Novel nonsecosteroidal vitamin D mimics exert VDR-modulating activities with less calcium mobilization than 1,25-dihydroxyvitamin D3

The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed

1998 • 1,391 citations

Structure-Function Relationships in the Vitamin D Endocrine System*

1995 • 1,182 citations

Differentiation of mouse myeloid leukemia cells induced by 1 alpha,25-dihydroxyvitamin D3.

1981 • 1,025 citations

Cloning and expression of full-length cDNA encoding human vitamin D receptor.

1988 • 961 citations

1,25-Dihydroxyvitamin D3 reversibly blocks the progression of relapsing encephalomyelitis, a model of multiple sclerosis.

1996 • 729 citations

Normal functional characteristics of cultured human promyelocytic leukemia cells (HL-60) after induction of differentiation by dimethylsulfoxide.

1979 • 602 citations

Basic and Clinical Concepts Related to Vitamin D Metabolism and Action

1977 • 578 citations

1,25-DIHYDROXYVITAMIN D₃AND MALIGNANT MELANOMA: THE PRESENCE OF RECEPTORS AND INHIBITION OF CELL GROWTH IN CULTURE

1981 • 560 citations

1,25-Dihydroxyvitamin D ₃ : a Novel Immunoregulatory Hormone

1984 • 536 citations

The vitamin D story: a collaborative effort of basic science and clinical medicine ¹

1988 • 531 citations

Vitamin D and prostate cancer: 1,25 dihydroxyvitamin D3 receptors and actions in human prostate cancer cell lines.

1993 • 475 citations

1,25-Dihydroxyvitamin D3-induced differentiation in a human promyelocytic leukemia cell line (HL-60): receptor-mediated maturation to macrophage-like cells.

1984 • 461 citations

Induction of monocytic differentiation and bone resorption by 1,25-dihydroxyvitamin D3.

1983 • 424 citations

Suppression of in vivo growth of human cancer solid tumor xenografts by 1,25-dihydroxyvitamin D3.

1987 • 312 citations

1 alpha,25-Dihydroxyvitamin D3 and 1 alpha-hydroxyvitamin D3 prolong survival time of mice inoculated with myeloid leukemia cells.

1983 • 257 citations

Basic and Clinical Concepts Related to Vitamin D Metabolism and Action

1977 • 254 citations

1,25-Dihydroxyvitamin D ₃ Attenuates of Expression of Experimental Murine Lupus of MRL/1 Mice

1992 • 243 citations

Effects of synthetic vitamin d analogues on breast cancer cell proliferation in vivo and in vitro

1992 • 237 citations

EB1089: A new vitamin D analogue that inhibits the growth of breast cancer cells in vivo and in vitro

1992 • 224 citations

Improvement of psoriasis by a topical vitamin D3 analogue (MC 903) in a double-blind study

1988 • 209 citations

1,25-Dihydroxyvitamin D3 and 9-cis-Retinoic Acid Act Synergistically to Inhibit the Growth of LNCaP Prostate Cells and Cause Accumulation of Cells in G1*

1997 • 205 citations

A novel approach for the evaluation and treatment of psoriasis

1988 • 202 citations

20-epi-vitamin D3 analogues: a novel class of potent inhibitors of proliferation and inducers of differentiation of human breast cancer cell lines.

1995 • 188 citations

Transactivation properties of retinoic acid and retinoid X receptors in mammalian cells and yeast. Correlation with hormone binding and effects of metabolism.

1993 • 185 citations

Interactions of 1,25-dihydroxyvitamin D3 and the immune system

1985 • 181 citations

Prevention of type I diabetes in NOD mice by nonhypercalcemic doses of a new structural analog of 1,25-dihydroxyvitamin D3, KH1060.

1995 • 177 citations

Influence of 1,25-dihydroxyvitamin D3 on cultured osteogenic sarcoma cells: correlation with the 1,25-dihydroxyvitamin D3 receptor.

1984 • 144 citations

On the Mechanisms for the Selective Action of Vitamin D Analogs*

1991 • 139 citations

Functional antagonism between vitamin D3 and retinoic acid in the regulation of CD14 and CD23 expression during monocytic differentiation of U-937 cells.

1993 • 127 citations

Comparative study of the affinity of the serum vitamin d-binding protein

1980 • 121 citations

Reconstitution of the vitamin D-responsive osteocalcin transcription unit in Saccharomyces cerevisiae.

1989 • 101 citations

Perspectives: The genomic mechanism of action of 1,25-dihydroxyvitamin D3

1991 • 100 citations

Growth-inhibitory effects of vitamin D analogues and retinoids on human pancreatic cancer cells

1996 • 93 citations

A protective role of 1,25-dihydroxyvitamin D₃ in chemically induced rat colon carcinogenesis

1992 • 92 citations

Retinoid X Receptor (RXR) Ligands Activate the Human 25-Hydroxyvitamin D3-24-hydroxylase Promoter via RXR Heterodimer Binding to Two Vitamin D-responsive Elements and Elicit Additive Effects with 1,25-Dihydroxyvitamin D3

1997 • 89 citations

1 alpha, 25-dihydroxyvitamin D3 and all-trans-retinoic acid inhibit the growth of a lung cancer cell line.

1996 • 53 citations

Retinoid X Receptor Acts as a Hormone Receptor in Vivo to Induce a Key Metabolic Enzyme for 1,25-Dihydroxyvitamin D3

1995 • 50 citations

Effects of 1,25‐dihydroxyvitamin D₃ and its 20‐epi analogues (MC 1288, MC 1301, KH 1060), on clonal keratinocyte growth: evidence for differentiation of keratinocyte stem cells and analysis of the modulatory effects of cytokines

1997 • 26 citations

Intracellular free calcium and growth changes in single human keratinocytes in response to vitamin D and five 20-epi-analogues

1994 • 26 citations

Action of 1,25-(OH)2D3 in nude mice bearing transplantable human myelogenous leukemic cell lines.

1985 • 14 citations