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Defective Glomerulogenesis in the Absence of Laminin α5 Demonstrates a Developmental Role for the Kidney Glomerular Basement Membrane

Data up to Jan 2025

Published2000
Citations259
References54

Total Citations Per Year

Abstract

References (54)

Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities.

1994 • 1,123 citations

Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice.

1994 • 984 citations

Structure and biological activity of basement membrane proteins

1989 • 967 citations

Organogenesis of the kidney

1987 • 904 citations

Identification of Mutations in the COL4A5 Collagen Gene in Alport Syndrome

1990 • 847 citations

Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesis

1996 • 708 citations

Supramolecular assembly of basement membranes

1996 • 693 citations

The Laminin α Chains: Expression, Developmental Transitions, and Chromosomal Locations of α1-5, Identification of Heterotrimeric Laminins 8–11, and Cloning of a Novel α3 Isoform

1997 • 661 citations

Macromolecular organization of basement membranes

1996 • 661 citations

Basement Membrane Proteins: Structure, Assembly, and Cellular Interactions

1992 • 584 citations

cloche, an early acting zebrafish gene, is required by both the endothelial and hematopoietic lineages

1995 • 545 citations

Absence of Basement Membranes after Targeting the LAMC1 Gene Results in Embryonic Lethality Due to Failure of Endoderm Differentiation

1999 • 525 citations

Identification of mutations in the α3(IV) and α4(IV) collagen genes in autosomal recessive Alport syndrome

1994 • 495 citations

Role of laminin a chain in the development of epithelial cell polarity

1988 • 488 citations

Roles for Laminin in Embryogenesis: Exencephaly, Syndactyly, and Placentopathy in Mice Lacking the Laminin α5 Chain

1998 • 484 citations

Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase

1998 • 453 citations

Distribution and Function of Laminins in the Neuromuscular System of Developing, Adult, and Mutant Mice

1997 • 433 citations

The renal glomerulus of mice lacking s–laminin/laminin β2: nephrosis despite molecular compensation by laminin β1

1995 • 416 citations

Collagen COL4A3 knockout: a mouse model for autosomal Alport syndrome.

1996 • 374 citations

Integrin α8β1 Is Critically Important for Epithelial–Mesenchymal Interactions during Kidney Morphogenesis

1997 • 359 citations

Renal basement membrane components

1999 • 347 citations

Proteoglycans are required for maintenance of Wnt-11 expression in the ureter tips

1996 • 312 citations

Molecular and functional defects in kidneys of mice lacking collagen alpha 3(IV): implications for Alport syndrome.

1996 • 310 citations

Laminin Polymerization Induces a Receptor–Cytoskeleton Network

1999 • 307 citations

The role of laminins in basement membrane function

1998 • 303 citations

The alpha 1-alpha 6 subunits of integrins are characteristically expressed in distinct segments of developing and adult human nephron.

1990 • 261 citations

Characterization and Expression of the Laminin γ3 Chain: A Novel, Non-Basement Membrane–associated, Laminin Chain

1999 • 248 citations

Self-assembly of Laminin Isoforms

1997 • 235 citations

Mutations in the type IV collagen α3 (COL4A3) gene in autosomal recessive Alport syndrome

1994 • 212 citations

Isolation and Characterization of Laminin-10/11 Secreted by Human Lung Carcinoma Cells

1998 • 204 citations

Domains of laminin

1996 • 158 citations

Differential expression of five laminin α (1-5) chains in developing and adult mouse kidney

1997 • 152 citations

Dual origin of glomerular basement membrane

1984 • 144 citations

Origin of the glomerular basement membrane visualized after in vivo labeling of laminin in newborn rat kidneys.

1985 • 143 citations

Inductive Tissue Interactions, Cell Signaling, and the Control of Kidney Organogenesis

1997 • 137 citations

Insulin-like growth factors I and II are produced in the metanephros and are required for growth and development in vitro.

1991 • 129 citations

Developmental biology of glomerular basement membrane components

1998 • 125 citations

Sulphated proteoglycan is required for collecting duct growth and branching but not nephron formation during kidney development

1995 • 124 citations

Monoclonal antibodies against laminin A chain fragment E3 and their effects on binding to cells and proteoglycan and on kidney development

1992 • 122 citations

Canine X chromosome-linked hereditary nephritis: a genetic model for human X-linked hereditary nephritis resulting from a single base mutation in the gene encoding the alpha 5 chain of collagen type IV.

1994 • 116 citations

Podocyte differentiation in the absence of endothelial cells as revealed in the zebrafish avascular mutant,cloche

1999 • 106 citations

Distribution of the α1 and α2 chains of collagen IV and of collagens V and VI in Alport syndrome

1992 • 101 citations

Glomerular differentiation in metanephric culture.

1981 • 98 citations

Selective immunoreactivities of kidney basement membranes to monoclonal antibodies against laminin: localization of the end of the long arm and the short arms to discrete microdomains.

1989 • 97 citations

Development of tubular and glomerular cells of the kidney

1992 • 94 citations

8 The Development of the Kidney

1998 • 93 citations

The tip-top branching ureter

1997 • 88 citations

Distribution of ten laminin chains in dystrophic and regenerating muscles

1999 • 80 citations

Towards a genetic basis for kidney development

1994 • 77 citations

Molecular Cloning and Tissue-specific Expression of a Novel Murine Laminin γ3 Chain

1999 • 64 citations

Metanephric transforming growth factor-beta 1 regulates nephrogenesis in vitro

1993 • 61 citations

Expression of Laminins 1 and 10 in Carcinoma Cells and Comparison of Their Roles in Cell Adhesion

1999 • 59 citations

The regulation of kidney development: new insights from an old model

1994 • 32 citations

Deleted Work

1955 • 0 citations

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Defective Glomerulogenesis in the Absence of Laminin α5 Demonstrates a Developmental Role… (2000) – Developmental Biology | Metascience Observatory Explorer