Global analysis of gene expression patterns during disuse atrophy in rat skeletal muscle

Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing

1995 • 93,704 citations

Cluster analysis and display of genome-wide expression patterns

1998 • 16,410 citations

Identification of Ubiquitin Ligases Required for Skeletal Muscle Atrophy

2001 • 3,292 citations

Expression monitoring by hybridization to high-density oligonucleotide arrays

1996 • 2,796 citations

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

2001 • 2,539 citations

Double muscling in cattle due to mutations in the myostatin gene

1997 • 1,970 citations

Identifying differentially expressed genes using false discovery rate controlling procedures

2003 • 1,741 citations

Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy

2001 • 1,714 citations

Regulation of myostatin activity and muscle growth

2001 • 1,536 citations

Metallothionein: the multipurpose protein

2002 • 1,262 citations

Handbook of Physiology. Section 12. Exercise: Regulation and Integration of Multiple Systems

1997 • 915 citations

Regulation of elongation factor 2 kinase by p90RSK1 and p70 S6 kinase

2001 • 772 citations

Atrophy of the soleus muscle by hindlimb unweighting

1990 • 632 citations

Gigantism in mice lacking suppressor of cytokine signalling-2

2000 • 492 citations

Vitamin D3 Up-Regulated Protein 1 Mediates Oxidative Stress Via Suppressing the Thioredoxin Function

2000 • 480 citations

Overexpression of Id protein inhibits the muscle differentiation program: in vivo association of Id with E2A proteins.

1992 • 480 citations

Fibronectin, integrins, and growth control

2001 • 452 citations

Invited Review: Redox modulation of skeletal muscle contraction: what we know and what we don't

2001 • 449 citations

The Myostatin Propeptide and the Follistatin-related Gene Are Inhibitory Binding Proteins of Myostatin in Normal Serum

2002 • 439 citations

Antioxidants and oxidants regulated signal transduction pathways

2002 • 437 citations

Analysis of high density expression microarrays with signed-rank call algorithms

2002 • 431 citations

What do we really know about the ubiquitin-proteasome pathway in muscle atrophy?

2001 • 412 citations

Control of muscle development by dueling HATs and HDACs

2001 • 405 citations

Integrin and Growth Factor Receptor Crosstalk

2001 • 394 citations

Skeletal muscle myostatin mRNA expression is fiber-type specific and increases during hindlimb unloading

1999 • 363 citations

Patterns of gene expression in atrophying skeletal muscles: response to food deprivation

2002 • 342 citations

Role of calpain in skeletal-muscle protein degradation

1998 • 333 citations

Spherical reflector as an electromagnetic-missile launcher

1990 • 310 citations

Contribution of satellite cells to IGF‐I induced hypertrophy of skeletal muscle

1999 • 287 citations

Coordinate activation of lysosomal, Ca2+-activated and ATP-ubiquitin-dependent proteinases in the unweighted rat soleus muscle

1996 • 278 citations

Activation of an alternative <scp>NF‐ΚB</scp> pathway in skeletal muscle during disuse atrophy

2002 • 275 citations

Dynamics of nuclei of muscle fibers and connective tissue cells in normal and denervated rat muscles

2000 • 236 citations

Time course of changes in markers of myogenesis in overloaded rat skeletal muscles

1999 • 235 citations

Structural and functional responses to prolonged hindlimb suspension in rat muscle

1987 • 234 citations

Modulation of myostatin expression during modified muscle use

2000 • 228 citations

Expression of a calpastatin transgene slows muscle wasting and obviates changes in myosin isoform expression during murine muscle disuse

2002 • 216 citations

SV2 modulates the size of the readily releasable pool of secretory vesicles

2001 • 204 citations

Space shuttle flight (STS‐90) enhances degradation of rat myosin heavy chain in association with activation of ubiquitin‐proteasome pathway

2001 • 187 citations

IGF-binding protein-5: flexible player in the IGF system and effector on its own

2002 • 184 citations

An E-box within the MHC IIB gene is bound by MyoD and is required for gene expression in fast muscle

1999 • 176 citations

Prediction of amorphous phase stability in the metal–silicon systems

2001 • 173 citations

Hindlimb suspension suppresses muscle growth and satellite cell proliferation

1989 • 172 citations

Inference from Clustering with Application to Gene-Expression Microarrays

2002 • 162 citations

Mechanism of oxidative stress in skeletal muscle atrophied by immobilization

1993 • 162 citations

Physical and Functional Interactions among AP-2 Transcription Factors, p300/CREB-binding Protein, and CITED2

