Tyrosinases from two different loci are expressed by normal and by transformed melanocytes.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Biology of the Laboratory Mouse

1967 • 1,382 citations

A line of non‐tumorigenic mouse melanocytes, syngeneic with the B16 melanoma and requiring a tumour promoter for growth

1987 • 475 citations

Isolation and sequence of a cDNA clone for human tyrosinase that maps at the mouse c-albino locus.

1987 • 448 citations

Mammalian tyrosinase—The critical regulatory control point in melanocyte pigmentation

1987 • 439 citations

Functional analysis of alternatively spliced tyrosinase gene transcripts.

1988 • 275 citations

A cDNA encoding tyrosinase-related protein maps to the brown locus in mouse.

1988 • 247 citations

New regulators of melanin biosynthesis and the autodestruction of melanoma cells

1980 • 244 citations

Cloning and expression of cDNA encoding mouse tyrosinase

1986 • 241 citations

Analysis of Mammalian Pigmentation at the Molecular Level

1989 • 238 citations

Genetic control of morphogenetic and biochemical differentiation: Lethal albino deletions in the mouse

1979 • 221 citations

[22] Mammalian monophenol monooxygenase (tyrosinase): Purification, properties, and reactions catalyzed

1987 • 217 citations

Mammalian tyrosinase. A comparison of tyrosine hydroxylation and melanin formation

1976 • 208 citations

The melanoma antigen gp75 is the human homologue of the mouse b (brown) locus gene product.

1990 • 203 citations

Induction of pigmentation in mouse fibroblasts by expression of human tyrosinase cDNA.

1989 • 186 citations

Multiple transcripts of the mouse tyrosinase gene are generated by alternative splicing.

1988 • 184 citations

Regulation of mammalian melanogenesis I: partial purification and characterization of a dopachrome converting factor: dopachrome tautomerase

1990 • 175 citations

The molecular basis of brown, an old mouse mutation, and of an induced revertant to wild type.

1990 • 162 citations

Melanocyte-stimulating hormone promotes activation of pre-existing tyrosinase molecules in Cloudman S91 melanoma cells

1975 • 157 citations

Sequence analysis of mouse tyrosinase cDNA and the effect of melanotropin on its gene expression

1988 • 156 citations

Murine and human b locus pigmentation genes encode a glycoprotein (gp75) with catalase activity.

1990 • 146 citations

Cloned mouse melanocyte lines carrying the germline mutations albino and brown: complementation in culture

1989 • 139 citations

Mammalian tyrosinase: biosynthesis, processing, and modulation by melanocyte-stimulating hormone.

1988 • 135 citations

Dopachrome Oxidoreductase: A New Enzyme in the Pigment Pathway

1984 • 133 citations

Alpha-melanocyte-stimulating hormone regulation of tyrosinase in Cloudman S-91 mouse melanoma cell cultures.

1987 • 123 citations

Cloning and sequencing of mouse tyrosinase cDNA.

1987 • 119 citations

Melanin production in cultured albino melanocytes transfected with mouse tyrosinase cDNA.

1989 • 111 citations

A point mutation in the tyrosinase gene of BALB/c albino mouse causing the cysteine → serine substitution at position 85

1990 • 110 citations

Specific Identification of an Authentic Clone for Mammalian Tyrosinase

1989 • 106 citations

Coenzymes and Cofactors

2015 • 106 citations

Nucleotide sequence of the cDNA encoding human tyrosinase-related protein

1990 • 103 citations

Molecular basis for the heterogeneity of human tyrosinase.

1988 • 98 citations

Effect of genic substitution on the incorporation of tyrosine into the melanin of mouse skin

1962 • 97 citations

Function of dopachrome oxidoreductase and metal ions in dopachrome conversion in the eumelanin pathway

1988 • 96 citations

Dopachrome conversion factor functions as an isomerase

1990 • 96 citations

Tyrosinases of murine melanocytes with mutations at the albino locus.

1988 • 88 citations

Tyrosinase isozyme heterogeneity in differentiating B16/C3 melanoma.

1986 • 83 citations

Normal murine melanocytes in culture

1987 • 82 citations

Structural modifications in biosynthetic melanins induced by metal ions

1988 • 82 citations

Mammalian tyrosinase: Isozymic forms of the enzyme

1981 • 71 citations

Hairbulb tyrosinase activity in oculocutaneous albinism

1976 • 67 citations

Mammalian tyrosinase. Structural and functional interrelationship of isozymes

1978 • 67 citations

Purification of hamster melanoma tyrosinases and structural studies of their asparagine-linked sugar chains

1984 • 66 citations

Anti-T4-Tyrosinase Monoclonal Antibodies—Specific Markers for Pigmented Melanocytes

1985 • 65 citations

Regulation of tyrosinase mRNA levels in mouse melanoma cell clones by melanocyte-stimulating hormone and cyclic AMP

1989 • 61 citations

Tyrosinase Activity in Subcellular Fractions of Black and Albino Mice

1973 • 60 citations

Hormonal effects of vitamin D₃ on epidermal melanocytes

1988 • 55 citations

Tyrosinase subcellular distribution and kinetic parameters in wild type and c‐locus mutant C57BL/6J mice

1981 • 54 citations

Studies on the Cloudman melanoma cell line as a model for the action of MSH.

1985 • 50 citations

Regulation of mammalian melanogenesis by tyrosinase inhibition

1989 • 44 citations

Murine melanoma-specific tumor rejection activity elicited by a purified, melanoma-associated antigen.

1986 • 42 citations

Isolation and characterization of variant cDNAs encoding mouse tyrosinase

1989 • 34 citations

γ-Glutamyl Transpeptidase, Tyrosinase, and 5-S-Cysteinyldopa Production in Melanoma Cells

1983 • 33 citations

Tyrosinase in the skin of albino hamsters and mice

1974 • 33 citations

Expression of melanocyte stimulating hormone receptors correlates with mammalian pigmentation, and can be modulated by interferons

1988 • 32 citations

Activation of mammalian tyrosinase by ferrous ions

1990 • 26 citations

Comparison of tyrosinase levels in amelanotic and melanotic melanoma cell cultures by a competitive enzyme‐linked immunoadsorbent assay and by immunotitration analysis

1988 • 24 citations

Conversion of particulate tyrosinase to soluble form and to desialylated tyrosinase in human malignant melanoma

1977 • 24 citations

Expression of tyrosinase gene in amelanotic mutant mice

1988 • 18 citations

Half-lives of tyrosinase isozymes from Harding-Passey mouse melanoma

1988 • 13 citations

Genetics and biology of mouse melanocytes: Mutation, migration and interaction

1985 • 10 citations