Differential Regulation of the Genes Encoding Platelet-derived Growth Factor Receptor and its Ligand in Rat Lung during Microvascular and Alveolar Wall Remodeling in Hyperoxia

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

1986 • 1,244 citations

A Heparin-Binding Growth Factor Secreted by Macrophage-Like Cells That Is Related to EGF

1991 • 1,135 citations

pl Bl5: A cDNA Clone of the Rat mRNA Encoding Cyclophilin

1988 • 1,039 citations

PLATELET-DERIVED GROWTH FACTOR

1989 • 967 citations

Platelet-derived growth factor in chemotactic for fibroblasts.

1982 • 744 citations

A significant part of macrophage-derived growth factor consists of at least two forms of PDGF

1985 • 719 citations

Interleukin-1 Mitogenic Activity for Fibroblasts and Smooth Muscle Cells Is Due to PDGF-AA

1989 • 648 citations

Two Different Subunits Associate to Create Isoform-Specific Platelet-derived Growth Factor Receptors

1989 • 633 citations

Isolation of a Novel Receptor cDNA Establishes the Existence of Two PDGF Receptor Genes

1989 • 610 citations

Two Classes of PDGF Receptor Eecognize Different Isoforms of PDGF

1988 • 603 citations

Localization of PDGF-B Protein in Macrophages in All Phases of Atherogenesis

1990 • 584 citations

Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor beta: a proposed model for indirect mitogenesis involving autocrine activity.

1986 • 541 citations

Cultured endothelial cells produce a platelet-derived growth factor-like protein

1983 • 507 citations

PDGF ligand and receptor gene expression during repair of arterial injury.

1990 • 431 citations

Activated human monocytes express the c-sis proto-oncogene and release a mediator showing PDGF-like activity

1986 • 380 citations

Platelet‐derived growth factor is a chemoattractant for vascular smooth muscle cells

1982 • 340 citations

Possible positive autocrine feedback in the prereplicative phase of human fibroblasts

1987 • 234 citations

Purification of PDGF-AB and PDGF-BB from human platelet extracts and identification of all three PDGF dimers in human platelets

1990 • 226 citations

Expression of the sis gene by endothelial cells in culture and in vivo.

1984 • 221 citations

Injury induces in vivo expression of platelet-derived growth factor (PDGF) and PDGF receptor mRNAs in skin epithelial cells and PDGF mRNA in connective tissue fibroblasts.

1991 • 220 citations

Sera and conditioned media contain different isoforms of platelet-derived growth factor (PDGF) which bind to different classes of PDGF receptor

1989 • 216 citations

Selective expression of PDGF A and its receptor during early mouse embryogenesis

1990 • 215 citations

Ligand-induced dimerization of the platelet-derived growth factor receptor

1989 • 190 citations

Human microvascular endothelial cells express receptors for platelet-derived growth factor.

1991 • 154 citations

Transcriptional regulation of the A and B chain genes of platelet-derived growth factor in microvascular endothelial cells.

1988 • 138 citations

Pulmonary artery remodeling and pulmonary hypertension after exposure to hyperoxia for 7 days. A morphometric and hemodynamic study.

1984 • 103 citations

A human glioma cell line secretes three structurally and functionally different dimeric forms of platelet‐derived growth factor

1988 • 88 citations

Isolation and characterization of the alpha platelet-derived growth factor receptor from rat olfactory epithelium.

1990 • 69 citations

Methotrexate-induced Asthma

1991 • 61 citations

Ultrastructural analysis of contractile cell development in lung microvessels in hyperoxic pulmonary hypertension. Fibroblasts and intermediate cells selectively reorganize nonmuscular segments.

1992 • 47 citations

Expression of PDGF α- and β-receptors in Rat Arterial Smooth Muscle Cells is Phenotype and Growth State Dependent

1990 • 44 citations

Oxygen toxicity and restructuring of pulmonary arteries--a morphometric study. The response to 4 weeks' exposure to hyperoxia and return to breathing air.

1985 • 43 citations

The Platelet-Derived Growth Factor Receptor

1985 • 40 citations

Increased Expression of PDGF-B (c-sis) mRNA in Rat Lung Precedes DNA Synthesis and Tissue Repair during Chronic Hyperoxia

1989 • 40 citations

Platelet-derived growth factor production by human umbilical vein endothelial cells is regulated by basic fibroblast growth factor

1989 • 37 citations

Lung Vascular Cell Proliferation in Hyperoxic Pulmonary Hypertension and on Return to Air: [³H]Thymidine Pulse-labeling of Intimal, Medial, and Adventitial Cells in Microvessels and at the Hilum

1989 • 27 citations

Injury and remodeling of pulmonary veins by high oxygen. A morphometric study.

1989 • 25 citations