2003 • 146 citations

The bHLH Gene Hes1 Regulates Differentiation of Multiple Cell Types

2000 • 142 citations

Iron accumulation in aging: modulation by dietary restriction

1998 • 138 citations

Insulin-like Growth Factor-binding Protein 5 (IGFBP-5) Interacts with a Four and a Half LIM Protein 2 (FHL2)

2002 • 135 citations

A Human Putative Lymphocyte G₀/G₁Switch Gene Containing a CpG-Rich Island Encodes a Small Basic Protein with the Potential to Be Phosphorylated

1991 • 134 citations

Trace element movement and oxidative stress in skeletal muscle atrophied by immobilization

1992 • 109 citations

Patterns of global gene expression in rat skeletal muscle during unloading and low-intensity ambulatory activity

2003 • 108 citations

Intramuscular Extracellular Matrix: Complex Environment of Muscle Cells

2002 • 101 citations

Different mechanisms of increased proteolysis in atrophy induced by denervation or unweighting of rat soleus muscle

1990 • 97 citations

Prolonged unloading of rat soleus muscle causes distinct adaptations of the gene profile

2002 • 95 citations

A variable fold‐change threshold determines significance for expression microarrays

2002 • 94 citations

Characterization of control and immobilized skeletal muscle: an overview from genetic engineering

2001 • 91 citations

Serine proteases of the complement system

2000 • 91 citations

Increased myogenic repressor Id mRNA and protein levels in hindlimb muscles of aged rats

2002 • 85 citations

Multiple WW Domains, but Not the C2 Domain, Are Required for Inhibition of the Epithelial Na+ Channel by Human Nedd4

2001 • 84 citations

DETERMINING SIGNIFICANT FOLD DIFFERENCES IN GENE EXPRESSION ANALYSIS

2000 • 80 citations

In vivo analysis of the myosin heavy chain IIB promoter region

1998 • 75 citations

Decreased polysomal HSP-70 may slow polypeptide elongation during skeletal muscle atrophy

1995 • 73 citations

Hindlimb unloading induces a collagen isoform shift in the soleus muscle of the rat

2001 • 72 citations

Content and localization of myostatin in mouse skeletal muscles during aging, mechanical unloading and reloading.

2001 • 71 citations

Acyl-CoA-binding Protein Is a Potent m-Calpain Activator

2000 • 69 citations

Insulin Induction of SOCS-2 and SOCS-3 mRNA Expression in C2C12 Skeletal Muscle Cells Is Mediated by Stat5*

2001 • 69 citations

Energy metabolism pathways in rat muscle under conditions of simulated microgravity

2002 • 68 citations

Increased antioxidant capacity does not attenuate muscle atrophy caused by unweighting

2002 • 68 citations

Acute effects of hindlimb unweighting on satellite cells of growing skeletal muscle

1994 • 66 citations

A novel developmentally regulated gene in lung mesenchyme: homology to a tumor-derived trypsin inhibitor

1999 • 58 citations

Id-1 as a possible transcriptional mediator of muscle disuse atrophy.

1994 • 54 citations

Analysis of altered gene expression in rat soleus muscle atrophied by disuse

2001 • 50 citations

Cystatin inhibition of cathepsin B requires dislocation of the proteinase occluding loop. Demonstration by release of loop anchoring through mutation of His110

2000 • 50 citations

Pharmacokinetic/Pharmacodynamic models for corticosteroid receptor down-regulation and glutamine synthetase induction in rat skeletal muscle by a Receptor/Gene-mediated mechanism.

1999 • 48 citations

Skeletal Muscle-Specific Calpain, p94, and Connectin/Titin: Their Physiological Functions and Relationship to Limb-Girdle Muscular Dystrophy Type 2A

2000 • 47 citations

Posttranscriptional regulation of Id1 activity in cardiac muscle. Alternative splicing of novel Id1 transcript permits homodimerization.

1994 • 45 citations

Skeletal muscle IGF-binding protein-3 and -5 expressions are age, muscle, and load dependent

2003 • 45 citations

Glutamine synthetase expression in muscle is regulated by transcriptional and posttranscriptional mechanisms

1999 • 43 citations

Myofibril-bound serine protease and its endogenous inhibitor in mouse: extraction, partial characterization and effect on myofibrils

2002 • 24 citations

Catabolism of cysteine, cystine, cysteinesulfinate, and OTC by isolated perfused rat hindquarter

1993 • 18 citations

Identification of Weight-bearing-responsive Elements in the Skeletal Muscle Sarco(endo)plasmic Reticulum Ca2+ ATPase (SERCA1) Gene

2000 • 14 citations