Membrane-mediated structural transitions at the cytoplasmic face during integrin activation

NMRPipe: A multidimensional spectral processing system based on UNIX pipes

1995 • 15,623 citations

Integrins

2002 • 8,127 citations

Integrin Signaling

1999 • 3,705 citations

Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation

2003 • 1,168 citations

Global Conformational Rearrangements in Integrin Extracellular Domains in Outside-In and Inside-Out Signaling

2002 • 1,134 citations

A Transmembrane Helix Dimer: Structure and Implications

1997 • 949 citations

Bidirectional Transmembrane Signaling by Cytoplasmic Domain Separation in Integrins

2003 • 784 citations

The Talin Head Domain Binds to Integrin β Subunit Cytoplasmic Tails and Regulates Integrin Activation

1999 • 697 citations

A common sense approach to peak picking in two-, three-, and four-dimensional spectra using automatic computer analysis of contour diagrams

1991 • 682 citations

Integrin cytoplasmic domains mediate inside-out signal transduction

1994 • 682 citations

Breaking the Integrin Hinge

1996 • 567 citations

Integrin cytoplasmic domain-binding proteins

2000 • 560 citations

A Structural Mechanism of Integrin αIIbβ3 “Inside-Out” Activation as Regulated by Its Cytoplasmic Face

2002 • 511 citations

Structural Determinants of Integrin Recognition by Talin

2003 • 505 citations

Transmembrane signaling in bacterial chemoreceptors

2001 • 431 citations

The Phosphotyrosine Binding-like Domain of Talin Activates Integrins

2002 • 400 citations

Modulation of the Affinity of Integrin α _IIb β ₃ (GPIIb-IIIa) by the Cytoplasmic Domain of α _IIb

1991 • 322 citations

Integrin activation takes shape

2002 • 299 citations

Activation of Integrin αIIbß3 by Modulation of Transmembrane Helix Associations

2003 • 285 citations

Determining the structures of large proteins and protein complexes by NMR

1998 • 265 citations

A Piston Model for Transmembrane Signaling of the Aspartate Receptor

1999 • 265 citations

C-terminal opening mimics 'inside-out' activation of integrin alpha5beta1.

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NMR spectroscopy: a multifaceted approach to macromolecular structure

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[18] Methods to study membrane protein structure in solution

1994 • 183 citations

Association of the Membrane Proximal Regions of the α and β Subunit Cytoplasmic Domains Constrains an Integrin in the Inactive State

2001 • 163 citations

Three-dimensional model of the human platelet integrin α _IIb β ₃ based on electron cryomicroscopy and x-ray crystallography

2002 • 154 citations

A structural basis for integrin activation by the cytoplasmic tail of the α _IIb -subunit

2000 • 136 citations

Integrin tyrosine phosphorylation in platelet signaling

2001 • 101 citations

Solution structures of the cytoplasmic tail complex from platelet integrin αIIb- and β3-subunits

2002 • 99 citations

Determination of the Border between the Transmembrane and Cytoplasmic Domains of Human Integrin Subunits

1999 • 85 citations

Domain-Specific Interactions of Talin with the Membrane-Proximal Region of the Integrin β3 Subunit

2003 • 79 citations

A Conserved Sequence Motif in the Integrin β3 Cytoplasmic Domain Is Required for Its Specific Interaction with β3-Endonexin

1997 • 72 citations

Molecular Basis of CIB Binding to the Integrin αIIb Cytoplasmic Domain

2002 • 62 citations

Calcium Integrin-binding Protein Activates Platelet Integrin αIIbβ3

2002 • 52 citations

Characterization of the Monomeric Form of the Transmembrane and Cytoplasmic Domains of the Integrin β3 Subunit by NMR Spectroscopy

2002 • 42 citations