Evidence for the presence of a protease-activated receptor distinct from the thrombin receptor in human keratinocytes.

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

2012 • 8,865 citations

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

1991 • 2,981 citations

Molecular cloning of a potential proteinase activated receptor.

1994 • 887 citations

cDNA cloning and expression of a hamster α‐thrombin receptor coupled to Ca²⁺ mobilization

1991 • 464 citations

Tethered ligand agonist peptides. Structural requirements for thrombin receptor activation reveal mechanism of proteolytic unmasking of agonist function.

1992 • 291 citations

Inositol 1,3,4,5-tetrakisphosphate and not phosphatidylinositol 3,4-bisphosphate is the probable precursor of inositol 1,3,4-trisphosphate in agonist-stimulated parotid gland

1986 • 283 citations

Intracellular targeting and trafficking of thrombin receptors. A novel mechanism for resensitization of a G protein-coupled receptor.

1994 • 228 citations

Specificity of the thrombin receptor for agonist peptide is defined by its extracellular surface

1994 • 210 citations

Thrombin active site regions required for fibroblast receptor binding and initiation of cell division.

1980 • 186 citations

Molecular cloning of the rat vascular smooth muscle thrombin receptor. Evidence for in vitro regulation by basic fibroblast growth factor.

1992 • 165 citations

Thrombin-induced events in non-platelet cells are mediated by the unique proteolytic mechanism established for the cloned platelet thrombin receptor.

1992 • 146 citations

Changes in the structure and function of the human thrombin receptor during receptor activation, internalization, and recycling.

1994 • 145 citations

Deregulation of hamster fibroblast proliferation by mutated ras oncogenes is not mediated by constitutive activation of phosphoinositide-specific phospholipase C.

1988 • 143 citations

Role of proteolysis in apoptosis: involvement of serine proteases in internucleosomal DNA fragmentation in immature thymocytes

1993 • 109 citations

Protease-activated receptors start a family.

1994 • 90 citations

Proteases stimulate proliferation of human fibroblasts

1977 • 84 citations

alpha-Thrombin-induced early mitogenic signalling events and G0 to S-phase transition of fibroblasts require continual external stimulation.

1985 • 83 citations

Thrombomodulin expression by human keratinocytes. Induction of cofactor activity during epidermal differentiation.

1994 • 72 citations

Agonist-induced Hydrolysis of Phosphoinositides and Formation of 1,2-Diacylglycerol in Adult Human Keratinocytes

1989 • 36 citations

Functional and Immunoreactive Thrombomodulin Expressed by Keratinocytes

1994 • 28 citations

Long‐term effects of thrombin require sustained activation of the functional thrombin receptor

1993 • 14 citations