How were introns inserted into nuclear genes?

On the origin of RNA splicing and introns

1985 • 483 citations

A self-splicing RNA excises an intron lariat

1986 • 449 citations

Genes in pieces: were they ever together?

1978 • 440 citations

Excised group II introns in yeast mitochondria are lariats and can be formed by self-splicing in vitro

1986 • 346 citations

On the antiquity of introns

1986 • 324 citations

Pseudogenes in yeast?

1987 • 316 citations

An RNA Processing Activity That Debranches RNA Lariats

1985 • 300 citations

Mitochondrial class II introns encode proteins related to the reverse transcriptases of retroviruses

1985 • 294 citations

Splice Junctions: Association with Variation in Protein Structure

1983 • 261 citations

Split-gene evolution: Exon shuffling and intron insertion in serine protease genes

1985 • 217 citations

The mitochondrial plasmid of Podospora anserina: A mobile intron of a mitochondrial gene

1984 • 198 citations

Infectious introns

1989 • 153 citations

Functional expression of a sequence-specific endonuclease encoded by the retrotransposon R2Bm

1988 • 150 citations

Unusual intron in the immunoglobulin domain of the newly isolated murine CD4 (L3T4) gene

1987 • 127 citations

Structure of tbe gene forXenopustranscription factor TMIIIA

1986 • 108 citations

Tissue-specific expression of rat myosin light-chain 2 gene in transgenic mice

1985 • 105 citations

The Maize Transposable Element Ds Is Spliced from RNA

1987 • 102 citations

Structure and sequence of the Drosophila melanogaster calmodulin gene

1987 • 100 citations

Structure of chick chromosomal genes for calbindin and calretinin

1988 • 72 citations

Structural organization and chromosomal assignment of the parvalbumin gene.

1987 • 68 citations

The chicken carbonic anhydrase II gene: evidence for a recent shift in intron position

1987 • 45 citations

Long-range Intron-Exon and Intron-Intron Pairings Involved in Self-splicing of Class II Catalytic Introns

1987 • 45 citations

Self-splicing of a group II intron in yeast mitochondria: dependence on 5′ exon sequences.

1987 • 27 citations

Group I introns: do they only go home?

1989 • 23 citations

Introns between protein domains: selective insertion or frameshifting?

1986 • 19 citations

Introns continue to amaze

1985 • 12 citations

Does nuclear integration of mitochondrial sequences occur during senescence in Podospora?

1986 • 9 citations