Mutations at Critical N-Glycosylation Sites Reduce Tyrosinase Activity by Altering Folding and Quality Control

ASSEMBLY OF ASPARAGINE-LINKED OLIGOSACCHARIDES

1985 • 4,790 citations

Glucose trimming and reglucosylation determine glycoprotein association with calnexin in the endoplasmic reticulum

1995 • 544 citations

Recognition of the oligosaccharide and protein moieties of glycoproteins by the UDP-Glc:glycoprotein glucosyltransferase

1992 • 313 citations

Functional analysis of alternatively spliced tyrosinase gene transcripts.

1988 • 275 citations

The Number and Location of Glycans on Influenza Hemagglutinin Determine Folding and Association with Calnexin and Calreticulin

1997 • 258 citations

Tyrosinases from two different loci are expressed by normal and by transformed melanocytes.

1991 • 233 citations

[22] Mammalian monophenol monooxygenase (tyrosinase): Purification, properties, and reactions catalyzed

1987 • 217 citations

Conformation-Independent Binding of Monoglucosylated Ribonuclease B to Calnexin

1997 • 195 citations

Glucosylation of glycoproteins by mammalian, plant, fungal, and trypanosomatid protozoa microsomal membranes

1989 • 155 citations

N-linked oligosaccharides are necessary and sufficient for association of glycosylated forms of bovine RNase with calnexin and calreticulin.

1996 • 149 citations

Melanin biosynthesis patterns following hormonal stimulation.

1993 • 117 citations

Detection of Mutations in the Tyrosinase Gene in a Patient with Type IA Oculocutaneous Albinism

1990 • 92 citations

Transient glucosylation of protein-bound Man9GlcNAc2, Man8GlcNAc2, and Man7GlcNAc2 in calf thyroid cells. A possible recognition signal in the processing of glycoproteins.

1983 • 84 citations

Tyrosinase Folding and Copper Loading in Vivo: A Crucial Role for Calnexin and α-Glucosidase II

1999 • 84 citations

Inhibition of N-Glycan Processing in B16 Melanoma Cells Results in Inactivation of Tyrosinase but Does Not Prevent Its Transport to the Melanosome

1997 • 81 citations

Promotion of Tyrosinase Folding in Cos 7 Cells by Calnexin

1999 • 69 citations

Purification of hamster melanoma tyrosinases and structural studies of their asparagine-linked sugar chains

1984 • 66 citations

A misfolded protein conformation is not a sufficient condition for invivo glucosylation by the UDP-Glc:glycoprotein glucosyltransferase

1998 • 45 citations

Leaving no element of doubt: analysis of proteins using microPIXE

1999 • 41 citations

Albinism

1989 • 27 citations

Molecular analyses of a tyrosinase-negative albino family.

1993 • 21 citations