Gamma-interferon promotes proliferation of adult human astrocytes in vitro and reactive gliosis in the adult mouse brain in vivo.

INTERFERONS AND THEIR ACTIONS

1987 • 1,838 citations

Localization of the glial fibrillary acidic protein in astrocytes by immunofluorescence

1972 • 1,456 citations

Characterization of ameboid microglia isolated from developing mammalian brain

1986 • 1,287 citations

Interleukin-1 Stimulation of Astroglial Proliferation After Brain Injury

1985 • 855 citations

Proliferation of astrocytes in vitro in response to cytokines. A primary role for tumor necrosis factor.

1990 • 548 citations

The role of mononuclear phagocytes in wound healing after traumatic injury to adult mammalian brain

1989 • 504 citations

HLA class II induction in human islet cells by interferon-γ plus tumour necrosis factor or lymphotoxin

1987 • 451 citations

Glia are a unique substrate for the in vitro growth of central nervous system neurons

1984 • 425 citations

Multiple Sclerosis: Distribution of T Cell Subsets Within Active Chronic Lesions

1983 • 417 citations

Fibrillary astrocytes proliferate in response to brain injury

1979 • 399 citations

Injury-induced neuronotrophic activity in adult rat brain: correlation with survival of delayed implants in the wound cavity

1983 • 389 citations

Adult rat brain astrocytes support survival of both NGF-dependent and NGF-insensitive neurones

1979 • 378 citations

Phenotype of the accessory cell necessary for mitogen-stimulated T and B cell responses in human peripheral blood: delineation by its sensitivity to the lysosomotropic agent, L-leucine methyl ester.

1983 • 353 citations

Enhancement by Interferon of the Specific Cytotoxicity of Sensitized Lymphocytes

1972 • 308 citations

Deposition of Scar Tissue in the Central Nervous System

1983 • 285 citations

On the presence of Ia-positive endothelial cells and astrocytes in multiple sclerosis lesions and its relevance to antigen presentation

1985 • 241 citations

Transplants of purified astrocytes promote behavioral recovery after frontal cortex ablation

1986 • 208 citations

Neuroglia: Gliosis and Focal Epilepsy

1970 • 206 citations

Characterization of the origins of astrocyte response to injury using the dopaminergic neurotoxicant, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1990 • 150 citations

Radioautographic evidence for slow astrocyte turnover and modest oligodendrocyte production in the corpus callosum of adult mice infused with3H-thymidine

1988 • 133 citations

Interferon gamma and interleukin 2 synergize to induce selective monokine expression in murine peritoneal macrophages.

1990 • 129 citations

Human astrocytes proliferate in response to tumor necrosis factor alpha

1990 • 124 citations

Proliferation of Astroglia and Oligodendroglia in Response to Human T Cell-Derived Factors

1984 • 113 citations

Differences between adult and neonatal rats in their astroglial response to spinal injury

1984 • 110 citations

Coexpression of granulocyte-macrophage colony-stimulating factor, gamma interferon, and interleukins 3 and 4 is random in murine alloreactive T-lymphocyte clones.

1988 • 106 citations

Immunohistochemical studies of adult human glial cells

1989 • 89 citations

The nature of inflammatory components during demyelination in multiple sclerosis

1988 • 85 citations

A new double labelling immunofluorescence technique for the determination of proliferation of human astrocytes in culture

1987 • 81 citations

In vitro stimulation of glia cells by a lymphocyteproduced factor

1980 • 79 citations

Chapter 45 Transplantation of immature and mature astrocytes and their effect on scar formation in the lesioned central nervous system

1988 • 76 citations

Growth factors for human glial cells in culture

1988 • 70 citations

EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS

1970 • 60 citations

Phorbol ester enhances morphological differentiation of oligodendrocytes in culture

1988 • 58 citations

Transplantation of human sympathetic neurons and adrenal chromaffin cells into parkinsonian monkeys: no reversal of clinical symptoms

1989 • 51 citations

Immunofluorescence studies of the monocytes in the injured rat brain

1981 • 48 citations

Anti-proliferative effect of IFN-gamma in immune regulation. IV. Murine CTL clones produce IL-3 and GM-CSF, the activity of which is masked by the inhibitory action of secreted IFN-gamma.

1990 • 47 citations

Protection against experimental allergic neuritis with silica quartz dust

1982 • 47 citations

Interferons in cell growth and development

1989 • 44 citations

Proteolysis is a critical step in the physiological stop pathway: mechanisms involved in the blockade of axonal regeneration by mammalian astrocytes

1990 • 38 citations

Astroglial contribution in human temporal lobe epilepsy: K+ activation of Na+, K+-ATPase in Bulk isolated glial cells and synaptosomes

1986 • 33 citations

Morphologic heterogeneity of human adult astrocytes in culture: Correlation with HLA‐DR expression

1990 • 30 citations

Dividing and newly produced cells in the corpus callosum of adult mouse cerebrum as detected by light microscopic radioautography.

1983 • 30 citations

Human B cell growth factor enhances proliferation and glial fibrillary acidic protein gene expression in rat astrocytes

1989 • 28 citations

[3H]Thymidine labeling of astrocytes in experimental allergic encephalomyelitis

1987 • 24 citations

Differential responses of CD4+CD45RA+ and CD4+CD29+ subsets to activated CD8+ cells: Enhanced stimulation of the CD4+CD45RA+ subset by cells from patients with multiple sclerosis

1991 • 6 citations