressive B Cell Apoptosis and Expression of Fas Ligand during Human Immunodeficiency Virus Type 1 Infection

1997 • 65 citations

CD95–CD95L: can the brain learn from the immune system?

1998 • 65 citations

Fas-Mediated Stimulation Induces IL-8 Secretion by Rheumatoid Arthritis Synoviocytes Independently of CPP32-Mediated Apoptosis

1996 • 65 citations

Detectable concentrations of Fas ligand in cerebrospinal fluid after severe head injury

1997 • 59 citations

Detection of the soluble form of the Fas molecule in patients with multiple sclerosis and human T-lymphotropic virus type I-associated myelopathy

1997 • 47 citations

Elevated serum levels of soluble Fas/APO-1 in human immunodeficiency virus-infected individuals [letter]

1996 • 24 citations

Concentrations of soluble CD95 and CD8 antigens in the plasma and levels of CD8+CD95+, CD8+CD38+, and CD4+CD95+ T cells are markers for HIV-1 infection and clinical status.

1997 • 22 citations

TNF-α and IFN-γ render microglia sensitive to Fas ligand-induced apoptosis by induction of Fas expression and down-regulation of Bcl-2 and Bcl-xL

1998 • 6 citations