Serum interleukin-6 and C-reactive protein as a prognostic indicator in hepatocellular carcinoma

Inflammation and cancer

2002 • 14,174 citations

Immunity, Inflammation, and Cancer

2010 • 9,544 citations

Modified RECIST (mRECIST) Assessment for Hepatocellular Carcinoma

2010 • 3,699 citations

NF-κB: linking inflammation and immunity to cancer development and progression

2005 • 2,878 citations

Interleukin-6 and the acute phase response

1990 • 2,740 citations

Distinct Role of Macrophages in Different Tumor Microenvironments

2006 • 2,130 citations

Radical causes of cancer

2003 • 1,611 citations

Interleukin-6 in Biology and Medicine

1993 • 1,398 citations

NF-κB and STAT3 – key players in liver inflammation and cancer

2010 • 1,002 citations

Acute-phase response of human hepatocytes: Regulation of acute-phase protein synthesis by interleukin-6

1990 • 742 citations

Humoral immunity, inflammation and cancer

2007 • 403 citations

The role of cytokines in hepatocellular carcinoma

2006 • 307 citations

Interleukin-6 Protects against Fas-mediated Death by Establishing a Critical Level of Anti-apoptotic Hepatic Proteins FLIP, Bcl-2, and Bcl-xL

2001 • 282 citations

The impact of preoperative serum C‐reactive protein on the prognosis of patients with hepatocellular carcinoma

2005 • 265 citations

Practice guidelines for management of hepatocellular carcinoma 2009

2009 • 251 citations

Interleukin-8 serum levels in patients with hepatocellular carcinoma: correlations with clinicopathological features and prognosis.

2003 • 177 citations

Circulating interleukin-6 as a tumor marker for hepatocellular carcinoma

2007 • 155 citations

Serum Interleukin-10 But Not Interleukin-6 Is Related to Clinical Outcome in Patients With Resectable Hepatocellular Carcinoma

2000 • 143 citations

C-reactive protein and malignancy: clinico-pathological association and therapeutic implication.

2009 • 129 citations

Evaluation of interleukin-6, interleukin-10 and human hepatocyte growth factor as tumor markers for hepatocellular carcinoma

2006 • 116 citations

Interleukin-6 and its soluble receptor in patients with liver cirrhosis and hepatocellular carcinoma

2006 • 115 citations

Serum α-Fetoprotein Response as a Surrogate for Clinical Outcome in Patients Receiving Systemic Therapy for Advanced Hepatocellular Carcinoma

2009 • 104 citations

Serum C‐reactive protein levels predict survival in hepatocellular carcinoma

2007 • 97 citations

Increased intrahepatic messenger RNA expression of interleukins 2, 6, and 8 in human cirrhosis

1994 • 94 citations

Immunohistochemical expression of C-reactive protein in squamous cell carcinoma of the esophagus - significance as a tumor marker

2003 • 88 citations

Human interleukin 6 gene is activated by hepatitis B virus-X protein in human hepatoma cells.

1998 • 76 citations

Circulating IL‐6 and sIL‐6R in Patients with Hepatocellular Carcinoma

2002 • 63 citations

Role of serum interleukin-18 as a prognostic factor in patients with hepatocellular carcinoma

2007 • 63 citations

Possible contribution of circulating interleukin-10 (IL-10) to anti-tumor immunity and prognosis in patients with unresectable hepatocellular carcinoma

2003 • 53 citations

[Role of interleukin 6 in hepatocellular carcinoma].

1996 • 33 citations

Effect of IL-6 overexpression on the metastatic potential of rat hepatocellular carcinoma cells

1998 • 22 citations