Medroxyprogesterone Acetate Decreases Secretion of Interleukin-6 and Parathyroid Hormone-Related Protein in a New Anaplastic Thyroid Cancer Cell Line, KTC-2

A National Cancer Data Base report on 53,856 cases of thyroid carcinoma treated in the U.S., 1985-1995

1998 • 1,830 citations

Activation of the Src/p21ras/Erk pathway by progesterone receptor via cross-talk with estrogen receptor

1998 • 618 citations

Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor

2001 • 397 citations

The Opposing Transcriptional Activities of the Two Isoforms of the Human Progesterone Receptor Are Due to Differential Cofactor Binding

2000 • 375 citations

Androgen Receptor: An Overview

1995 • 322 citations

Treatment of Anaplastic Thyroid Carcinoma with Paclitaxel: Phase 2 Trial Using Ninety-Six-hour Infusion

2000 • 298 citations

On the mechanism for efficient repression of the interleukin-6 promoter by glucocorticoids: enhancer, TATA box, and RNA start site (Inr motif) occlusion.

1990 • 279 citations

8-Bromo-Cyclic AMP Induces Phosphorylation of Two Sites in SRC-1 That Facilitate Ligand-Independent Activation of the Chicken Progesterone Receptor and Are Critical for Functional Cooperation between SRC-1 and CREB Binding Protein

2000 • 248 citations

Expression levels of estrogen receptor-alpha, estrogen receptor-beta, coactivators, and corepressors in breast cancer.

2000 • 227 citations

SMAD3 represses androgen receptor-mediated transcription.

2001 • 194 citations

A Nuclear Receptor Corepressor Modulates Transcriptional Activity of Antagonist-Occupied Steroid Hormone Receptor

1998 • 168 citations

Combined doxorubicin, hyperfractionated radiotherapy, and surgery in anaplastic thyroid carcinoma. Report on two protocols

1994 • 158 citations

Fibroblast growth factor 4 transfection of MCF-7 cells produces cell lines that are tumorigenic and metastatic in ovariectomized or tamoxifen-treated athymic nude mice.

1993 • 125 citations

EVIDENCE THAT GLUCOCORTICOSTEROIDS BLOCK EXPRESSION OF THE HUMAN INTERLEUKIN-6 GENE BY ACCESSORY CELLS

1990 • 124 citations

Anaplastic Thyroid Carcinoma: Association With Differentiated Thyroid Cancer

1988 • 124 citations

All-Trans-Retinoic Acid Modulates Expression Levels of Thyroglobulin and Cytokines in a New Human Poorly Differentiated Papillary Thyroid Carcinoma Cell Line, KTC-1¹

2000 • 109 citations

Androgen receptor agonist activity of the synthetic progestin, medroxyprogesterone acetate, in human breast cancer cells

1999 • 108 citations

Estrogen, androgen, glucocorticoid, and progesterone receptors in progestin-induced regression of human breast cancer.

1980 • 103 citations

Repression of Glucocorticoid Receptor Transactivation and DNA Binding of a Glucocorticoid Response Element within the Serum/Glucocorticoid-Inducible Protein Kinase (sgk) Gene Promoter by the p53 Tumor Suppressor Protein

1997 • 97 citations

Fatal thyroid carcinoma:Anaplastic transformation of adenocarcinoma

1977 • 91 citations

Medroxyprogesterone acetate therapy in advanced breast cancer: the predictive value of androgen receptor expression.

