Production of murine V-human cr1 chimeric anti-tag72 antibody using V region cdna amplified by PCR

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

Chimeric human antibody molecules: mouse antigen-binding domains with human constant region domains.

1984 • 1,002 citations

Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli

1989 • 989 citations

Enhancer-dependent expression of human kappa immunoglobulin genes introduced into mouse pre-B lymphocytes by electroporation.

1984 • 889 citations

Direct Cloning and Sequence Analysis of Enzymatically Amplified Genomic Sequences

1986 • 766 citations

Cloning immunoglobulin variable domains for expression by the polymerase chain reaction.

1989 • 712 citations

Mouse monoclonal IgG3 antibody detecting GD3 ganglioside: a phase I trial in patients with malignant melanoma.

1985 • 566 citations

Production of functional chimaeric mouse/human antibody

1984 • 539 citations

Mouse/human chimeric monoclonal antibody in man: kinetics and immune response.

1989 • 526 citations

Distribution of oncofetal antigen tumor-associated glycoprotein-72 defined by monoclonal antibody B72.3.

1986 • 456 citations

Human immune response to multiple injections of murine monoclonal IgG.

1985 • 425 citations

Identification and purification of a human lymphoid-specific octamer-binding protein (OTF-2) that activates transcription of an immunoglobulin promoter in vitro

1987 • 386 citations

Generation of cDNA Probes Directed by Amino Acid Sequence: Cloning of Urate Oxidase

1988 • 325 citations

A monoclonal antibody (B72.3) defines patterns of distribution of a novel tumor‐associated antigen in human mammary carcinoma cell populations

1982 • 324 citations

Chimeric mouse-human IgG1 antibody that can mediate lysis of cancer cells.

1987 • 204 citations

Biological activity of human-mouse IgG1, IgG2, IgG3, and IgG4 chimeric monoclonal antibodies with antitumor specificity.

1988 • 202 citations

Differential reactivity of monoclonal antibodies with human colon adenocarcinomas and adenomas

1983 • 196 citations

Complementation of intracavitary and intravenous administration of a monoclonal antibody (B72.3) in patients with carcinoma.

1987 • 166 citations

Chimeric antibody with human constant regions and mouse variable regions directed against carcinoma-associated antigen 17-1A.

1987 • 137 citations

Tumor-Associated Glycoprotein (TAG-72) in Ovarian Carcinomas Defined by Monoclonal Antibody 872.3

1986 • 137 citations

Quantitative and qualitative aspects of radiolocalization in colon cancer patients of intravenously administered MAb B72.3

1987 • 125 citations

Quantitative analyses of selective radiolabeled monoclonal antibody localization in metastatic lesions of colorectal cancer patients.

1987 • 124 citations

Structural correlates of cross-reactive and individual idiotypic determinants on murine antibodies to alpha-(1 leads to 3) dextran.

1980 • 115 citations

A genetically engineered murine/human chimeric antibody retains specificity for human tumor-associated antigen.

1990 • 111 citations

Characterization and biodistribution of recombinant and recombinant/chimeric constructs of monoclonal antibody B72.3.

1989 • 105 citations

Radioimmunoguided surgery using the monoclonal antibody B72.3 in colorectal tumors

1987 • 103 citations

Expression in COS cells of a mouse—human chimaeric B72.3 antibody

1987 • 100 citations

Biological and Clinical Implications of Lymphocyte Hybridomas: Tumor Therapy with Monoclonal Antibodies

1983 • 91 citations

Radioimmunoscintigraphy of colon cancer with iodine-131-labeled B72.3 monoclonal antibody.

1988 • 91 citations

A genetically engineered murine/human chimeric antibody retains specificity for human tumor-associated antigen.

1986 • 86 citations

Galactan-binding antibodies. Diversity and structure of idiotypes.

1983 • 78 citations

Structural features of human tracheobronchial mucus glycoprotein

1984 • 68 citations

Complementation of anti‐CEA and anti‐TAG‐72 monoclonal antibodies in reactivity to human gastric adenocarcinomas

1987 • 52 citations

Immunoscintigraphy in the follow-up of patients operated on for carcinoma of the sigmoid and rectum

1987 • 44 citations

Monoclonal antibodies to streptococcal group A carbohydrate. I. A dominant idiotypic determinant is located on Vk.

1982 • 43 citations

Intraoperative radioimmunolocalization of colorectal carcinoma with a hand‐held gamma probe and MAb B72.3: Comparison of in vivo gamma probe counts with in vitro MAb radiolocalization

1988 • 40 citations

Peritoneal carcinomatosis: imaging with intraperitoneal injection of I-131-labeled B72.3 monoclonal antibody.

1988 • 39 citations

High Levels of Met-72 Antigen Expression: Correlation With Metastatic Activity of B6 Melanoma Tumor Cell Variants<xref ref-type="fn" rid="FN2">2</xref>

1986 • 33 citations