Production of functional chimaeric mouse/human antibody

Bacteriophages

1959 • 1,937 citations

Derivation of specific antibody‐producing tissue culture and tumor lines by cell fusion

1976 • 1,926 citations

A better cell line for making hybridomas secreting specific antibodies

1978 • 1,649 citations

Transformation of mammalian cells with genes from procaryotes and eucaryotes

1979 • 1,474 citations

Methods in Immunology and Immunochemistry

1967 • 1,145 citations

Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase.

1981 • 1,048 citations

Three-Dimensional Structure of Immunoglobulins

1979 • 692 citations

Cloned human and mouse kappa immunoglobulin constant and J region genes conserve homology in functional segments

1980 • 402 citations

The roles of individual polyoma virus early proteins in oncogenic transformation

1982 • 366 citations

Direct transfer of cloned genes from bacteria to mammalian cells.

1980 • 291 citations

Genetics, Expression, and Function of Idiotypes

1983 • 264 citations

Correlation between segmental flexibility and effector function of antibodies

1984 • 235 citations

Human immunoglobulin heavy chain genes: evolutionary comparisons of Cμ, Cδ and Cγ genes and associated switch sequences

1981 • 205 citations

Mutant immunoglobulin genes have repetitive DNA elements inserted into their intervening sequences.

1982 • 150 citations

High-Frequency Transfer of Cloned Herpes Simplex Virus Type 1 Sequences to Mammalian Cells by Protoplast Fusion

1981 • 133 citations

Functional immunoglobulin M production after transfection of cloned immunoglobulin heavy and light chain genes into lymphoid cells.

1983 • 121 citations

Antigen-induced co-capping of IgM and IgD-like receptors on murine B cells.

1976 • 108 citations

Biological and Clinical Implications of Lymphocyte Hybridomas: Tumor Therapy with Monoclonal Antibodies

1983 • 91 citations

High-frequency transfer of cloned herpes simplex virus type 1 sequences to mammalian cells by protoplast fusion.

1981 • 80 citations

Transfer of a cloned immunoglobulin light-chain gene to mutant hybridoma cells restores specific antibody production

1983 • 78 citations

Switch from hapten-specific immunoglobulin M to immunoglobulin D secretion in a hybrid mouse cell line.

1981 • 78 citations

Mutations affecting the structure and function of immunoglobulin M.

1982 • 69 citations

Methods in immunology and immunochemistry

1978 • 67 citations

Expression of a VHCκ chimaeric protein in mouse myeloma cells

1984 • 57 citations

Inactivation of Bacteriophage T4, of Poly-D-Alanyl Bacteriophage and of Penicilloyl Bacteriophage by Immunospecifically Isolated IgM and IgG Antibodies

1969 • 35 citations

Biochemical genetics of the mouse IgM system

1984 • 2 citations