1995 • 87 citations

Androgen and glucocorticoid receptor-mediated inhibition of cell proliferation by medroxyprogesterone acetate in ZR-75-1 human breast cancer cells

1989 • 85 citations

The Anti-Androgen Hydroxyflutamide and Androgens Inhibit Interleukin-6 Production by an Androgen-Responsive Human Osteoblastic Cell Line

1999 • 80 citations

All-Trans-Retinoic Acid Modulates Expression Levels of Thyroglobulin and Cytokines in a New Human Poorly Differentiated Papillary Thyroid Carcinoma Cell Line, KTC-1

2000 • 74 citations

Multiple actions of synthetic ‘progestins’ on the growth of ZR-75-1 human breast cancer cells: Anin vitro model for the simultaneous assay of androgen, progestin, estrogen, and glucocorticoid agonistic and antagonistic activities of steroids

1991 • 73 citations

Phase II evaluation of high dose accelerated radiotherapy for anaplastic thyroid carcinoma

1999 • 71 citations

Glucocorticoid Receptor Interaction with 14-3-3 and Raf-1, a Proposed Mechanism for Cross-talk of Two Signal Transduction Pathways

2000 • 60 citations

Regulation of parathyroid hormone-related peptide production in normal human mammary epithelial cells in vitro

1994 • 59 citations

Regulation of parathyroid hormone-related peptide production in vitro by the rat hypercalcemic Leydig cell tumor H-500.

1993 • 59 citations

Medroxyprogesterone acetate inhibits the proliferation of estrogen- and progesterone-receptor negative MFM-223 human mammary cancer cells via the androgen receptor

1993 • 58 citations

A Nuclear Receptor Corepressor Modulates Transcriptional Activity of Antagonist-Occupied Steroid Hormone Receptor

1998 • 54 citations

Establishment of a human undifferentiated thyroid cancer cell line producing several growth factors and cytokines

1990 • 54 citations

Differential ligand-dependent protein–protein interactions between nuclear receptors and a neuronal-specific cofactor

2000 • 48 citations

Neutrophilia Associated with Anaplastic Carcinoma of the Thyroid: Production of Macrophage Colony-Stimulating Factor (M-CSF) and lnterleukin-6

2000 • 45 citations

A new human breast cancer cell line, KPL-3C, secretes parathyroid hormone-related protein and produces tumours associated with microcalcifications in nude mice

1996 • 43 citations

Thyroid Anaplastic Carcinoma Producing Granulocyte-Colony-Stimulating Factor and Parathyroid Hormone-Related Protein.

1995 • 42 citations

Cytokine Production by a New Undifferentiated Human Thyroid Carcinoma Cell Line, FB-11

1997 • 42 citations

Dexamethasone regulation of parathyroid hormone-related protein (PTHrP) expression in a squamous cancer cell line

1994 • 42 citations

Molecular basis of glucocorticoid-resistant syndromes

1996 • 38 citations

Medroxyprogesterone acetate inhibits interleukin 6 secretion from KPL-4 human breast cancer cells both in vitro and in vivo: a possible mechanism of the anticachectic effect

1999 • 36 citations

Production of Multiple Growth Factors by a Newly Established Human Thyroid Carcinoma Cell Line

1992 • 33 citations

Medroxyprogesterone acetate: Receptor binding and correlated effects on steroidogenesis in rat granulosa cells

1987 • 33 citations

Glucocorticoid‐mediated repression of inflammatory cytokine production in fibroblast‐like rheumatoid synoviocytes is independent of nuclear factor‐κB activation induced by tumour necrosis factor α

2001 • 30 citations

Regulation of Interleukin-1 -Induced Interleukin-6 Gene Expression in Human Fibroblast-Like Synoviocytes by Glucocorticoids

1998 • 28 citations

Repression of Glucocorticoid Receptor Transactivation and DNA Binding of a Glucocorticoid Response Element within the Serum/Glucocorticoid-Inducible Protein Kinase (sgk) Gene Promoter by the p53 Tumor Suppressor Protein

1997 • 22 citations

Cytokine Production by a New Undifferentiated Human Thyroid Carcinoma Cell Line, FB-1

1997 • 22 citations

The secretion of cytokines and granulocyte colony stimulating factor by anaplastic and poorly differentiated thyroid carcinoma cell lines.

1999 • 20 citations

Regulation of parathyroid hormone-related peptide production in vitro by the rat hypercalcemic Leydig cell tumor H-500

1993 • 19 citations

Production of cytokines by thyroid carcinoma cell lines

1994 • 15 citations