Regulation of platelet-derived growth factor receptor expression by cell context overrides regulation by cytokines

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Establishment and characterization of a human acute monocytic leukemia cell line (THP‐1)

1980 • 2,158 citations

TGF-β induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop

1990 • 756 citations

Platelet-derived growth factor promotes smooth muscle migration and intimal thickening in a rat model of balloon angioplasty.

1992 • 681 citations

Two Different Subunits Associate to Create Isoform-Specific Platelet-derived Growth Factor Receptors

1989 • 633 citations

Simultaneous staining of ribonucleic and deoxyribonucleic acids in unfixed cells using acridine orange in a flow cytofluorometric system.

1977 • 413 citations

Activation of cultured rat hepatic lipocytes by Kupffer cell conditioned medium. Direct enhancement of matrix synthesis and stimulation of cell proliferation via induction of platelet-derived growth factor receptors.

1989 • 401 citations

Dimerization of B-type Platelet-derived Growth Factor Receptors Occurs After Ligand Binding and Is Closely Associated with Receptor Kinase Activation

1989 • 366 citations

Platelet-derived growth factor. II. Specific binding to cultured cells.

1982 • 366 citations

Cloning and expression of a cDNA coding for the human platelet-derived growth factor receptor: evidence for more than one receptor class.

1988 • 314 citations

Induction of beta-platelet-derived growth factor receptor in rat hepatic lipocytes during cellular activation in vivo and in culture.

1994 • 300 citations

Platelet-derived growth factor (PDGF) and PDGF receptor are induced in mesangial proliferative nephritis in the rat.

1991 • 293 citations

PARAQUAT POISONING

1976 • 280 citations

INDUCTION OF B-TYPE RECEPTORS FOR PLATELET-DERIVED GROWTH FACTOR IN VASCULAR INFLAMMATION: POSSIBLE IMPLICATIONS FOR DEVELOPMENT OF VASCULAR PROLIFERATIVE LESIONS

1988 • 247 citations

Extracellular matrix organization modulates fibroblast growth and growth factor responsiveness

1989 • 216 citations

Platelet-derived growth factor (PDGF) stimulates PDGF receptor subunit dimerization and intersubunit trans-phosphorylation

1991 • 196 citations

Ligand-induced dimerization of the platelet-derived growth factor receptor

1989 • 190 citations

Integrating with integrins.

1994 • 189 citations

Selective upregulation of platelet-derived growth factor alpha receptors by transforming growth factor beta in scleroderma fibroblasts.

1992 • 181 citations

Modulation of platelet-derived growth factor receptor expression in microvascular endothelial cells during in vitro angiogenesis.

1994 • 152 citations

BrdU—Hoechst flow cytometry: A unique tool for quantitative cell cycle analysis

1988 • 148 citations

Platelet-derived growth factor receptors in the kidney—Upregulated expression in inflammation

1989 • 141 citations

Differential regulation of expression of two platelet-derived growth factor receptor subunits by transforming growth factor-β

1989 • 136 citations

Induction of platelet-derived growth factor receptor expression in smooth muscle cells and fibroblasts upon tissue culturing.

1988 • 135 citations

Developmental patterns of PDGF B-chain, PDGF-receptor, and α-actin expression in human glomerulogenesis

1992 • 131 citations

Elevated Levels of PDGF α Receptors in Keloid Fibroblasts Contribute to an Enhanced Response to PDGF

1994 • 126 citations

Increased expression of platelet‐derived growth factor type b receptors in the skin of patients with systemic sclerosis

1990 • 115 citations

Decreased level of PDGF-stimulated receptor autophosphorylation by fibroblasts in mechanically relaxed collagen matrices

1993 • 105 citations

Synthesis, phosphorylation, and degradation of multiple forms of the platelet-derived growth factor receptor studied using a monoclonal antibody.

1987 • 102 citations

Polypeptides on human B lymphocytes associated with cell activation

1986 • 98 citations

Expression of platelet-derived growth factor and its receptors in proliferative disorders of fibroblastic origin.

1992 • 94 citations

Basic fibroblast growth factor modulates the mitogenic potency of the platelet-derived growth factor (PDGF) isoforms by specific upregulation of the PDGF alpha receptor in vascular smooth muscle cells.

1992 • 71 citations

Persistence of the mitogenic response to platelet-derived growth factor (competence) does not reflect a long-term interaction between the growth factor and the target cell.

1983 • 70 citations

Interactions between autoimmunity and molecular and cell biology. Bridges between clinical and basic sciences.

1989 • 60 citations

Platelet-derived growth factor receptor (beta-subunit) immunoreactivity in soft tissue tumors.

1992 • 58 citations

Increased Dermal Expression of Platelet-Derived Growth Factor Receptors in Growth-Activated Skin Wounds and Psoriasis

1990 • 56 citations

Platelet-derived growth factor: A potentially important cytokine in glomerular disease

1992 • 54 citations

Spatial organization of the extracellular matrix modulates the expression of PDGF-receptor subunits in mesangial cells

1993 • 43 citations

Density‐dependent inhibitory effect of transforming growth factor‐β on human fibroblasts involves the down‐regulation of platelet‐derived growth factor α‐receptors

1993 • 36 citations

Expression of platelet-derived growth factor-beta receptors on human fibroblasts. Regulation by recombinant platelet-derived growth factor-BB, IL-1, and tumor necrosis factor-alpha.

1992 • 30 citations

Differential Regulation of the Genes Encoding Platelet-derived Growth Factor Receptor and its Ligand in Rat Lung during Microvascular and Alveolar Wall Remodeling in Hyperoxia

1992 • 26 citations