Inflammatory Cytokines Interact to Modulate Extracellular Matrix and Astrocytic Support of Neurite Outgrowth

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

1994 • 5,932 citations

Signal transduction by receptors with tyrosine kinase activity

1990 • 5,528 citations

Oncogenes and signal transduction

1991 • 2,816 citations

Growth of a rat neuroblastoma cell line in serum-free supplemented medium.

1979 • 2,285 citations

Histologie du système nerveux de l'homme & des vertébrés

1909 • 2,282 citations

Axonal Elongation into Peripheral Nervous System "Bridges" After Central Nervous System Injury in Adult Rats

1981 • 1,679 citations

Reduction of neurite outgrowth in a model of glial scarring following CNS injury is correlated with the expression of inhibitory molecules on reactive astrocytes

1991 • 1,171 citations

Tenascin: an extracellular matrix protein involved in tissue interactions during fetal development and oncogenesis

1986 • 989 citations

Interleukin-1 Stimulation of Astroglial Proliferation After Brain Injury

1985 • 855 citations

Fading of immunofluorescence during microscopy: a study of the phenomenon and its remedy

1982 • 822 citations

Cytokines in inflammatory brain lesions: helpful and harmful

1996 • 727 citations

Histologie du Système Nerveux de Lʼhomme et des Vertébrés

1998 • 704 citations

Neurite extension by peripheral and central nervous system neurons in response to substratum-bound fibronectin and laminin

1983 • 672 citations

Inflammatory cytokines within the central nervous system: sources, function, and mechanism of action

1992 • 614 citations

Interleukin-1 injected into mammalian brain stimulates astrogliosis and neovascularization

1988 • 587 citations

Proliferation of astrocytes in vitro in response to cytokines. A primary role for tumor necrosis factor.

1990 • 548 citations

Molecular mechanisms of angiogenesis: fibroblast growth factor signal transduction

1995 • 461 citations

Cytokines, inflammation, and brain injury: role of tumor necrosis factor-alpha.

1994 • 421 citations

J1/tenascin is a repulsive substrate for central nervous system neurons

1990 • 380 citations

Inhibition of neurite outgrowth on astroglial scars in vitro

1990 • 374 citations

The glial scar: its bearing on axonal elongation and transplantation approaches to CNS repair.

1988 • 362 citations

Reactive astrogliosis in the neonatal mouse brain and its modulation by cytokines

1994 • 343 citations

Effects of Transforming Growth Factor β₁, on Scar Production in the Injured Central Nervous System of the Rat

1994 • 302 citations

Enhanced expression of the developmentally regulated extracellular matrix molecule tenascin following adult brain injury.

1992 • 297 citations

A time course for the focal elevation of synthesis of basic fibroblast growth factor and one of its high-affinity receptors (flg) following a localized cortical brain injury

1992 • 289 citations

Growth of purified astrocytes in a chemically defined medium.

1981 • 268 citations

Gamma-interferon promotes proliferation of adult human astrocytes in vitro and reactive gliosis in the adult mouse brain in vivo.

1991 • 217 citations

Quantitative studies on proliferative changes of reactive astrocytes in mouse cerebral cortex

1988 • 163 citations

Differential effects of gamma-interferon on collagen and fibronectin gene expression.

1987 • 156 citations

Astrogliosis in the Neonatal and Adult Murine Brain Post-Trauma: Elevation of Inflammatory Cytokines and the Lack of Requirement for Endogenous Interferon-γ

1997 • 151 citations

Cross talk between the immune system and the nervous system in response to injury: implications for regeneration

1994 • 149 citations

Amoeboid and ramified microglia: Their interrelationship and response to brain injury

1992 • 123 citations

Effects of transforming growth factor‐β1 on the extracellular matrix and cytoskeleton of cultured astrocytes

1993 • 97 citations

Increased Basic Fibroblast Growth Factor Expression Following Contusive Spinal Cord Injury

1996 • 88 citations

Differential proliferative response of human and mouse astrocytes to gamma‐interferon

1992 • 84 citations

Regulation of Astrocytic Tenascin by Basic Fibroblast Growth Factor

1993 • 81 citations

Chondroitin Sulfate Proteoglycan and Tenascin in the Wounded Adult Mouse NeostriatumIn Vitro: Dopamine Neuron Attachment and Process Outgrowth

1996 • 77 citations

Alterations in Fibroblast Growth Factor Receptor Expression Following Brain Injury

1996 • 72 citations

Cytokine‐induced changes in the ability of astrocytes to support migration of oligodendrocyte precursors and axon growth

1998 • 68 citations

Basic fibroblast growth factor regulates the ability of astrocytes to support hypothalamic neuronal survival in vitro

1991 • 63 citations

Relationship between injury-induced astrogliosis, laminin expression and axonal sprouting in the adult rat brain

1994 • 53 citations

Correlation Between Fibroblast Growth Factor Expression and Cell Proliferation in Experimental Brain Infarct: Studied with Proliferating Cell Nuclear Antigen Immunohistochemistry

1994 • 52 citations

Separate blood and brain origins of proliferating cells during gliosis in adult brains

1990 • 50 citations

Long and Short Splice Variants of Human Tenascin Differentially Regulate Neurite Outgrowth

1997 • 49 citations

Repair of the mammalian spinal cord

1983 • 46 citations

MAP kinase cascade in astrocytes

1994 • 41 citations

Selective labeling of embryonic neurons cultured on astrocyte monolayers with 5(6)-carboxyfluorescein diacetate (CFDA)

1994 • 38 citations

Intralesion Injection of Basic Fibroblast Growth Factor Alters Glial Reactivity to Neural Trauma

1994 • 32 citations

Suramin disrupts the gliotic response following a stab wound injury to the adult rat brain.

1998 • 26 citations

Cell types and cell-substrate interactions in serum-free dissociated cultures of rat hypothalamus

1987 • 21 citations