Genomic Organization of the Mouse and Human Genes for Vascular Endothelial Growth Factor B (VEGF-B) and Characterization of a Second Splice Isoform

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Angiogenesis in cancer, vascular, rheumatoid and other disease

1995 • 7,717 citations

Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen

1989 • 4,988 citations

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

1995 • 3,977 citations

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

1995 • 2,650 citations

The fms -Like Tyrosine Kinase, a Receptor for Vascular Endothelial Growth Factor

1992 • 2,042 citations

The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing

1991 • 1,991 citations

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

1993 • 1,961 citations

A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases.

1996 • 1,670 citations

Dimerization of cell surface receptors in signal transduction

1995 • 1,631 citations

Molecular and Biological Properties of the Vascular Endothelial Growth Factor Family of Proteins

1992 • 1,612 citations

Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor

1992 • 1,528 citations

The Vascular Endothelial Growth Factor Family: Identification of a Fourth Molecular Species and Characterization of Alternative Splicing of RNA

1991 • 1,375 citations

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

1986 • 1,244 citations

SPLICING OF MESSENGER RNA PRECURSORS

1986 • 1,233 citations

Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR.

1994 • 1,104 citations

Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation

1992 • 1,103 citations

Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor.

1991 • 999 citations

Vascular endothelial growth factor B, a novel growth factor for endothelial cells.

1996 • 788 citations

A versatilein vivoandin vitroeukaryotic expression vector for protein engineering

1988 • 686 citations

Endothelial receptor tyrosine kinases involved in angiogenesis.

1995 • 537 citations

Platelet-derived growth factor: mechanism of action and possible in vivo function.

1990 • 491 citations

cDNA cloning and expression of the human A-type platelet-derived growth factor (PDGF) receptor establishes structural similarity to the B-type PDGF receptor.

1989 • 413 citations

Vascular endothelial growth factor-related protein: a ligand and specific activator of the tyrosine kinase receptor Flt4.

1996 • 406 citations

Characterization of Novel Vascular Endothelial Growth Factor (VEGF) Receptors on Tumor Cells That Bind VEGF165 via Its Exon 7-encoded Domain

1996 • 345 citations

cDNA cloning and expression of a human platelet-derived growth factor (PDGF) receptor specific for B-chain-containing PDGF molecules.

1988 • 338 citations

The Mouse Gene for Vascular Endothelial Growth Factor

1996 • 335 citations

Two alternative mRNAs coding for the angiogenic factor, placenta growth factor (PlGF), are transcribed from a single gene of chromosome 14.

1993 • 317 citations

Cloning and expression of a cDNA coding for the human platelet-derived growth factor receptor: evidence for more than one receptor class.

1988 • 314 citations

A Heparin-Binding Form of Placenta Growth Factor (PlGF-2) is Expressed in Human Umbilical Vein Endothelial Cells and in Placenta

1993 • 245 citations

The identification of O-glycosylated precursors of insulin-like growth factor II.

1992 • 44 citations

Post-translational Processing of Membrane-associated neu Differentiation Factor Proisoforms Expressed in Mammalian Cells

1995 • 43 citations